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View Structure Prediction Details

Protein: PABP_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 653 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PABP_SCHPO.

Description E-value Query
Range
Subject
Range
gi|73976801 - gi|73976801|ref|XP_857781.1| PREDICTED: similar to Polyadenylate-binding protein 4 (Poly(A)-binding ...
500.0 [0..72] [651..3]
gi|55959640, gi|... - gi|55962218|emb|CAI12299.1| poly(A) binding protein, cytoplasmic 4 (inducible form) [Homo sapiens], ...
498.0 [0..72] [651..3]
gi|76689291 - gi|76689291|ref|XP_881690.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 2 ...
496.0 [0..72] [651..3]

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Predicted Domain #1
Region A:
Residues: [1-73]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSTDLKKQA DAAVESDVNT NNEAVESSTK EESSNTPSTE TQPEKKAEEP EAAAEPSEST  60
   61 STPTNASSVA TPS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.0
Match: 1hl6A
Description: CG8781 protein
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [74-254]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTAPTSASLY VGELDPSVTE AMLFELFNSI GPVASIRVCR DAVTRRSLGY AYVNFHNMED  60
   61 GEKALDELNY TLIKGRPCRI MWSQRDPSLR KMGTGNVFIK NLDPAIDNKA LHDTFSAFGK 120
  121 ILSCKVAVDE LGNAKGYGFV HFDSVESANA AIEHVNGMLL NDKKVYVGHH VSRRERQSKV 180
  181 E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.221849
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
structural molecule activity 4.28696884073791 bayes_pls_golite062009
snRNA binding 4.06596327298973 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
translation initiation factor activity 3.27900316559423 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
U1 snRNA binding 3.02511982045347 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
transcription regulator activity 2.18211199677674 bayes_pls_golite062009
DNA binding 1.98418556946403 bayes_pls_golite062009
U2 snRNA binding 1.34078165372485 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription factor activity 1.07843408116687 bayes_pls_golite062009
mRNA 3'-UTR binding 0.824614388276642 bayes_pls_golite062009
transporter activity 0.417047632648771 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009
translation regulator activity 0.38120065819101 bayes_pls_golite062009
transmembrane transporter activity 0.288804044686487 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.128616879457381 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00171911393626201 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [255-348]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALKANFTNVY IKNLDTEITE QEFSDLFGQF GEITSLSLVK DQNDKPRGFG FVNYANHECA  60
   61 QKAVDELNDK EYKGKKLYVG RAQKKHEREE ELRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.69897
Match: 1o0pA
Description: Splicing factor U2AF 65 KDa subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
structural molecule activity 4.28696884073791 bayes_pls_golite062009
snRNA binding 4.06596327298973 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
translation initiation factor activity 3.27900316559423 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
U1 snRNA binding 3.02511982045347 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
transcription regulator activity 2.18211199677674 bayes_pls_golite062009
DNA binding 1.98418556946403 bayes_pls_golite062009
U2 snRNA binding 1.34078165372485 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription factor activity 1.07843408116687 bayes_pls_golite062009
mRNA 3'-UTR binding 0.824614388276642 bayes_pls_golite062009
transporter activity 0.417047632648771 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009
translation regulator activity 0.38120065819101 bayes_pls_golite062009
transmembrane transporter activity 0.288804044686487 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.128616879457381 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00171911393626201 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [349-453]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RYEQMKLEKM NKYQGVNLFI KNLQDEVDDE RLKAEFSAFG TITSAKIMTD EQGKSKGFGF  60
   61 VCYTTPEEAN KAVTEMNQRM LAGKPLYVAL AQRKEVRRSQ LEAQI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.63
Match: 2f3jA
Description: No description for 2f3jA was found.

Predicted Domain #5
Region A:
Residues: [454-653]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QARNQFRLQQ QVAAAAGIPA VQYGATGPLI YGPGGYPIPA AVNGRGMPMV PGHNGPMPMY  60
   61 PGMPTQFPAG GPAPGYPGMN ARGPVPAQGR PMMMPGSVPS AGPAEAEAVP AVPGMPERFT 120
  121 AADLAAVPEE SRKQVLGELL YPKVFVREEK LSGKITGMLL EMPNSELLEL LEDDSALNER 180
  181 VNEAIGVLQE FVDQEPGFTE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.522879
Match: 1g9lA
Description: poly(A) binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 5.69788763665792 bayes_pls_golite062009
mRNA binding 5.31297072316889 bayes_pls_golite062009
single-stranded RNA binding 4.51056428709072 bayes_pls_golite062009
nucleic acid binding 3.78909647605682 bayes_pls_golite062009
eukaryotic initiation factor 4G binding 3.4111148675327 bayes_pls_golite062009
binding 2.76167454154417 bayes_pls_golite062009
poly(A) RNA binding 2.66269581586161 bayes_pls_golite062009
poly-purine tract binding 2.20136693536924 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.19350242454642 bayes_pls_golite062009
small conjugating protein ligase activity 1.14692713780316 bayes_pls_golite062009
protein binding 0.856075580719879 bayes_pls_golite062009
ligase activity 0.38737123012383 bayes_pls_golite062009
catalytic activity 0.287695754348243 bayes_pls_golite062009
acid-amino acid ligase activity 0.223805219849164 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle