| Protein: | Dscam-PF |
| Organism: | Drosophila melanogaster |
| Length: | 2031 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dscam-PF.
| Description | E-value | Query Range |
Subject Range |
|
|
1544.0 | [0..3] | [2031..3] |
|
Region A: Residues: [1-138] |
1 11 21 31 41 51
| | | | | |
1 MNMPNERLKW LMLFAAVALI ACGSQTLAAN PPDADQKGPV FLKEPTNRID FSNSTGAEIE 60
61 CKASGNPMPE IIWIRSDGTA VGDVPGLRQI SSDGKLVFPP FRAEDYRQEV HAQVYACLAR 120
121 NQFGSIISRD VHVRAVVA
|
| Detection Method: |  |
| Confidence: | 81.045757 |
| Match: | 2v5sA |
| Description: | No description for 2v5sA was found. |
|
Region A: Residues: [139-253] |
1 11 21 31 41 51
| | | | | |
1 QYYEADVNKE HVIRGNSAVI KCLIPSFVAD FVEVVSWHTD EEENYFPGAE YDGKYLVLPS 60
61 GELHIREVGP EDGYKSYQCR TKHRLTGETR LSATKGRLVI TEPIASVGPR LLSGN
|
| Detection Method: | |
| Confidence: | 20.522879 |
| Match: | 2e9wA |
| Description: | No description for 2e9wA was found. |
|
Region A: Residues: [254-909] |
1 11 21 31 41 51
| | | | | |
1 DIKVLQFSAS QASTLLCPAQ SYPVPVFRWY KFIEGTTRKQ AVVLNDRVKQ VSGTLIIKDA 60
61 VVEDSGKYLC VVNNSVGGES VETVLTVTAP LSAKIDPPTQ TVDFGRPAVF TCQYTGNPIK 120
121 TVSWMKDGKA IGHSEPVLRI ESVKKEDKGM YQCFVRNDQE SAEASAELKL GGRFDPPVIR 180
181 QAFQEETMEP GPSVFLKCVA GGNPTPEISW ELDGKKIANN DRYQVGQYVT VNGDVVSYLN 240
241 ITSVHANDGG LYKCIAKSKV GVAEHSAKLN VYGLPYIRQM EKKAIVAGET LIVTCPVAGY 300
301 PIDSIVWERD NRALPINRKQ KVFPNGTLII ENVERNSDQA TYTCVAKNQE GYSARGSLEV 360
361 QVMVAPKIAS FDFGEEPLNY GEPASVQCTI LGGDLPMNVT WLLNNATIDS FHDISFSRIG 420
421 KRINVLSIES VSAHHAGFYS CHAQNKAGIT AHSARLIVNV PPRWILEPTD KAFAQGSDAK 480
481 VECKADGFPK PQVTWKKAVG DTPGEYKDLK KSDNIRVEEG TLHVDNIQKT NEGYYLCEAI 540
541 NGIGSGLSAV IMISVQAPPE FTEKLRNQTA RRGEPAVLQC EAKGEKPIGI LWNMNNMRLD 600
601 PKNDNRYTIR EEILSTGVMS SLSIKRTERS DSALFTCVAT NAFGSDDASI NMIVQE
|
| Detection Method: | |
| Confidence: | 60.69897 |
| Match: | 1e07A |
| Description: | Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [910-1008] |
1 11 21 31 41 51
| | | | | |
1 VPEMPYALKV LDKSGRSVQL SWAQPYDGNS PLDRYIIEFK RSRASWSEID RVIVPGHTTE 60
61 AQVQKLSPAT TYNIRIVAEN AIGTSQSSEA VTIITAEEA
|
| Detection Method: | |
| Confidence: | 37.69897 |
| Match: | 2nziA |
| Description: | No description for 2nziA was found. |
|
Region A: Residues: [1009-1114] |
1 11 21 31 41 51
| | | | | |
1 PSGKPQNIKV EPVNQTTMRV TWKPPPRTEW NGEILGYYVG YKLSNTNSSY VFETINFITE 60
61 EGKEHNLELQ NLRVYTQYSV VIQAFNKIGA GPLSEEEKQF TAEGTP
|
| Detection Method: | |
| Confidence: | 11.0 |
| Match: | 2edxA |
| Description: | No description for 2edxA was found. |
|
Region A: Residues: [1115-1213] |
1 11 21 31 41 51
| | | | | |
1 SQPPSDTACT TLTSQTIRVG WVSPPLESAN GVIKTYKVVY APSDEWYDET KRHYKKTASS 60
61 DTVLHGLKKY TNYTMQVLAT TAGGDGVRSV PIHCQTEPD
|
| Detection Method: | |
| Confidence: | 12.0 |
| Match: | 1x5hA |
| Description: | The solution structure of the third fibronectin type III domain of human Neogenin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1214-1482] |
1 11 21 31 41 51
| | | | | |
1 VPEAPTDVKA LVMGNAAILV SWRPPAQPNG IITQYTVYSK AEGAETETKT QKVPHYQMSF 60
61 EATELEKNKP YEFWVTASTT IGEGQQSKSI VAMPSDQVPA KIASFDDTFT ATFKEDAKMP 120
121 CLAVGAPQPE ITWKIKGVEF SANDRMRVLP DGSLLIKSVN RQDAGDYSCH AENSIAKDSI 180
181 THKLIVLAPP QSPHVTLSAT TTDALTVKLK PHEGDTAPLH GYTLHYKPEF GEWETSEVSV 240
241 DSQKHNIEGL LCGSRYQVYA TGFNNIGAG
|
| Detection Method: | |
| Confidence: | 12.522879 |
| Match: | 1tdqA |
| Description: | Structural basis for the interactions between tenascins and the C-type lectin domains from lecticans: evidence for a cross-linking role for tenascins |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
| structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
| ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
| alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
| actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
| transmembrane receptor activity | 3.79244614134061 | bayes_pls_golite062009 |
| receptor activity | 3.73567137429359 | bayes_pls_golite062009 |
| cytokine binding | 3.58426984827737 | bayes_pls_golite062009 |
| molecular transducer activity | 3.5100441341515 | bayes_pls_golite062009 |
| signal transducer activity | 3.5100441341515 | bayes_pls_golite062009 |
| cytokine receptor activity | 3.25206686803048 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| binding | 3.12471204223368 | bayes_pls_golite062009 |
| growth factor binding | 2.4970104838834 | bayes_pls_golite062009 |
| receptor binding | 2.38673889309915 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| prolactin receptor activity | 1.9556649101819 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
| interleukin-2 binding | 1.67132604890013 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 1.56410665522466 | bayes_pls_golite062009 |
| interleukin-6 binding | 1.53073516901486 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 1.53073516901486 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
| mercury ion binding | 1.46191698606762 | bayes_pls_golite062009 |
| protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
| transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 1.27192437373177 | bayes_pls_golite062009 |
| peptide hormone binding | 1.2420090521345 | bayes_pls_golite062009 |
| actin binding | 1.21472460452555 | bayes_pls_golite062009 |
| DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
| heparin binding | 1.15000556789505 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
| kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
| extracellular matrix structural constituent | 1.1057194345531 | bayes_pls_golite062009 |
| cytokine activity | 1.09433218752101 | bayes_pls_golite062009 |
| structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| growth hormone receptor activity | 0.840187286074179 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
| collagen binding | 0.593745877718282 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
| polysaccharide binding | 0.54737137289904 | bayes_pls_golite062009 |
| cytokine receptor binding | 0.47107517390107 | bayes_pls_golite062009 |
| pattern binding | 0.44460010885883 | bayes_pls_golite062009 |
| growth factor activity | 0.432629984792427 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
| protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
| cell surface binding | 0.366415248711076 | bayes_pls_golite062009 |
| interleukin-7 binding | 0.301052531308189 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
| transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
| actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
| protease binding | 0.12595904253108 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| interleukin-2 receptor activity | 0.115337814289139 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
| interleukin-11 binding | 0.0423783987133706 | bayes_pls_golite062009 |
| interleukin-11 receptor activity | 0.0423783987133706 | bayes_pls_golite062009 |
|
Region A: Residues: [1483-1594] |
1 11 21 31 41 51
| | | | | |
1 EASDILNTRT KGQKPKLPEK PRFIEVSSNS VSLHFKAWKD GGCPMSHFVV ESKKRDQIEW 60
61 NQISNNVKPD NNYVVLDLEP ATWYNLRITA HNSAGFTVAE YDFATLTVTG GT
|
| Detection Method: | |
| Confidence: | 19.69897 |
| Match: | 1fnhA |
| Description: | Fibronectin, different Fn3 modules |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
| structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
| ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
| alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
| actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
| transmembrane receptor activity | 3.79244614134061 | bayes_pls_golite062009 |
| receptor activity | 3.73567137429359 | bayes_pls_golite062009 |
| cytokine binding | 3.58426984827737 | bayes_pls_golite062009 |
| molecular transducer activity | 3.5100441341515 | bayes_pls_golite062009 |
| signal transducer activity | 3.5100441341515 | bayes_pls_golite062009 |
| cytokine receptor activity | 3.25206686803048 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| binding | 3.12471204223368 | bayes_pls_golite062009 |
| growth factor binding | 2.4970104838834 | bayes_pls_golite062009 |
| receptor binding | 2.38673889309915 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| prolactin receptor activity | 1.9556649101819 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
| interleukin-2 binding | 1.67132604890013 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 1.56410665522466 | bayes_pls_golite062009 |
| interleukin-6 binding | 1.53073516901486 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 1.53073516901486 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
| mercury ion binding | 1.46191698606762 | bayes_pls_golite062009 |
| protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
| transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 1.27192437373177 | bayes_pls_golite062009 |
| peptide hormone binding | 1.2420090521345 | bayes_pls_golite062009 |
| actin binding | 1.21472460452555 | bayes_pls_golite062009 |
| DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
| heparin binding | 1.15000556789505 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
| kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
| extracellular matrix structural constituent | 1.1057194345531 | bayes_pls_golite062009 |
| cytokine activity | 1.09433218752101 | bayes_pls_golite062009 |
| structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| growth hormone receptor activity | 0.840187286074179 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
| collagen binding | 0.593745877718282 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
| polysaccharide binding | 0.54737137289904 | bayes_pls_golite062009 |
| cytokine receptor binding | 0.47107517390107 | bayes_pls_golite062009 |
| pattern binding | 0.44460010885883 | bayes_pls_golite062009 |
| growth factor activity | 0.432629984792427 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
| protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
| cell surface binding | 0.366415248711076 | bayes_pls_golite062009 |
| interleukin-7 binding | 0.301052531308189 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
| transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
| actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
| protease binding | 0.12595904253108 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| interleukin-2 receptor activity | 0.115337814289139 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
| interleukin-11 binding | 0.0423783987133706 | bayes_pls_golite062009 |
| interleukin-11 receptor activity | 0.0423783987133706 | bayes_pls_golite062009 |
|
Region A: Residues: [1595-1836] |
1 11 21 31 41 51
| | | | | |
1 IAPLDDGSGH GNVHTRIRLP AWMPEWLDLN FMVPLIATVV VVAVGICVVC VALSRRRADD 60
61 MRGGQKDVYY DVVYNQTMGP GATLDKRRPD LRDELGYIAP PNRKLPPVPG SNYNTCDRIK 120
121 RGRGGLRSNH STWDPRRNPN LYEELKAPPV PMHGNHYGHA HGNAECHYRH PGMEDEICPY 180
181 ATFHLLGFRE EMDPTKAMNF QTFPHQNGHA GPVPGHAGTM LPPGHPGHVH SRSGSQSMPR 240
241 AN
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1837-2031] |
1 11 21 31 41 51
| | | | | |
1 RYQRKNSQGG QSSIYTPAPE YDDPANCAEE DQYRRYTRVN SQGGSLYSGP GPEYDDPANC 60
61 APEEDQYGSQ YGGPYGQPYD HYGSRGSMGR RSIGSARNPG NGSPEPPPPP PRNHDMSNSS 120
121 FNDSKESNEI SEAECDRDHG PRGNYGAVKR SPQPKDQRTT EEMRKLIERN ETGPKQLQLQ 180
181 QANGAGFTAY DTMAV
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
