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View Structure Prediction Details

Protein: B2CL2_MOUSE
Organism: Mus musculus
Length: 193 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for B2CL2_MOUSE.

Description E-value Query
Range
Subject
Range
gi|32185285 - gi|32185285|gb|AAO64470.1| BCL-WEL [Rattus norvegicus]
233.0 [0..1] [193..27]
gi|115607132 - gi|115607132|gb|ABJ16412.1| BCL2L2 [Felis catus]
232.0 [0..1] [193..17]
gi|61355774, gi|... - gi|61363348|gb|AAX42375.1| BCL2-like 2 [synthetic construct], gi|61355774|gb|AAX41175.1| BCL2-like 2...
B2CL2_BOVIN - Bcl-2-like protein 2 OS=Bos taurus GN=BCL2L2 PE=1 SV=1
BCL2L2 - BCL2-like 2
gi|149756246 - gi|149756246|ref|XP_001493744.1| PREDICTED: similar to Apoptosis regulator Bcl-W (Bcl-2-like 2 prote...
CCDS9591.1_1 - null
ENSPTRT00000011308 - null
B2CL2_CANLF - Bcl-2-like protein 2 OS=Canis lupus familiaris GN=BCL2L2 PE=2 SV=1
231.0 [0..1] [193..1]
gi|60654237 - gi|60654237|gb|AAX29811.1| BCL2-like 2 [synthetic construct]
231.0 [0..1] [193..1]
gi|116292133 - gi|116292133|dbj|BAF35574.1| BCL2-like 2 [Bos taurus]
230.0 [0..1] [193..1]
gi|50510435 - gi|50510435|dbj|BAD32203.1| mKIAA0271 protein [Mus musculus]
227.0 [0..1] [190..2]

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Predicted Domain #1
Region A:
Residues: [1-193]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATPASTPDT RALVADFVGY KLRQKGYVCG AGPGEGPAAD PLHQAMRAAG DEFETRFRRT  60
   61 FSDLAAQLHV TPGSAQQRFT QVSDELFQGG PNWGRLVAFF VFGAALCAES VNKEMEPLVG 120
  121 QVQDWMVAYL ETRLADWIHS SGGWAEFTAL YGDGALEEAR RLREGNWASV RTVLTGAVAL 180
  181 GALVTVGAFF ASK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.39794
Match: 1o0lA
Description: Apoptosis regulator Bcl-w
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
BH3 domain binding 9.28246182170242 bayes_pls_golite062009
BH domain binding 8.83760713740846 bayes_pls_golite062009
death domain binding 4.8394058973128 bayes_pls_golite062009
protein binding 3.0436105050182 bayes_pls_golite062009
binding 3.02494522439205 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.56711635370268 bayes_pls_golite062009
protein heterodimerization activity 2.30750502110235 bayes_pls_golite062009
caspase inhibitor activity 2.08013825948248 bayes_pls_golite062009
protein dimerization activity 2.02084894683525 bayes_pls_golite062009
transcription regulator activity 2.00561321127496 bayes_pls_golite062009
protein channel activity 1.83757523421791 bayes_pls_golite062009
caspase regulator activity 1.49377208228548 bayes_pls_golite062009
transcription activator activity 1.39638262328672 bayes_pls_golite062009
transporter activity 1.34634197931778 bayes_pls_golite062009
protein transporter activity 1.1517476263294 bayes_pls_golite062009
cysteine-type endopeptidase inhibitor activity 1.14864482798901 bayes_pls_golite062009
transmembrane transporter activity 1.13326310611172 bayes_pls_golite062009
substrate-specific transporter activity 0.883581589968833 bayes_pls_golite062009
passive transmembrane transporter activity 0.820061270030648 bayes_pls_golite062009
channel activity 0.820061270030648 bayes_pls_golite062009
identical protein binding 0.674037751773281 bayes_pls_golite062009
protein domain specific binding 0.65180328571488 bayes_pls_golite062009
protein transmembrane transporter activity 0.47363055480226 bayes_pls_golite062009
transcription factor binding 0.378563401155359 bayes_pls_golite062009
protease binding 0.0920295451817308 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle