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View Structure Prediction Details

Protein: CALCB
Organism: Homo sapiens
Length: 127 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CALCB.

Description E-value Query
Range
Subject
Range
gi|109107198 - gi|109107198|ref|XP_001092199.1| PREDICTED: calcitonin-related polypeptide, beta [Macaca mulatta]
1.0E-57 [1..127] [1..127]
CALCA - calcitonin-related polypeptide alpha
3.0E-56 [1..127] [1..128]
gi|114636335 - gi|114636335|ref|XP_529390.2| PREDICTED: similar to Calcitonin gene-related peptide 2 precursor (Cal...
5.0E-56 [1..127] [12..138]
CALCA_RAT - Calcitonin gene-related peptide 1 OS=Rattus norvegicus GN=Calca PE=2 SV=1
3.0E-53 [1..127] [1..128]
CALCA_CHICK - Calcitonin gene-related peptide OS=Gallus gallus GN=CALCA PE=2 SV=2
4.0E-52 [1..126] [1..124]
CALCA_HORSE - Calcitonin gene-related peptide 1 OS=Equus caballus GN=CALCA PE=2 SV=1
1.0E-51 [1..127] [1..127]
CRSP3_PIG - Calcitonin receptor-stimulating peptide 3 OS=Sus scrofa GN=CRSP3 PE=2 SV=1
2.0E-51 [1..127] [1..125]
gi|116062123, gi... - gi|157278525|ref|NP_001098364.1| calcitonin gene-related peptide 2 [Oryzias latipes], gi|116062123|d...
2.0E-51 [1..126] [1..125]
CALCB_MOUSE - Calcitonin gene-related peptide 2 OS=Mus musculus GN=Calcb PE=2 SV=1
3.0E-51 [1..127] [1..130]

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Predicted Domain #1
Region A:
Residues: [1-127]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFRKFSPFL ALSILVLYQA GSLQAAPFRS ALESSPDPAT LSKEDARLLL AALVQDYVQM  60
   61 KASELKQEQE TQGSSSAAQK RACNTATCVT HRLAGLLSRS GGMVKSNFVP TNVGSKAFGR 120
  121 RRRDLQA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.0
Match: 2cujA
Description: Solution structure of SWIRM domain of mouse transcriptional adaptor 2-like
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.86538715425734 bayes_pls_golite062009
DNA binding 4.40186699787632 bayes_pls_golite062009
nucleic acid binding 3.98153794570167 bayes_pls_golite062009
transcription factor activity 3.78935192723648 bayes_pls_golite062009
transcription repressor activity 3.3280771187468 bayes_pls_golite062009
binding 2.92574888336072 bayes_pls_golite062009
sequence-specific DNA binding 2.15328641013602 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.00875399167309 bayes_pls_golite062009
protein binding 1.84594855626241 bayes_pls_golite062009
transcription activator activity 1.5973137667873 bayes_pls_golite062009
transcription corepressor activity 1.30723796612579 bayes_pls_golite062009
transcription factor binding 1.24678737091956 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.865913662624162 bayes_pls_golite062009
receptor binding 0.84352520858745 bayes_pls_golite062009
transcription cofactor activity 0.691780246385357 bayes_pls_golite062009
chromatin binding 0.65622150362507 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.559548167984685 bayes_pls_golite062009
signal transducer activity 0.335245714099848 bayes_pls_golite062009
molecular transducer activity 0.335245714099848 bayes_pls_golite062009
G-protein coupled receptor activity 0.162991552651154 bayes_pls_golite062009

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