YRC Public Data Repository - Protein Structure Prediction

Protein:	GINS4
Organism:	Homo sapiens
Length:	223 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GINS4.

Description	E-value	Query Range	Subject Range
gi\|76655942 - gi\|76655942\|ref\|XP_874005.1\| PREDICTED: similar to SLD5 [Bos taurus]	1.0E-84	[1..223]	[267..489]
gi\|114619902 - gi\|114619902\|ref\|XP_001138293.1\| PREDICTED: SLD5 [Pan troglodytes]	3.0E-78	[1..223]	[1..223]
SLD5_MOUSE - DNA replication complex GINS protein SLD5 OS=Mus musculus GN=Gins4 PE=1 SV=1	5.0E-78	[1..223]	[1..223]
gi\|109086239 - gi\|109086239\|ref\|XP_001094432.1\| PREDICTED: similar to SLD5 [Macaca mulatta]	7.0E-78	[1..223]	[1..223]
gi\|73979207 - gi\|73979207\|ref\|XP_539958.2\| PREDICTED: similar to SLD5 [Canis familiaris]	2.0E-77	[1..223]	[69..292]
SLD5_RAT - DNA replication complex GINS protein SLD5 OS=Rattus norvegicus GN=Gins4 PE=1 SV=1	1.0E-76	[1..223]	[1..223]
gi\|46249482, gi\|... - gi\|46249482\|gb\|AAH68670.1\| MGC81062 protein [Xenopus laevis], gi\|29365477\|dbj\|BAC66457.1\| Sld5 [Xeno...	2.0E-70	[1..223]	[1..221]
gi\|58332332, gi\|... - gi\|58332332\|ref\|NP_001011045.1\| hypothetical LOC496455 [Xenopus (Silurana) tropicalis], gi\|54038183\|...	2.0E-69	[1..223]	[1..221]
gi\|39951937, gi\|... - gi\|39951937\|ref\|XP_363685.1\| hypothetical protein MGG_01611 [Magnaporthe grisea 70-15], gb\|EAA55960....	2.0E-63	[4..223]	[2..221]
gi\|125825005, gi... - gi\|57525923\|ref\|NP_001003546.1\| hypothetical protein LOC445152 [Danio rerio], gi\|50418488\|gb\|AAH7824...	8.0E-62	[22..223]	[2..203]

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Predicted Domain #1

Region A:
Residues: [1-223]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEEVDFLGQ DSDGGSEEVV LTPAELIERL EQAWMNEKFA PELLESKPEI VECVMEQLEH  60
   61 MEENLRRAKR EDLKVSIHQM EMERIRYVLS SYLRCRLMKI EKFFPHVLEK EKTRPEGEPS 120
  121 SLSPEELAFA REFMANTESY LKNVALKHMP PNLQKVDLFR AVPKPDLDSY VFLRVRERQE 180
  181 NILVEPDTDE QRDYVIDLEK GSQHLIRYKT IAPLVASGAV QLI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	79.69897
Match:	2e9xD
Description:	No description for 2e9xD was found.

Predicted functions:

Term	Confidence	Notes
3'-5' DNA helicase activity	3.30007058745861	bayes_pls_golite062009
DNA helicase activity	2.7662250039458	bayes_pls_golite062009
binding	1.86366637427031	bayes_pls_golite062009
protein binding	1.52285169518311	bayes_pls_golite062009
transcription regulator activity	1.2336233528067	bayes_pls_golite062009
helicase activity	1.2110072302388	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.406116199163083	bayes_pls_golite062009
pyrophosphatase activity	0.350000641617868	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.33576520693158	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.333445385039412	bayes_pls_golite062009
catalytic activity	0.161911144249814	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: