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View Structure Prediction Details

Protein: DHX30
Organism: Homo sapiens
Length: 1194 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DHX30.

Description E-value Query
Range
Subject
Range
gi|40788976 - gi|40788976|dbj|BAA74913.2| KIAA0890 protein [Homo sapiens]
0.0 [1..1194] [17..1210]
gi|114586612, gi... - gi|114586612|ref|XP_001155364.1| PREDICTED: DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 6 [Pan...
0.0 [1..1194] [1..1194]
gi|13111310 - gi|13111310|dbj|BAB32789.1| HELG [Mus musculus musculus]
DHX30_MOUSE - Putative ATP-dependent RNA helicase DHX30 OS=Mus musculus GN=Dhx30 PE=1 SV=1
0.0 [1..1194] [24..1217]
DHX30_PONPY - Putative ATP-dependent RNA helicase DHX30 - Pongo pygmaeus (Orangutan)
DHX30_PONAB - Putative ATP-dependent RNA helicase DHX30 OS=Pongo abelii GN=DHX30 PE=2 SV=1
0.0 [1..1194] [1..1194]
DHX30_RAT - Putative ATP-dependent RNA helicase DHX30 OS=Rattus norvegicus GN=Dhx30 PE=1 SV=1
0.0 [1..1194] [1..1194]
gi|109040949 - gi|109040949|ref|XP_001113204.1| PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box polypeptide 30 iso...
0.0 [1..1194] [1..1194]
gi|73985688 - gi|73985688|ref|XP_533844.2| PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform...
0.0 [1..1194] [1..1194]

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Predicted Domain #1
Region A:
Residues: [1-221]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSLDSFRKD RAQHRQRQCK LPPPRLPPMC VNPTPGGTIS RASRDLLKEF PQPKNLLNSV  60
   61 IGRALGISHA KDKLVYVHTN GPKKKKVTLH IKWPKSVEVE GYGSKKIDAE RQAAAAACQL 120
  121 FKGWGLLGPR NELFDAAKYR VLADRFGSPA DSWWRPEPTM PPTSWRQLNP ESIRPGGPGG 180
  181 LSRSLGREEE EDEEEELEEG TIDVTDFLSM TQQDSHAPLR D

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.69897
Match: 2db2A
Description: No description for 2db2A was found.

Predicted Domain #2
Region A:
Residues: [222-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRGSSFEMTD DDSAIRALTQ FPLPKNLLAK VIQIATSSST AKNLMQFHTV GTKTKLSTLT  60
   61 LLWPCPMTFV AKGRRKAEAE NKAAALACKK LKSLGLVDRN NEPLTHAMYN LASLRELGE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 5.37
Match: 2db2A
Description: No description for 2db2A was found.

Predicted Domain #3
Region A:
Residues: [341-404]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQRRPCTIQV PEPILRKIET FLNHYPVESS WIAPELRLQS DDILPLGKDS GPLSDPITGK  60
   61 PYVP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [405-1034]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLEAEEVRLS QSLLELWRRR GPVWQEAPQL PVDPHRDTIL NAIEQHPVVV ISGDTGCGKT  60
   61 TRIPQLLLER YVTEGRGARC NVIITQPRRI SAVSVAQRVS HELGPSLRRN VGFQVRLESK 120
  121 PPSRGGALLF CTVGILLRKL QSNPSLEGVS HVIVDEVHER DVNTDFLLIL LKGLQRLNPA 180
  181 LRLVLMSATG DNERFSRYFG GCPVIKVPGF MYPVKEHYLE DILAKLGKHQ YLHRHRHHES 240
  241 EDECALDLDL VTDLVLHIDA RGEPGGILCF LPGWQEIKGV QQRLQEALGM HESKYLILPV 300
  301 HSNIPMMDQK AIFQQPPVGV RKIVLATNIA ETSITINDIV HVVDSGLHKE ERYDLKTKVS 360
  361 CLETVWVSRA NVIQRRGRAG RCQSGFAYHL FPRSRLEKMV PFQVPEILRT PLENLVLQAK 420
  421 IHMPEKTAVE FLSKAVDSPN IKAVDEAVIL LQEIGVLDQR EYLTTLGQRL AHISTDPRLA 480
  481 KAIVLAAIFR CLHPLLVVVS CLTRDPFSSS LQNRAEVDKV KALLSHDSGS DHLAFVRAVA 540
  541 GWEEVLRWQD RSSRENYLEE NLLYAPSLRF IHGLIKQFSE NIYEAFLVGK PSDCTLASAQ 600
  601 CNEYSEEEEL VKGVLMAGLY PNLIQVRQGK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.69897
Match: 2p6rA
Description: No description for 2p6rA was found.

Predicted functions:

Term Confidence Notes
4.704140727858 bayes_pls_golite062009
binding 2.4974940028864 bayes_pls_golite062009
RNA binding 2.29590582680214 bayes_pls_golite062009
structural constituent of ribosome 1.57653963868443 bayes_pls_golite062009
RNA helicase activity 1.42791449104435 bayes_pls_golite062009
nucleic acid binding 1.41477043612798 bayes_pls_golite062009
RNA-dependent ATPase activity 1.39335733374328 bayes_pls_golite062009
ATP-dependent RNA helicase activity 1.36724390116598 bayes_pls_golite062009
DNA binding 1.11699929651302 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
transcription regulator activity 0.989226939888218 bayes_pls_golite062009
hydrolase activity 0.770112659770838 bayes_pls_golite062009
mRNA binding 0.76699944561918 bayes_pls_golite062009
helicase activity 0.6191010101321 bayes_pls_golite062009
structural molecule activity 0.596382945962261 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.461763181659193 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.458831409927227 bayes_pls_golite062009
pyrophosphatase activity 0.455976987338331 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.422944846459286 bayes_pls_golite062009
snRNA binding 0.418985924846052 bayes_pls_golite062009
protein binding 0.378225828131122 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
ATP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
translation release factor activity 0.178286731022211 bayes_pls_golite062009
translation termination factor activity 0.151456842619444 bayes_pls_golite062009
nucleotide binding 0.114848452385726 bayes_pls_golite062009
purine nucleotide binding 0.10713474095071 bayes_pls_golite062009
purine ribonucleotide binding 0.0916519414118148 bayes_pls_golite062009
ribonucleotide binding 0.0915913646217636 bayes_pls_golite062009
transcription factor activity 0.0434163635422169 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [1035-1194]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTRQGKFKPN SVTYRTKSGN ILLHKSTINR EATRLRSRWL TYFMAVKSNG SVFVRDSSQV  60
   61 HPLAVLLLTD GDVHIRDDGR RATISLSDSD LLRLEGDSRT VRLLKELRRA LGRMVERSLR 120
  121 SELAALPPSV QEEHGQLLAL LAELLRGPCG SFDVRKTADD 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle