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View Structure Prediction Details

Protein: DHX15
Organism: Homo sapiens
Length: 795 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DHX15.

Description E-value Query
Range		 Subject
Range
DHX15_PONPY - Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 - Pongo pygmaeus (Orangutan)
DHX15_PONAB - Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Pongo abelii GN=DHX15 PE=2 SV=2
 0.0 [1..795] [1..795]
gi|73951633 - gi|73951633|ref|XP_851535.1| PREDICTED: similar to Putative pre-mRNA splicing factor RNA helicase (D...
 0.0 [1..795] [1..795]
ENSCJAT00000025472 - null
gi|109073861 - gi|109073861|ref|XP_001106067.1| PREDICTED: DEAH (Asp-Glu-Ala-His) box polypeptide 15 isoform 5 [Mac...
 0.0 [1..795] [1..795]
gi|146186531, gi... - gi|76619677|ref|XP_870079.1| PREDICTED: similar to Putative pre-mRNA-splicing factor ATP-dependent R...
 0.0 [1..795] [1..795]
DHX15_MOUSE - Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Mus musculus GN=Dhx15 PE=1 SV=2
 0.0 [1..795] [1..795]
gi|149047227, gi... - gi|34878065|ref|XP_214053.2| PREDICTED: similar to Putative pre-mRNA-splicing factor ATP-dependent R...
 0.0 [1..795] [1..795]

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Predicted Domain #1
Region A:
Residues: [1-120] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKRHRLDLG EDYPSGKKRA GTDGKDRDRD RDREDRSKDR DRERDRGDRE REREKEKEKE  60
   61 LRASTNAMLI SAGLPPLKAS HSAHSTHSAH STHSTHSAHS THAGHAGHTS LPQCINPFTN 120
  121

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.69897
Match: 2db3A
Description: No description for 2db3A was found.

Predicted Domain #2
Region A:
Residues: [121-795] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPHTPRYYDI LKKRLQLPVW EYKDRFTDIL VRHQSFVLVG ETGSGKTTQI PQWCVEYMRS  60
   61 LPGPKRGVAC TQPRRVAAMS VAQRVADEMD VMLGQEVGYS IRFEDCSSAK TILKYMTDGM 120
  121 LLREAMNDPL LERYGVIILD EAHERTLATD ILMGVLKEVV RQRSDLKVIV MSATLDAGKF 180
  181 QIYFDNCPLL TIPGRTHPVE IFYTPEPERD YLEAAIRTVI QIHMCEEEEG DLLLFLTGQE 240
  241 EIDEACKRIK REVDDLGPEV GDIKIIPLYS TLPPQQQQRI FEPPPPKKQN GAIGRKVVVS 300
  301 TNIAETSLTI DGVVFVIDPG FAKQKVYNPR IRVESLLVTA ISKASAQQRA GRAGRTRPGK 360
  361 CFRLYTEKAY KTEMQDNTYP EILRSNLGSV VLQLKKLGID DLVHFDFMDP PAPETLMRAL 420
  421 ELLNYLAALN DDGDLTELGS MMAEFPLDPQ LAKMVIASCD YNCSNEVLSI TAMLSVPQCF 480
  481 VRPTEAKKAA DEAKMRFAHI DGDHLTLLNV YHAFKQNHES VQWCYDNFIN YRSLMSADNV 540
  541 RQQLSRIMDR FNLPRRSTDF TSRDYYINIR KALVTGYFMQ VAHLERTGHY LTVKDNQVVQ 600
  601 LHPSTVLDHK PEWVLYNEFV LTTKNYIRTC TDIKPEWLVK IAPQYYDMSN FPQCEAKRQL 660
  661 DRIIAKLQSK EYSQY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.154902
Match: 2p6rA
Description: No description for 2p6rA was found.

Predicted functions:

Term Confidence Notes
4.704140727858 bayes_pls_golite062009
binding 2.44689197844883 bayes_pls_golite062009
RNA binding 2.29590582680214 bayes_pls_golite062009
structural constituent of ribosome 1.57653963868443 bayes_pls_golite062009
RNA helicase activity 1.42791449104435 bayes_pls_golite062009
nucleic acid binding 1.41477043612798 bayes_pls_golite062009
RNA-dependent ATPase activity 1.39335733374328 bayes_pls_golite062009
ATP-dependent RNA helicase activity 1.36724390116598 bayes_pls_golite062009
DNA binding 1.11699929651302 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
transcription regulator activity 0.989226939888218 bayes_pls_golite062009
mRNA binding 0.76699944561918 bayes_pls_golite062009
helicase activity 0.6191010101321 bayes_pls_golite062009
motor activity 0.61636596887462 bayes_pls_golite062009
structural molecule activity 0.596382945962261 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.461763181659193 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.458831409927227 bayes_pls_golite062009
pyrophosphatase activity 0.455976987338331 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.422944846459286 bayes_pls_golite062009
snRNA binding 0.418985924846052 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.338958888186454 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
ATP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
translation release factor activity 0.178286731022211 bayes_pls_golite062009
translation termination factor activity 0.151456842619444 bayes_pls_golite062009
nucleotide binding 0.114848452385726 bayes_pls_golite062009
purine nucleotide binding 0.10713474095071 bayes_pls_golite062009
purine ribonucleotide binding 0.0916519414118148 bayes_pls_golite062009
ribonucleotide binding 0.0915913646217636 bayes_pls_golite062009
protein binding 0.071010918255742 bayes_pls_golite062009
transcription factor activity 0.0434163635422169 bayes_pls_golite062009
cytoskeletal protein binding 0.0272673919333979 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle