| Protein: | XIAP |
| Organism: | Homo sapiens |
| Length: | 497 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for XIAP.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..497] | [119..615] |
|
|
0.0 | [1..497] | [1..497] |
|
|
0.0 | [1..497] | [1..497] |
|
|
0.0 | [1..497] | [1..497] |
|
|
0.0 | [1..497] | [1..496] |
|
|
0.0 | [1..497] | [1..496] |
|
Region A: Residues: [1-117] |
1 11 21 31 41 51
| | | | | |
1 MTFNSFEGSK TCVPADINKE EEFVEEFNRL KTFANFPSGS PVSASTLARA GFLYTGEGDT 60
61 VRCFSCHAAV DRWQYGDSAV GRHRKVSPNC RFINGFYLEN SATQSTNSGI QNGQYKV
|
| Detection Method: |  |
| Confidence: | 24.39794 |
| Match: | 1f9xA |
| Description: | BIR domains of XIAP |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| caspase inhibitor activity | 3.37793799691411 | bayes_pls_golite062009 |
| protein binding | 2.82801305666365 | bayes_pls_golite062009 |
| binding | 2.82472291325192 | bayes_pls_golite062009 |
| caspase regulator activity | 2.78624473612776 | bayes_pls_golite062009 |
| cysteine-type endopeptidase inhibitor activity | 2.43952820346737 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.24291003560785 | bayes_pls_golite062009 |
| enzyme inhibitor activity | 1.18464294370673 | bayes_pls_golite062009 |
| microtubule binding | 1.03349057074077 | bayes_pls_golite062009 |
| tubulin binding | 1.0137804715367 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.515008648709161 | bayes_pls_golite062009 |
| protein dimerization activity | 0.204341973906209 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 0.0431703651486497 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 0.0242766345667098 | bayes_pls_golite062009 |
| cofactor binding | 0.0023150693787124 | bayes_pls_golite062009 |
|
Region A: Residues: [118-255] |
1 11 21 31 41 51
| | | | | |
1 ENYLGSRDHF ALDRPSETHA DYLLRTGQVV DISDTIYPRN PAMYSEEARL KSFQNWPDYA 60
61 HLTPRELASA GLYYTGIGDQ VQCFCCGGKL KNWEPCDRAW SEHRRHFPNC FFVLGRNLNI 120
121 RSESDAVSSD RNFPNSTN
|
| Detection Method: | |
| Confidence: | 34.221849 |
| Match: | 1i3oE |
| Description: | BIR domains of XIAP |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| caspase inhibitor activity | 3.37793799691411 | bayes_pls_golite062009 |
| protein binding | 2.82801305666365 | bayes_pls_golite062009 |
| binding | 2.82472291325192 | bayes_pls_golite062009 |
| caspase regulator activity | 2.78624473612776 | bayes_pls_golite062009 |
| cysteine-type endopeptidase inhibitor activity | 2.43952820346737 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.24291003560785 | bayes_pls_golite062009 |
| enzyme inhibitor activity | 1.18464294370673 | bayes_pls_golite062009 |
| microtubule binding | 1.03349057074077 | bayes_pls_golite062009 |
| tubulin binding | 1.0137804715367 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.515008648709161 | bayes_pls_golite062009 |
| protein dimerization activity | 0.204341973906209 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 0.0431703651486497 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 0.0242766345667098 | bayes_pls_golite062009 |
| cofactor binding | 0.0023150693787124 | bayes_pls_golite062009 |
|
Region A: Residues: [256-497] |
1 11 21 31 41 51
| | | | | |
1 LPRNPSMADY EARIFTFGTW IYSVNKEQLA RAGFYALGEG DKVKCFHCGG GLTDWKPSED 60
61 PWEQHAKWYP GCKYLLEQKG QEYINNIHLT HSLEECLVRT TEKTPSLTRR IDDTIFQNPM 120
121 VQEAIRMGFS FKDIKKIMEE KIQISGSNYK SLEVLVADLV NAQKDSMQDE SSQTSLQKEI 180
181 STEEQLRRLQ EEKLCKICMD RNIAIVFVPC GHLVTCKQCA EAVDKCPMCY TVITFKQKIF 240
241 MS
|
| Detection Method: | |
| Confidence: | 17.09691 |
| Match: | 1fbvA |
| Description: | Cbl; N-terminal domain of cbl (N-cbl); CBL |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein binding | 3.19631993182765 | bayes_pls_golite062009 |
| binding | 3.12724619324809 | bayes_pls_golite062009 |
| molecular transducer activity | 2.92323609459085 | bayes_pls_golite062009 |
| signal transducer activity | 2.92323609459085 | bayes_pls_golite062009 |
| molecular adaptor activity | 1.81145713371725 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 1.59474164216385 | bayes_pls_golite062009 |
| insulin receptor binding | 1.18707666182719 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.11378356087757 | bayes_pls_golite062009 |
| receptor binding | 1.09099343809921 | bayes_pls_golite062009 |
| calcium ion binding | 1.03474411638676 | bayes_pls_golite062009 |
| protein complex binding | 0.89751976248113 | bayes_pls_golite062009 |
| protein binding, bridging | 0.83823250804321 | bayes_pls_golite062009 |
| calcium-dependent protein binding | 0.551187568015903 | bayes_pls_golite062009 |
| transcription regulator activity | 0.540818657754841 | bayes_pls_golite062009 |
| structural constituent of muscle | 0.36302486156653 | bayes_pls_golite062009 |
| SH2 domain binding | 0.353553274217716 | bayes_pls_golite062009 |
| nucleic acid binding | 0.352421112301971 | bayes_pls_golite062009 |
| DNA binding | 0.281643350069021 | bayes_pls_golite062009 |
| structural molecule activity | 0.234626449126289 | bayes_pls_golite062009 |
| phosphoprotein binding | 0.16798254471727 | bayes_pls_golite062009 |
| actin binding | 0.113835617777946 | bayes_pls_golite062009 |
