| Protein: | PHF21A |
| Organism: | Homo sapiens |
| Length: | 680 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PHF21A.
| Description | E-value | Query Range |
Subject Range |
|
|
2.0E-57 | [1..680] | [1..687] |
|
|
4.0E-57 | [1..680] | [1..680] |
|
|
1.0E-56 | [1..680] | [1..681] |
|
|
2.0E-55 | [1..680] | [2..635] |
|
|
2.0E-55 | [1..680] | [1..694] |
|
|
3.0E-54 | [1..680] | [1..682] |
|
Region A: Residues: [1-251] |
1 11 21 31 41 51
| | | | | |
1 MELQTLQEAL KVEIQVHQKL VAQMKQDPQN ADLKKQLHEL QAKITALSEK QKRVVEQLRK 60
61 NLIVKQEQPD KFQIQPLPQS ENKLQTAQQQ PLQQLQQQQQ YHHHHAQQSA AASPNLTASQ 120
121 KTVTTASMIT TKTLPLVLKA ATATMPASVV GQRPTIAMVT AINSQKAVLS TDVQNTPVNL 180
181 QTSSKVTGPG AEAVQIVAKN TVTLVQATPP QPIKVPQFIP PPRLTPRPNF LPQVRPKPVA 240
241 QNNIPIAPAP P
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [252-483] |
1 11 21 31 41 51
| | | | | |
1 PMLAAPQLIQ RPVMLTKFTP TTLPTSQNSI HPVRVVNGQT ATIAKTFPMA QLTSIVIATP 60
61 GTRLAGPQTV QLSKPSLEKQ TVKSHTETDE KQTESRTITP PAAPKPKREE NPQKLAFMVS 120
121 LGLVTHDHLE EIQSKRQERK RRTTANPVYS GAVFEPERKK SAVTYLNSTM HPGTRKRGRP 180
181 PKYNAVLGFG ALTPTSPQSS HPDSPENEKT ETTFTFPAPV QPVSLPSPTS TD
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [484-550] |
1 11 21 31 41 51
| | | | | |
1 GDIHEDFCSV CRKSGQLLMC DTCSRVYHLD CLDPPLKTIP KGMWICPRCQ DQMLKKEEAI 60
61 PWPGTLA
|
| Detection Method: | |
| Confidence: | 10.69897 |
| Match: | 2puyA |
| Description: | No description for 2puyA was found. |
|
Region A: Residues: [551-680] |
1 11 21 31 41 51
| | | | | |
1 IVHSYIAYKA AKEEEKQKLL KWSSDLKQER EQLEQKVKQL SNSISKCMEM KNTILARQKE 60
61 MHSSLEKVKQ LIRLIHGIDL SKPVDSEATV GAISNGPDCT PPANAATSTP APSPSSQSCT 120
121 ANCNQGEETK
|
| Detection Method: | |
| Confidence: | 3.045757 |
| Match: | 2cotA |
| Description: | Solution structure of the first and second zf-C2H2 domain of Zinc finger protein 435 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 4.70988788192472 | bayes_pls_golite062009 |
| nucleic acid binding | 4.58713908116892 | bayes_pls_golite062009 |
| DNA binding | 4.56219307357342 | bayes_pls_golite062009 |
| transcription factor activity | 3.50954949535763 | bayes_pls_golite062009 |
| transcription repressor activity | 3.27542149084008 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 3.22082323675675 | bayes_pls_golite062009 |
| binding | 3.10743787485868 | bayes_pls_golite062009 |
| transcription activator activity | 2.19952417915035 | bayes_pls_golite062009 |
| chromatin binding | 2.18464662431232 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.63161912031789 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.42975942698743 | bayes_pls_golite062009 |
| transcription factor binding | 1.39608963544799 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.34049786451995 | bayes_pls_golite062009 |
| protein binding | 1.00484935878505 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.912796194488319 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.77874411480713 | bayes_pls_golite062009 |
| catalytic activity | 0.245893663605433 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.240825841910931 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.0129353639725593 | bayes_pls_golite062009 |
