| Protein: | LDHB |
| Organism: | Homo sapiens |
| Length: | 334 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LDHB.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..333] | [30..361] |
|
|
0.0 | [1..333] | [30..361] |
|
|
0.0 | [1..333] | [1..332] |
|
|
0.0 | [1..334] | [1..333] |
|
|
0.0 | [1..333] | [1..332] |
|
|
0.0 | [1..333] | [1..332] |
|
|
0.0 | [1..333] | [1..332] |
|
Region A: Residues: [1-334] |
1 11 21 31 41 51
| | | | | |
1 MATLKEKLIA PVAEEEATVP NNKITVVGVG QVGMACAISI LGKSLADELA LVDVLEDKLK 60
61 GEMMDLQHGS LFLQTPKIVA DKDYSVTANS KIVVVTAGVR QQEGESRLNL VQRNVNVFKF 120
121 IIPQIVKYSP DCIIIVVSNP VDILTYVTWK LSGLPKHRVI GSGCNLDSAR FRYLMAEKLG 180
181 IHPSSCHGWI LGEHGDSSVA VWSGVNVAGV SLQELNPEMG TDNDSENWKE VHKMVVESAY 240
241 EVIKLKGYTN WAIGLSVADL IESMLKNLSR IHPVSTMVKG MYGIENEVFL SLPCILNARG 300
301 LTSVINQKLK DDEVAQLKKS ADTLWDIQKD LKDL
|
| Detection Method: |  |
| Confidence: | 104.0 |
| Match: | 1t2fA |
| Description: | Human B lactate dehydrogenase complexed with NAD+ and 4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| L-malate dehydrogenase activity | 5.35837481826138 | bayes_pls_golite062009 |
| lactate dehydrogenase activity | 4.66418715735914 | bayes_pls_golite062009 |
| malate dehydrogenase activity | 3.75347253996971 | bayes_pls_golite062009 |
| oxidoreductase activity | 2.75947908917144 | bayes_pls_golite062009 |
| L-lactate dehydrogenase activity | 2.59062377380589 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on CH-OH group of donors | 2.58076782195922 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 1.88605255677599 | bayes_pls_golite062009 |
| binding | 1.76718756313666 | bayes_pls_golite062009 |
| catalytic activity | 1.67029398049886 | bayes_pls_golite062009 |
| protein binding | 1.47646217957458 | bayes_pls_golite062009 |
| NAD or NADH binding | 1.32276254629683 | bayes_pls_golite062009 |
| alcohol dehydrogenase (NAD) activity | 1.27032644348698 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 1.22444609393125 | bayes_pls_golite062009 |
| retinol dehydrogenase activity | 1.16811519855038 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor | 0.91702493082811 | bayes_pls_golite062009 |
| transferase activity, transferring acyl groups | 0.788034697021177 | bayes_pls_golite062009 |
| alcohol dehydrogenase activity, zinc-dependent | 0.729242797855749 | bayes_pls_golite062009 |
| fatty acid synthase activity | 0.714637370305282 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 0.621273823467575 | bayes_pls_golite062009 |
| coenzyme binding | 0.59785037604907 | bayes_pls_golite062009 |
| DNA binding | 0.525227236870065 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 0.523513694229008 | bayes_pls_golite062009 |
| nucleic acid binding | 0.459537641913493 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors | 0.216422278300306 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on NADH or NADPH | 0.19685680097448 | bayes_pls_golite062009 |
| 3-oxoacyl-[acyl-carrier-protein] reductase activity | 0.192594057004213 | bayes_pls_golite062009 |
| transcription regulator activity | 0.177044638410302 | bayes_pls_golite062009 |
| signal transducer activity | 0.0433763403499039 | bayes_pls_golite062009 |
| molecular transducer activity | 0.0433763403499039 | bayes_pls_golite062009 |
