| Protein: | AMFR |
| Organism: | Homo sapiens |
| Length: | 643 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AMFR.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..643] | [1..643] |
|
|
0.0 | [1..643] | [1..643] |
|
|
0.0 | [3..643] | [151..787] |
|
|
0.0 | [1..643] | [1..645] |
|
|
0.0 | [1..642] | [1..634] |
|
|
0.0 | [1..642] | [1..633] |
|
Region A: Residues: [1-134] |
1 11 21 31 41 51
| | | | | |
1 MPLLFLERFP WPSLRTYTGL SGLALLGTII SAYRALSQPE AGPGEPDQLT ASLQPEPPAP 60
61 ARPSAGGPRA RDVAQYLLSD SLFVWVLVNT ACCVLMLVAK LIQCIVFGPL RVSERQHLKD 120
121 KFWNFIFYKF IFIF
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [135-401] |
1 11 21 31 41 51
| | | | | |
1 GVLNVQTVEE VVMWCLWFAG LVFLHLMVQL CKDRFEYLSF SPTTPMSSHG RVLSLLVAML 60
61 LSCCGLAAVC SITGYTHGMH TLAFMAAESL LVTVRTAHVI LRYVIHLWDL NHEGTWEGKG 120
121 TYVYYTDFVM ELTLLSLDLM HHIHMLLFGN IWLSMASLVI FMQLRYLFHE VQRRIRRHKN 180
181 YLRVVGNMEA RFAVATPEEL AVNNDDCAIC WDSMQAARKL PCGHLFHNSC LRSWLEQDTS 240
241 CPTCRMSLNI ADNNRVREEH QGENLDE
|
| Detection Method: | |
| Confidence: | 24.39794 |
| Match: | 1fbvA |
| Description: | Cbl; N-terminal domain of cbl (N-cbl); CBL |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| molecular transducer activity | 3.58651960433016 | bayes_pls_golite062009 |
| signal transducer activity | 3.58651960433016 | bayes_pls_golite062009 |
| binding | 3.12724619324809 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 2.53071837898279 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 2.35007226898734 | bayes_pls_golite062009 |
| protein binding | 2.14586566310919 | bayes_pls_golite062009 |
| molecular adaptor activity | 1.81145713371725 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 1.60687631865164 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 1.59474164216385 | bayes_pls_golite062009 |
| ubiquitin-ubiquitin ligase activity | 1.37401357060257 | bayes_pls_golite062009 |
| small conjugating protein-specific protease activity | 1.2126425713931 | bayes_pls_golite062009 |
| calcium ion binding | 1.03474411638676 | bayes_pls_golite062009 |
| ubiquitin-specific protease activity | 1.03469202541773 | bayes_pls_golite062009 |
| receptor binding | 1.02111138016453 | bayes_pls_golite062009 |
| insulin receptor binding | 0.998938018700239 | bayes_pls_golite062009 |
| protein binding, bridging | 0.83823250804321 | bayes_pls_golite062009 |
| S100 alpha binding | 0.695694593922059 | bayes_pls_golite062009 |
| transcription regulator activity | 0.540818657754841 | bayes_pls_golite062009 |
| phosphoprotein binding | 0.53070890116366 | bayes_pls_golite062009 |
| nucleic acid binding | 0.476094076158571 | bayes_pls_golite062009 |
| protein kinase activity | 0.373245013550244 | bayes_pls_golite062009 |
| hydrolase activity | 0.365893102981186 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.293268642733772 | bayes_pls_golite062009 |
| DNA binding | 0.281643350069021 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.27738240687034 | bayes_pls_golite062009 |
| ubiquitin thiolesterase activity | 0.265769062717221 | bayes_pls_golite062009 |
| structural constituent of muscle | 0.23313435855689 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.205769810664775 | bayes_pls_golite062009 |
| channel activity | 0.205769810664775 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.202021526297279 | bayes_pls_golite062009 |
| kinase activity | 0.193243470329802 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.182737303659095 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.16976955164497 | bayes_pls_golite062009 |
| ion channel activity | 0.0949210510895822 | bayes_pls_golite062009 |
| gated channel activity | 0.0709126830279607 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 0.0099972847734251 | bayes_pls_golite062009 |
|
Region A: Residues: [402-495] |
1 11 21 31 41 51
| | | | | |
1 NLVPVAAAEG RPRLNQHNHF FHFDGSRIAS WLPSFSVEVM HTTNILGITQ ASNSQLNAMA 60
61 HQIQEMFPQV PYHLVLQDLQ LTRSVEITTD NILE
|
| Detection Method: | |
| Confidence: | 3.15 |
| Match: | 2ekfA |
| Description: | No description for 2ekfA was found. |
|
Region A: Residues: [496-643] |
1 11 21 31 41 51
| | | | | |
1 GRIQVPFPTQ RSDSIRPALN SPVERPSSDQ EEGETSAQTE RVPLDLSPRL EETLDFGEVE 60
61 VEPSEVEDFE ARGSRFSKSA DERQRMLVQR KDELLQQARK RFLNKSSEDD AASESFLPSE 120
121 GASSDPVTLR RRMLAAAAER RLQKQQTS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
