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View Structure Prediction Details

Protein: ELL
Organism: Homo sapiens
Length: 621 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ELL.

Description E-value Query
Range
Subject
Range
gi|76620744 - gi|76620744|ref|XP_583044.2| PREDICTED: similar to RNA polymerase II elongation factor ELL (Eleven-n...
0.0 [1..621] [1..616]
gi|73986120 - gi|73986120|ref|XP_541936.2| PREDICTED: similar to RNA polymerase II elongation factor ELL (Eleven-n...
0.0 [1..621] [1..613]
gi|109503986 - gi|109503986|ref|XP_001070626.1| PREDICTED: similar to RNA polymerase II elongation factor ELL (Elev...
0.0 [1..621] [31..634]
gi|109078054 - gi|109078054|ref|XP_001094059.1| PREDICTED: elongation factor, RNA polymerase II, 2 isoform 2 [Macac...
0.0 [2..621] [7..640]
gi|61098133, gi|... - gi|61098133|ref|NP_001012865.1| elongation factor RNA polymerase II [Gallus gallus], gi|53128622|emb...
0.0 [1..616] [1..609]
gi|114599074 - gi|114599074|ref|XP_517646.2| PREDICTED: elongation factor, RNA polymerase II, 2 isoform 4 [Pan trog...
0.0 [3..620] [8..639]
ELL2 - elongation factor, RNA polymerase II, 2
gi|123981266, gi... - gi|123996099|gb|ABM85651.1| elongation factor, RNA polymerase II, 2 [synthetic construct], gi|123981...
0.0 [3..620] [8..639]

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Predicted Domain #1
Region A:
Residues: [1-131]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAALKEDRSY GLSCGRVSDG SKVSVFHVKL TDSALRAFES YRARQDSVSL RPSIRFQGSQ  60
   61 GHISIPQPDC PAEARTFSFY LSNIGRDNPQ GSFDCIQQYV SSHGEVHLDC LGSIQDKITV 120
  121 CATDDSYQKA R

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [132-290]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSMAQAEEET RSRSAIVIKA GGRYLGKKVQ FRKPAPGATD AVPSRKRATP INLASAIRKS  60
   61 GASAVSGGSG VSQRPFRDRV LHLLALRPYR KAELLLRLQK DGLTQADKDA LDGLLQQVAN 120
  121 MSAKDGTCTL QDCMYKDVQK DWPGYSEGDQ QLLKRVLVR

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.55
Match: 2doaA
Description: No description for 2doaA was found.

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.23858959608048 bayes_pls_golite062009
DNA binding 4.54024488199476 bayes_pls_golite062009
nucleic acid binding 4.30331577005505 bayes_pls_golite062009
binding 3.89976494610525 bayes_pls_golite062009
transcription factor activity 3.82269332595313 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.41045867230388 bayes_pls_golite062009
transcription activator activity 2.13702350917359 bayes_pls_golite062009
sequence-specific DNA binding 2.12567455635303 bayes_pls_golite062009
transcription repressor activity 1.9708626903609 bayes_pls_golite062009
transcription elongation regulator activity 1.75305601393584 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.976708325140011 bayes_pls_golite062009
transcription factor binding 0.752335897765285 bayes_pls_golite062009
protein binding 0.749376520208656 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.490809930581315 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [291-399]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLCQPQSTGS LLGDPAASSP PGERGRSASP PQKRLQPPDF IDPLANKKPR ISHFTQRAQP  60
   61 AVNGKLGVPN GREALLPTPG PPASTDTLSS STHLPPRLEP PRAHDPLAD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [400-491]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSNDLGHSGR DCEHGEAAAP APTVRLGLPL LTDCAQPSRP HGSPSRSKPK KKSKKHKDKE  60
   61 RAAEDKPRAQ LPDCAPATHA TPGAPADTPG LN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [492-621]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTCSVSSVPT STSETPDYLL KYAAISSSEQ RQSYKNDFNA EYSEYRDLHA RIERITRRFT  60
   61 QLDAQLRQLS QGSEEYETTR GQILQEYRKI KKTNTNYSQE KHRCEYLHSK LAHIKRLIAE 120
  121 YDQRQLQAWP 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.221849
Match: 1xawA
Description: crystal structure of the cytoplasmic distal C-terminal domain of occludin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle