| Protein: | HSF1 |
| Organism: | Homo sapiens |
| Length: | 529 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HSF1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..529] | [1..529] |
|
|
0.0 | [1..529] | [1..529] |
|
|
0.0 | [1..529] | [1..525] |
|
|
0.0 | [1..529] | [1..527] |
|
|
0.0 | [1..529] | [1..525] |
|
|
0.0 | [1..529] | [1..525] |
|
Region A: Residues: [1-117] |
1 11 21 31 41 51
| | | | | |
1 MDLPVGPGAA GPSNVPAFLT KLWTLVSDPD TDALICWSPS GNSFHVFDQG QFAKEVLPKY 60
61 FKHNNMASFV RQLNMYGFRK VVHIEQGGLV KPERDDTEFQ HPCFLRGQEQ LLENIKR
|
| Detection Method: |  |
| Confidence: | 37.69897 |
| Match: | 1hksA |
| Description: | SOLUTION STRUCTURE OF THE DNA-BINDING DOMAIN OF DROSOPHILA HEAT SHOCK TRANSCRIPTION FACTOR |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.55329976718261 | bayes_pls_golite062009 |
| DNA binding | 5.08959163553491 | bayes_pls_golite062009 |
| nucleic acid binding | 4.99681957904233 | bayes_pls_golite062009 |
| transcription factor activity | 4.33152142980289 | bayes_pls_golite062009 |
| transcription repressor activity | 3.85678231380989 | bayes_pls_golite062009 |
| transcription activator activity | 3.70589483230587 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 3.58179858678904 | bayes_pls_golite062009 |
| binding | 3.52874320222492 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.60738445921725 | bayes_pls_golite062009 |
| protein binding | 1.80415286835431 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.03021023030569 | bayes_pls_golite062009 |
| specific transcriptional repressor activity | 0.96257232341735 | bayes_pls_golite062009 |
| transcription factor binding | 0.85714789329232 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 0.66743181561551 | bayes_pls_golite062009 |
| NFAT protein binding | 0.59057750322522 | bayes_pls_golite062009 |
| transferase activity | 0.382878181629158 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.322180400748724 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.23177057841536 | bayes_pls_golite062009 |
|
Region A: Residues: [118-274] |
1 11 21 31 41 51
| | | | | |
1 KVTSVSTLKS EDIKIRQDSV TKLLTDVQLM KGKQECMDSK LLAMKHENEA LWREVASLRQ 60
61 KHAQQQKVVN KLIQFLISLV QSNRILGVKR KIPLMLNDSG SAHSMPKYSR QFSLEHVHGS 120
121 GPYSAPSPAY SSSSLYAPDA VASSGPIISD ITELAPA
|
| Detection Method: | |
| Confidence: | 9.721246 |
| Match: | PF00447.8 |
| Description: | No description for PF00447.8 was found. |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [275-366] |
1 11 21 31 41 51
| | | | | |
1 SPMASPGGSI DERPLSSSPL VRVKEEPPSP PQSPRVEEAS PGRPSSVDTL LSPTALIDSI 60
61 LRESEPAPAS VTALTDARGH TDTEGRPPSP PP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [367-529] |
1 11 21 31 41 51
| | | | | |
1 TSTPEKCLSV ACLDKNELSD HLDAMDSNLD NLQTMLSSHG FSVDTSALLD LFSPSVTVPD 60
61 MSLPDLDSSL ASIQELLSPQ EPPRPPEAEN SSPDSGKQLV HYTAQPLFLL DPGSVDTGSN 120
121 DLPVLFELGE GSYFSEGDGF AEDPTISLLT GSEPPKAKDP TVS
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
