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Protein Overview: HSF1_MOUSE

General Information:
Name(s) found: HSF1_MOUSE [Swiss-Prot]
Description(s) found:
Found 14 descriptions.
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  • Heat shock factor protein 1 OS=Mus musculus GN=Hsf1 PE=1 SV=2 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 525 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cytoplasm [IDA]
    pronucleus [IDA]
    protein complex [IPI]
    Biological Process: transcription [IEA]
    negative regulation of cell proliferation [IGI]
    spermatogenesis [IGI]
    regulation of transcription, DNA-dependent [IEA]
    regulation of transcription [IEA]
    embryonic process involved in female pregnancy [IMP]
    protein amino acid phosphorylation [IDA]
    defense response [UNKNOWN]
    response to stress [IEA]
    embryonic placenta development [IMP]
    positive regulation of multicellular organism growth [IMP]
    response to heat [IMP]
    in utero embryonic development [IMP]
    response to lipopolysaccharide [IMP]
    negative regulation of tumor necrosis factor production [IMP]
    Molecular Function: DNA binding [IDA]
    transcription factor activity [IEA]
    sequence-specific DNA binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLAVGPGAA GPSNVPAFLT KLWTLVSDPD TDALICWSPS GNSFHVFDQG QFAKEVLPKY  60
   61 FKHNNMASFV RQLNMYGFRK VVHIEQGGLV KPERDDTEFQ HPCFLRGQEQ LLENIKRKVT 120
  121 SVSTLKSEDI KIRQDSVTRL LTDVQLMKGK QECMDSKLLA MKHENEALWR EVASLRQKHA 180
  181 QQQKVVNKLI QFLISLVQSN RILGVKRKIP LMLSDSNSAH SVPKYGRQYS LEHVHGPGPY 240
  241 SAPSPAYSSS SLYSSDAVTS SGPIISDITE LAPTSPLASP GRSIDERPLS SSTLVRVKQE 300
  301 PPSPPHSPRV LEASPGRPSS MDTPLSPTAF IDSILRESEP TPAASNTAPM DTTGAQAPAL 360
  361 PTPSTPEKCL SVACLDKNEL SDHLDAMDSN LDNLQTMLTS HGFSVDTSAL LDLFSPSVTM 420
  421 PDMSLPDLDS SLASIQELLS PQEPPRPIEA ENSNPDSGKQ LVHYTAQPLF LLDPDAVDTG 480
  481 SSELPVLFEL GESSYFSEGD DYTDDPTISL LTGTEPHKAK DPTVS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle