| Protein: | HAND2 |
| Organism: | Homo sapiens |
| Length: | 217 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HAND2.
| Description | E-value | Query Range |
Subject Range |
|
|
7.0E-46 | [1..217] | [1..217] |
|
|
3.0E-42 | [1..217] | [1..210] |
|
|
5.0E-40 | [1..217] | [1..186] |
|
|
8.0E-40 | [1..217] | [1..205] |
|
|
4.0E-39 | [1..217] | [1..216] |
|
|
5.0E-38 | [1..217] | [1..180] |
|
Region A: Residues: [1-91] |
1 11 21 31 41 51
| | | | | |
1 MSLVGGFPHH PVVHHEGYPF AAAAAAAAAA AASRCSHEEN PYFHGWLIGH PEMSPPDYSM 60
61 ALSYSPEYAS GAAGLDHSHY GGVPPGAGPP G
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [92-217] |
1 11 21 31 41 51
| | | | | |
1 LGGPRPVKRR GTANRKERRR TQSINSAFAE LRECIPNVPA DTKLSKIKTL RLATSYIAYL 60
61 MDLLAKDDQN GEAEAFKAEI KKTDVKEEKR KKELNEILKS TVSSNDKKTK GRTGWPQHVW 120
121 ALELKQ
|
| Detection Method: | |
| Confidence: | 18.221849 |
| Match: | 1nkpA |
| Description: | Myc prot-oncogene protein |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.38658950816179 | bayes_pls_golite062009 |
| DNA binding | 5.18654839258297 | bayes_pls_golite062009 |
| nucleic acid binding | 5.05768805749761 | bayes_pls_golite062009 |
| transcription factor activity | 4.78039531631248 | bayes_pls_golite062009 |
| transcription activator activity | 3.87875547821718 | bayes_pls_golite062009 |
| binding | 3.81829206350975 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 3.42035985454056 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 3.39500382187264 | bayes_pls_golite062009 |
| protein binding | 2.64975291677725 | bayes_pls_golite062009 |
| transcription factor binding | 2.61163564741984 | bayes_pls_golite062009 |
| transcription repressor activity | 2.58751248599889 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 2.42306484786159 | bayes_pls_golite062009 |
| transcription corepressor activity | 2.03674713048499 | bayes_pls_golite062009 |
| promoter binding | 1.56457725225443 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.52770895937238 | bayes_pls_golite062009 |
| transcription coactivator activity | 1.39260472877067 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.53175615551166 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.3655541712365 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.29436315000437 | bayes_pls_golite062009 |
| protein dimerization activity | 0.20674648626116 | bayes_pls_golite062009 |
