YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|182705285, gi...
Organism:	Homo sapiens
Length:	444 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|182705285, gi....

Description	E-value	Query Range	Subject Range
gi\|48095525 - gi\|48095525\|ref\|XP_392313.1\| PREDICTED: similar to -Tubulin at 56D CG9277-PB, isoform B [Apis mellif...	0.0	[1..443]	[1..444]
gi\|157767470 - gi\|157767470\|ref\|XP_001667215.1\| Hypothetical protein CBG16137 [Caenorhabditis briggsae AF16] tbb-4 - tubulin beta chain status:Partially_confirmed UniProt:P41937 protein_id:CAA86310.1 gi\|39596183, gi\|... - gi\|39596183\|emb\|CAE69820.1\| Hypothetical protein CBG16137 [Caenorhabditis briggsae], gi\|187026681\|em...	0.0	[1..443]	[1..443]
gi\|74223737 - gi\|74223737\|dbj\|BAE28709.1\| unnamed protein product [Mus musculus]	0.0	[1..429]	[1..429]
gi\|91086093 - gi\|91086093\|ref\|XP_967267.1\| PREDICTED: similar to beta1-tubulin [Tribolium castaneum]	0.0	[1..443]	[1..444]
gi\|157132376, gi... - gi\|157132376\|ref\|XP_001656025.1\| tubulin beta chain [Aedes aegypti], gi\|108881720\|gb\|EAT45945.1\| tub...	0.0	[1..443]	[1..444]
gi\|73996516 - gi\|73996516\|ref\|XP_850665.1\| PREDICTED: similar to Tubulin alpha-2 chain (Alpha-tubulin 2) isoform 2...	0.0	[1..439]	[1..449]
gi\|115971215, gi... - gi\|72065171\|ref\|XP_791790.1\| PREDICTED: hypothetical protein [Strongylocentrotus purpuratus], gi\|115...	0.0	[1..430]	[1..430]

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Predicted Domain #1

Region A:
Residues: [1-444]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREIVLTQIG QCGNQIGAKF WEVISDEHAI DSAGTYHGDS HLQLERINVY YNEASGGRYV  60
   61 PRAVLVDLEP GTMDSVRSGP FGQVFRPDNF IFGQCGAGNN WAKGHYTEGA ELMESVMDVV 120
  121 RKEAESCDCL QGFQLTHSLG GGTGSGMGTL LLSKIREEYP DRIINTFSIL PSPKVSDTVV 180
  181 EPYNATLSVH QLIENADETF CIDNEALYDI CSKTLKLPTP TYGDLNHLVS ATMSGVTTCL 240
  241 RFPGQLNADL RKLAVNMVPF PRLHFFMPGF APLTSRGSQQ YRALTVAELT QQMFDAKNMM 300
  301 AACDPRHGRY LTAAAIFRGR MPMREVDEQM FNIQDKNSSY FADWLPNNVK TAVCDIPPRG 360
  361 LKMSATFIGN NTAIQELFKR VSEQFTAMFR RKAFLHWYTG EGMDEMEFTE AESNMNDLVS 420
  421 EYQQYQDATA EEEEDEEYAE EEVA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1ffxB
Description:	Tubulin:stathmin-like domain complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
structural constituent of cytoskeleton	4.04224160177678	bayes_pls_golite062009
structural molecule activity	3.32779015200848	bayes_pls_golite062009
tubulin binding	2.4432045213385	bayes_pls_golite062009
cytoskeletal protein binding	2.24606230377981	bayes_pls_golite062009
binding	2.00508289492248	bayes_pls_golite062009
GTPase activity	1.87512665946067	bayes_pls_golite062009
nucleoside-triphosphatase activity	1.77500173070686	bayes_pls_golite062009
pyrophosphatase activity	1.7017047947554	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.68267378160702	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.68038087466376	bayes_pls_golite062009
protein binding	1.60795853516357	bayes_pls_golite062009
MHC class I protein binding	1.46574865275013	bayes_pls_golite062009
gamma-tubulin binding	1.02742779831447	bayes_pls_golite062009
hydrolase activity	0.502038132260603	bayes_pls_golite062009
receptor binding	0.00945891657658993	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: