| Protein: | DLX2 |
| Organism: | Homo sapiens |
| Length: | 328 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DLX2.
| Description | E-value | Query Range |
Subject Range |
|
|
8.0E-27 | [1..217] | [218..437] |
|
|
9.0E-27 | [1..328] | [1..328] |
|
|
1.0E-25 | [12..221] | [1..216] |
|
|
5.0E-25 | [144..240] | [1..97] |
|
|
5.0E-25 | [143..224] | [11..92] |
|
|
6.0E-25 | [149..236] | [7..94] |
|
|
7.0E-25 | [88..243] | [76..231] |
|
|
7.0E-25 | [146..310] | [7..174] |
|
|
7.0E-25 | [147..239] | [3..95] |
|
|
8.0E-25 | [148..221] | [7..80] |
|
Region A: Residues: [1-112] |
1 11 21 31 41 51
| | | | | |
1 MTGVFDSLVA DMHSTQIAAS STYHQHQQPP SGGGAGPGGN SSSSSSLHKP QESPTLPVST 60
61 ATDSSYYTNQ QHPAGGGGGG GSPYAHMGSY QYQASGLNNV PYSAKSSYDL GY
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [113-226] |
1 11 21 31 41 51
| | | | | |
1 TAAYTSYAPY GTSSSPANNE PEKEDLEPEI RIVNGKPKKV RKPRTIYSSF QLAALQRRFQ 60
61 KTQYLALPER AELAASLGLT QTQVKIWFQN RRSKFKKMWK SGEIPSEQHP GASA
|
| Detection Method: | |
| Confidence: | 22.154902 |
| Match: | 1b72A |
| Description: | Homeobox protein hox-b1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.13863038737912 | bayes_pls_golite062009 |
| DNA binding | 4.66369707598026 | bayes_pls_golite062009 |
| nucleic acid binding | 4.51452285155271 | bayes_pls_golite062009 |
| transcription factor activity | 4.06706589695599 | bayes_pls_golite062009 |
| transcription repressor activity | 3.55154985983449 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 3.5139760613123 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 3.16896789933192 | bayes_pls_golite062009 |
| transcription activator activity | 3.10621734076555 | bayes_pls_golite062009 |
| binding | 3.02779747447702 | bayes_pls_golite062009 |
| protein binding | 1.88087411289001 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.73068440195944 | bayes_pls_golite062009 |
| chromatin binding | 1.68956710349366 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.49423102874486 | bayes_pls_golite062009 |
| transcription factor binding | 1.40653841901929 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.84983974758882 | bayes_pls_golite062009 |
|
Region A: Residues: [227-328] |
1 11 21 31 41 51
| | | | | |
1 SPPCASPPVS APASWDFGVP QRMAGGGGPG SGGSGAGSSG SSPSSAASAF LGNYPWYHQT 60
61 SGSASHLQAT APLLHPTQTP QPHHHHHHHG GGGAPVSAGT IF
|
| Detection Method: | |
| Confidence: | 1.0 |
| Match: | 2awzA |
| Description: | Hepatitis C Virus NS5b RNA Polymerase in complex with a covalent inhibitor (5h) |
Matching Structure (courtesy of the PDB): |
|
