YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: PAX7
Organism: Homo sapiens
Length: 520 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PAX7.

Description E-value Query
Range
Subject
Range
gi|76666870 - gi|76666870|ref|XP_877127.1| PREDICTED: similar to Paired box protein Pax-3 isoform 8 [Bos taurus]
2.0E-59 [1..268] [1..273]
gi|109477586, gi... - gi|109477586|ref|XP_001071787.1| PREDICTED: similar to paired box gene 7 [Rattus norvegicus], gi|109...
5.0E-58 [1..468] [1..466]
PAX7_MOUSE - Paired box protein Pax-7 OS=Mus musculus GN=Pax7 PE=1 SV=2
gi|162319578, gi... - gi|162319578|gb|AAI56885.1| Paired box gene 7 [synthetic construct], gi|162318458|gb|AAI56073.1| Pai...
1.0E-57 [1..468] [1..466]
gi|111307754, gi... - gi|7524359|ref|NP_039236.1| paired box 7 isoform 2 [Homo sapiens], gi|2570014|emb|CAA65521.1| PAX7 [...
2.0E-57 [1..520] [1..518]
gi|108998498 - gi|108998498|ref|XP_001091237.1| PREDICTED: similar to paired box gene 7 isoform 2 isoform 2 [Macaca...
3.0E-57 [1..520] [1..518]
gi|114554358 - gi|114554358|ref|XP_513156.2| PREDICTED: paired box gene 7 isoform 2 [Pan troglodytes]
2.0E-56 [1..520] [1..518]

Back

Predicted Domain #1
Region A:
Residues: [1-170]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAALPGTVPR MMRPAPGQNY PRTGFPLEVS TPLGQGRVNQ LGGVFINGRP LPNHIRHKIV  60
   61 EMAHHGIRPC VISRQLRVSH GCVSKILCRY QETGSIRPGA IGGSKPRQVA TPDVEKKIEE 120
  121 YKRENPGMFS WEIRDRLLKD GHCDRSTVPS GLVSSISRVL RIKFGKKEEE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.39794
Match: 1k78A
Description: Pax-5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
nucleic acid binding 4.51452285155271 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
transcription repressor activity 3.55154985983449 bayes_pls_golite062009
sequence-specific DNA binding 3.5139760613123 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.16896789933192 bayes_pls_golite062009
transcription activator activity 3.10621734076555 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
protein binding 1.88087411289001 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.73068440195944 bayes_pls_golite062009
chromatin binding 1.68956710349366 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.62096064323298 bayes_pls_golite062009
transcription corepressor activity 1.49423102874486 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
cytoskeletal protein binding 0.768149315604243 bayes_pls_golite062009
transcription coactivator activity 0.2679415219517 bayes_pls_golite062009
protein deacetylase activity 0.0943601066056998 bayes_pls_golite062009
actin binding 0.0864629297513302 bayes_pls_golite062009
histone deacetylase activity 0.0802156998596484 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [171-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEADKKEDDG EKKAKHSIDG ILGDKGNRLD EGSDVESEPD LPLKRKQRRS RTTFTAEQLE  60
   61 ELEKAFERTH YPDIYTREEL AQRTKLTEAR VQVWFSNRRA RWRKQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.0
Match: 1fjlA
Description: Paired protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
nucleic acid binding 4.51452285155271 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
transcription repressor activity 3.55154985983449 bayes_pls_golite062009
sequence-specific DNA binding 3.5139760613123 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.16896789933192 bayes_pls_golite062009
transcription activator activity 3.10621734076555 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
protein binding 1.88087411289001 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.73068440195944 bayes_pls_golite062009
chromatin binding 1.68956710349366 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.62096064323298 bayes_pls_golite062009
transcription corepressor activity 1.49423102874486 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
cytoskeletal protein binding 0.768149315604243 bayes_pls_golite062009
transcription coactivator activity 0.2679415219517 bayes_pls_golite062009
protein deacetylase activity 0.0943601066056998 bayes_pls_golite062009
actin binding 0.0864629297513302 bayes_pls_golite062009
histone deacetylase activity 0.0802156998596484 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [276-361]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGANQLAAFN HLLPGGFPPT GMPTLPPYQL PDSTYPTTTI SQDGGSTVHR PQPLPPSTMH  60
   61 QGGLAAAAAA ADTSSAYGAR HSFSSY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [362-520]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDSFMNPAAP SNHMNPVSNG LSPQVMSILG NPSAVPPQPQ ADFSISPLHG GLDSATSISA  60
   61 SCSQRADSIK PGDSLPTSQA YCPPTYSTTG YSVDPVAGYQ YGQYGQSECL VPWASPVPIP 120
  121 SPTPRASCLF MESYKVVSGW GMSISQMEKL KSSQMEQFT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle