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View Structure Prediction Details

Protein: FUN19
Organism: Saccharomyces cerevisiae
Length: 413 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FUN19.

Description E-value Query
Range
Subject
Range
gi|207348022 - gi|207348022|gb|EDZ74003.1| YAL034Cp-like protein [Saccharomyces cerevisiae AWRI1631]
FUN19 - Non-essential protein of unknown function; expression induced in response to heat stress
502.0 [0..1] [413..51]

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Predicted Domain #1
Region A:
Residues: [1-209]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLYSPESEK SQLNMNYIGK DDSQSIFRRL NQNLKASNNN NDSNKNGLNM SDYSNNSPYG  60
   61 RSYDVRINQN SQNNGNGCFS GSIDSLVDEH IIPSPPLSPK LESKISHNGS PRMASSVLVG 120
  121 STPKGAVENV LFVKPVWPNG LSRKRYRYAT YGFLSQYKIF SNLAQPYSKN IINRYNNLAY 180
  181 NARHKYSKYN DDMTPPPLPS SSSRLPSPL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [210-312]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASPNLNRQAR YNMRKQALYN NNLGKFESDT EWIPRKRKVY SPQRRTMTTS PHRAKKFSPS  60
   61 ASTPHTNIAS IEAIHDAPQY IPNVSWKKLP DYSPPLSTLP TDS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [313-413]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKSLKIEWKG SPMDLSTDPL RNELHPAELV LAQTLRLPCD LYLDSKRRLF LEKVYRLKKG  60
   61 LPFRRTDAQK ACRIDVNKAS RLFQAFEKVG WLQDSNFTKY L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.69897
Match: 2aqeA
Description: Structural and functional analysis of ada2 alpha swirm domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.61657063316558 bayes_pls_golite062009
DNA binding 3.20600447901865 bayes_pls_golite062009
nucleic acid binding 3.13775670276163 bayes_pls_golite062009
transcription factor activity 2.61318050866004 bayes_pls_golite062009
sequence-specific DNA binding 2.14408928200987 bayes_pls_golite062009
binding 2.12643314274039 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.77209608685482 bayes_pls_golite062009
transcription activator activity 1.75864690109096 bayes_pls_golite062009
protein binding 1.62529996900514 bayes_pls_golite062009
transcription repressor activity 0.605733396003465 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.380372494934551 bayes_pls_golite062009
chromatin binding 0.346262410069781 bayes_pls_golite062009
transcription factor binding 0.109547968922689 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle