| Protein: | TKL1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 680 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TKL1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..680] | [1..680] |
|
|
0.0 | [1..664] | [1..668] |
|
|
0.0 | [1..665] | [1..664] |
|
|
0.0 | [1..664] | [1..668] |
|
|
0.0 | [1..665] | [1..664] |
|
|
0.0 | [1..680] | [1..682] |
|
|
0.0 | [1..664] | [1..668] |
|
Region A: Residues: [1-128] |
1 11 21 31 41 51
| | | | | |
1 MTQFTDIDKL AVSTIRILAV DTVSKANSGH PGAPLGMAPA AHVLWSQMRM NPTNPDWINR 60
61 DRFVLSNGHA VALLYSMLHL TGYDLSIEDL KQFRQLGSRT PGHPEFELPG VEVTTGPLGQ 120
121 GISNAVGM
|
|
Region B: Residues: [148-310] |
1 11 21 31 41 51
| | | | | |
1 DNYTYVFLGD GCLQEGISSE ASSLAGHLKL GNLIAIYDDN KITIDGATSI SFDEDVAKRY 60
61 EAYGWEVLYV ENGNEDLAGI AKAIAQAKLS KDKPTLIKMT TTIGYGSLHA GSHSVHGAPL 120
121 KADDVKQLKS KFGFNPDKSF VVPQEVYDHY QKTILKPGVE ANN
|
| Detection Method: |  |
| Confidence: | 11000.0 |
| Match: | 1gpuA_ |
| Description: | Transketolase (TK), Pyr module; Transketolase (TK), PP module; Transketolase (TK), C-domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transketolase activity | 6.17852985073866 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | 2.93250853993668 | bayes_pls_golite062009 |
| pyruvate dehydrogenase activity | 2.81702263447118 | bayes_pls_golite062009 |
| pyruvate dehydrogenase (acetyl-transferring) activity | 2.6977837113283 | bayes_pls_golite062009 |
| transferase activity, transferring aldehyde or ketonic groups | 2.21959520697519 | bayes_pls_golite062009 |
| binding | 0.980920092099572 | bayes_pls_golite062009 |
| catalytic activity | 0.545407789079971 | bayes_pls_golite062009 |
| thiamin pyrophosphate binding | 0.297191393111081 | bayes_pls_golite062009 |
| acetolactate synthase activity | 0.173822256668691 | bayes_pls_golite062009 |
|
Region A: Residues: [129-147] |
1 11 21 31 41 51
| | | | | |
1 AMAQANLAAT YNKPGFTLS
|
|
Region B: Residues: [311-340] |
1 11 21 31 41 51
| | | | | |
1 KWNKLFSEYQ KKFPELGAEL ARRLSGQLPA
|
| Detection Method: | |
| Confidence: | 11000.0 |
| Match: | 1gpuA_ |
| Description: | Transketolase (TK), Pyr module; Transketolase (TK), PP module; Transketolase (TK), C-domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [341-366] |
1 11 21 31 41 51
| | | | | |
1 NWESKLPTYT AKDSAVATRK LSETVL
|
|
Region B: Residues: [465-680] |
1 11 21 31 41 51
| | | | | |
1 WVATHDSIGV GEDGPTHQPI ETLAHFRSLP NIQVWRPADG NEVSAAYKNS LESKHTPSII 60
61 ALSRQNLPQL EGSSIESASK GGYVLQDVAN PDIILVATGS EVSLSVEAAK TLAAKNIKAR 120
121 VVSLPDFFTF DKQPLEYRLS VLPDNVPIMS VEVLATTCWG KYAHQSFGID RFGASGKAPE 180
181 VFKFFGFTPE GVAERAQKTI AFYKGDKLIS PLKKAF
|
| Detection Method: | |
| Confidence: | 11000.0 |
| Match: | 1gpuA_ |
| Description: | Transketolase (TK), Pyr module; Transketolase (TK), PP module; Transketolase (TK), C-domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [367-464] |
1 11 21 31 41 51
| | | | | |
1 EDVYNQLPEL IGGSADLTPS NLTRWKEALD FQPPSSGSGN YSGRYIRYGI REHAMGAIMN 60
61 GISAFGANYK PYGGTFLNFV SYAAGAVRLS ALSGHPVI
|
| Detection Method: | |
| Confidence: | 11000.0 |
| Match: | 1gpuA_ |
| Description: | Transketolase (TK), Pyr module; Transketolase (TK), PP module; Transketolase (TK), C-domain |
| Matching Structure (courtesy of the PDB): |
|
