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View Structure Prediction Details

Protein: USV1
Organism: Saccharomyces cerevisiae
Length: 391 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for USV1.

Description E-value Query
Range
Subject
Range
ZNF347 - zinc finger protein 347
gi|208968133 - gi|208968133|dbj|BAG73905.1| zinc finger protein 347 [synthetic construct]
0.0 [1..391] [276..725]
gi|15929737, gi|... - gi|21703954|ref|NP_663458.1| zinc finger protein 160 [Mus musculus], gi|15929737|gb|AAH15291.1| Zinc...
0.0 [1..391] [189..610]

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Predicted Domain #1
Region A:
Residues: [1-115]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENTTNRNTA GVLTSSNGNF ATNSVAASTP KRSKSARRKT FKCTGYDGCT MSFTRAEHLA  60
   61 RHIRKHTGEK PFQCPACLKF FSRVDNLKQH RESVHAHKNH HSTSSHQRKP SSSSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 90.85005
Match: 1a1iA_
Description: ZIF268
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.70988788192472 bayes_pls_golite062009
nucleic acid binding 4.58713908116892 bayes_pls_golite062009
DNA binding 4.56219307357342 bayes_pls_golite062009
transcription activator activity 3.52873291636993 bayes_pls_golite062009
transcription factor activity 3.50954949535763 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.22082323675675 bayes_pls_golite062009
binding 3.10743787485868 bayes_pls_golite062009
sequence-specific DNA binding 2.53101891154822 bayes_pls_golite062009
chromatin binding 2.18464662431232 bayes_pls_golite062009
protein binding 2.05530362750351 bayes_pls_golite062009
transcription repressor activity 1.64349785387632 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.63161912031789 bayes_pls_golite062009
transcription factor binding 1.39608963544799 bayes_pls_golite062009
structure-specific DNA binding 0.790771220986801 bayes_pls_golite062009
transcription cofactor activity 0.77874411480713 bayes_pls_golite062009
double-stranded DNA binding 0.53991278722671 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009
transcription corepressor activity 0.10558148421807 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [116-171]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSSSASSSS SASSSTSYSD PYRKTNINSG NMPMMAENEK APQIIHSSPE FITSTR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [172-247]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIPPISPRSI YNTQRQQQHQ QQQHQQAPYY FPSHPITDSY YQYPLPSNNN TINYLPSVDV  60
   61 QYPLNVSPSS TSHPAS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.403 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.346 N/A N/A a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.346 N/A N/A a.135.1 Tetraspanin
View Download 0.299 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.295 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.237 N/A N/A d.205.1 GTP cyclohydrolase I feedback regulatory protein, GFRP
View Download 0.226 N/A N/A a.60.11 Hypothetical protein YjbJ
View Download 0.205 N/A N/A a.3.1 Cytochrome c

Predicted Domain #4
Region A:
Residues: [248-308]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVIISSFPPR SMPSTSFKYK DSADFQARTT MNKYNIRPSN INVNTSNINN HLDSFSPPFS  60
   61 P

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.550 N/A N/A d.9.2 Description not found.
View Download 0.449 N/A N/A d.95.1 Glucose permease domain IIB
View Download 0.415 N/A N/A d.9.1 Interleukin 8-like chemokines
View Download 0.392 N/A N/A g.41.3 Zinc beta-ribbon
View Download 0.370 N/A N/A d.9.1 Interleukin 8-like chemokines
View Download 0.339 N/A N/A b.40.4 Nucleic acid-binding proteins
View Download 0.330 N/A N/A d.9.1 Interleukin 8-like chemokines
View Download 0.264 N/A N/A d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.262 N/A N/A b.71.1 Glycosyl hydrolase domain
View Download 0.254 N/A N/A b.71.1 Glycosyl hydrolase domain
View Download 0.242 N/A N/A d.9.2 Description not found.
View Download 0.241 N/A N/A g.41.3 Zinc beta-ribbon
View Download 0.237 N/A N/A b.35.2 SacY-like RNA-binding domain
View Download 0.235 N/A N/A g.18.1 Complement control module/SCR domain
View Download 0.220 N/A N/A b.34.5 Translation proteins SH3-like domain
View Download 0.215 N/A N/A d.95.2 Homing endonucleases
View Download 0.201 N/A N/A d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14

Predicted Domain #5
Region A:
Residues: [309-391]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STTVAEAKPI ILPQYQQAFS QPPNGNKNNN MSSSKNGGKG GENFKNTDDR NDNNNKKRSE  60
   61 TLSESDISVN TNKKRLSVDY ILT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 86.144602
Match: 2adr__
Description: ADR1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle