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View Structure Prediction Details

Protein: ECM23
Organism: Saccharomyces cerevisiae
Length: 187 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ECM23.

Description E-value Query
Range
Subject
Range
ECM23_YEAST - Protein ECM23 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ECM23 PE=2 SV=1
ECM23 - Non-essential protein of unconfirmed function; affects pre-rRNA processing, may act as a negative re...
7.0E-30 [1..187] [1..187]
gi|7381420 - gi|7381420|gb|AAF61481.1|AF184154_1 zinc finger DNA binding protein pannier [Ceratitis capitata]
1.0E-25 [14..185] [42..217]
gi|603164 - gi|603164|gb|AAA67886.1| BmGATA beta isoform 1
1.0E-24 [73..186] [68..180]
pnr-PA - The gene pannier is referred to in FlyBase by the symbol Dmel\pnr (CG3978, FBgn0003117). It is a pro...
2.0E-24 [11..185] [95..278]
gi|33416800 - gi|33416800|gb|AAH55963.1| Gata-5b protein [Xenopus laevis]
5.0E-24 [9..182] [51..233]
gi|8778844 - gi|8778844|gb|AAF79843.1|AC026875_23 T6D22.9 [Arabidopsis thaliana]
7.0E-24 [3..174] [168..342]

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Predicted Domain #1
Region A:
Residues: [1-116]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLYNKEQGTS GASSSGRRTK FHFDRFVQMV LFIAANPNYC CSVASIPKSG VTPDLKRADI  60
   61 LEQKIKSLNS ALSPKLKEES RLGGPLHNPS ILPAPSFSSL PISSNGKKSL AGYRPK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [117-187]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRKKQTILPN GQPKECATCG DTWTSQWRSG PNGNVELCSR CGIAYRKKME KKIRSQQSSD  60
   61 DGTKNFIFKN K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 4gatA_
Description: Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.86425331852532 bayes_pls_golite062009
protein binding 1.03915863262476 bayes_pls_golite062009
transcription regulator activity 0.444271462960894 bayes_pls_golite062009
DNA binding 0.286544225540259 bayes_pls_golite062009
nucleic acid binding 0.153249001846128 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle