YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: ECM23
Organism: Saccharomyces cerevisiae
Length: 187 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ECM23.

Description E-value Query
Range
Subject
Range
ECM23_YEAST - Protein ECM23 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ECM23 PE=2 SV=1
ECM23 - Non-essential protein of unconfirmed function; affects pre-rRNA processing, may act as a negative re...
7.0E-30 [1..187] [1..187]
gi|7381420 - gi|7381420|gb|AAF61481.1|AF184154_1 zinc finger DNA binding protein pannier [Ceratitis capitata]
1.0E-25 [14..185] [42..217]
gi|603164 - gi|603164|gb|AAA67886.1| BmGATA beta isoform 1
1.0E-24 [73..186] [68..180]
pnr-PA - The gene pannier is referred to in FlyBase by the symbol Dmel\pnr (CG3978, FBgn0003117). It is a pro...
2.0E-24 [11..185] [95..278]
gi|33416800 - gi|33416800|gb|AAH55963.1| Gata-5b protein [Xenopus laevis]
5.0E-24 [9..182] [51..233]
gi|8778844 - gi|8778844|gb|AAF79843.1|AC026875_23 T6D22.9 [Arabidopsis thaliana]
7.0E-24 [3..174] [168..342]

Back

Predicted Domain #1
Region A:
Residues: [1-116]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLYNKEQGTS GASSSGRRTK FHFDRFVQMV LFIAANPNYC CSVASIPKSG VTPDLKRADI  60
   61 LEQKIKSLNS ALSPKLKEES RLGGPLHNPS ILPAPSFSSL PISSNGKKSL AGYRPK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.479 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.450 a.26.1 4-helical cytokines
View Download 0.350 a.7.7 BAG domain
View Download 0.348 a.68.1 Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
View Download 0.479 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.450 a.26.1 4-helical cytokines
View Download 0.428 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.350 a.7.7 BAG domain
View Download 0.348 a.68.1 Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
View Download 0.345 a.142.1 PTS-regulatory domain, PRD
View Download 0.332 d.109.2 C-terminal, gelsolin-like domain of Sec23/24
View Download 0.331 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.321 a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.320 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.315 d.201.1 SRP19
View Download 0.309 a.47.2 t-snare proteins
View Download 0.309 a.26.1 4-helical cytokines
View Download 0.291 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.291 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.291 a.90.1 Transcription factor STAT-4 N-domain
View Download 0.288 f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.268 a.96.1 DNA-glycosylase
View Download 0.254 a.7.6 Ribosomal protein S20
View Download 0.252 c.52.1 Restriction endonuclease-like
View Download 0.250 f.1.5 Exotoxin A, middle domain
View Download 0.249 a.60.13 Putative methyltransferase TM0872, insert domain
View Download 0.229 a.74.1 Cyclin-like
View Download 0.229 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.221 a.46.1 Methionine synthase domain
View Download 0.217 a.135.1 Tetraspanin
View Download 0.215 d.110.2 GAF domain-like
View Download 0.214 a.74.1 Cyclin-like
View Download 0.208 a.39.1 EF-hand
View Download 0.202 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like

Predicted Domain #2
Region A:
Residues: [117-187]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRKKQTILPN GQPKECATCG DTWTSQWRSG PNGNVELCSR CGIAYRKKME KKIRSQQSSD  60
   61 DGTKNFIFKN K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 4gatA_
Description: Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.86425331852532 bayes_pls_golite062009
protein binding 1.03915863262476 bayes_pls_golite062009
transcription regulator activity 0.444271462960894 bayes_pls_golite062009
DNA binding 0.286544225540259 bayes_pls_golite062009
nucleic acid binding 0.153249001846128 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle