| Protein: | MIP1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1280 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MIP1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [27..1280] | [1..1254] |
|
|
0.0 | [53..1055] | [39..1086] |
|
|
0.0 | [53..1060] | [8..1001] |
|
|
0.0 | [53..1003] | [29..973] |
|
|
0.0 | [53..1003] | [29..973] |
|
|
0.0 | [68..1006] | [54..1133] |
|
Region A: Residues: [1-241] |
1 11 21 31 41 51
| | | | | |
1 MDYERTVLKK RSRWGLYVVV EQRGTSMTKL MVRSECMLRM VRRRPLRVQF CARWFSTKKN 60
61 TAEAPRINPV GIQYLGESLQ RQVFGSCGGK DEVEQSDKLM ELSKKSLKDH GLWGKKTLIT 120
121 DPISFPLPPL QGRSLDEHFQ KIGRFNSEPY KSFCEDKFTE MVARPAEWLR KPGWVKYVPG 180
181 MAPVEVAYPD EELVVFDVET LYNVSDYPTL ATALSSTAWY LWCSPFICGG DDPAALIPLN 240
241 T
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [242-393] |
1 11 21 31 41 51
| | | | | |
1 LNKEQVIIGH NVAYDRARVL EEYNFRDSKA FFLDTQSLHI ASFGLCSRQR PMFMKNNKKK 60
61 EAEVESEVHP EISIEDYDDP WLNVSALNSL KDVAKFHCKI DLDKTDRDFF ASTDKSTIIE 120
121 NFQKLVNYCA TDVTATSQVF DEIFPVFLKK CP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [394-541] |
1 11 21 31 41 51
| | | | | |
1 HPVSFAGLKS LSKCILPTKL NDWNDYLNSS ESLYQQSKVQ IESKIVQIIK DIVLLKDKPD 60
61 FYLKDPWLSQ LDWTTKPLRL TKKGVPAKCQ KLPGFPEWYR QLFPSKDTVE PKITIKSRII 120
121 PILFKLSWEN SPVIWSKESG WCFNVPHE
|
|
Region B: Residues: [707-722] |
1 11 21 31 41 51
| | | | | |
1 VKAPPGYCFV GADVDS
|
|
Region C: Residues: [887-1011] |
1 11 21 31 41 51
| | | | | |
1 SGVDYLHLLC CSMEYIIKKY NLEARLCISI HDEIRFLVSE KDKYRAAMAL QISNIWTRAM 60
61 FCQQMGINEL PQNCAFFSQV DIDSVIRKEV NMDCITPSNK TAIPHGEALD INQLLDKSNS 120
121 KLGKP
|
| Detection Method: | |
| Confidence: | 152.0 |
| Match: | 1d8yA_ |
| Description: | Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| DNA polymerase activity | 7.87431862983329 | bayes_pls_golite062009 |
| DNA-directed DNA polymerase activity | 7.78411937387917 | bayes_pls_golite062009 |
| nucleotidyltransferase activity | 5.3880945520411 | bayes_pls_golite062009 |
| exonuclease activity | 2.86892175148145 | bayes_pls_golite062009 |
| nuclease activity | 2.84202779131927 | bayes_pls_golite062009 |
| exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 1.94077739152313 | bayes_pls_golite062009 |
| deoxyribonuclease activity | 1.87431870698721 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.87430802282815 | bayes_pls_golite062009 |
| ribonuclease activity | 1.82848379742483 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 1.75713164321634 | bayes_pls_golite062009 |
| transferase activity | 1.47288345517763 | bayes_pls_golite062009 |
| catalytic activity | 1.25233849524628 | bayes_pls_golite062009 |
| endonuclease activity | 0.935348031740788 | bayes_pls_golite062009 |
| exodeoxyribonuclease activity, producing 5'-phosphomonoesters | 0.782108781904855 | bayes_pls_golite062009 |
| binding | 0.777766550398053 | bayes_pls_golite062009 |
| exodeoxyribonuclease activity | 0.77421125364834 | bayes_pls_golite062009 |
| 3'-5' exonuclease activity | 0.72566997912926 | bayes_pls_golite062009 |
| nucleic acid binding | 0.539345587157456 | bayes_pls_golite062009 |
| endodeoxyribonuclease activity | 0.48776342704945 | bayes_pls_golite062009 |
| transcription regulator activity | 0.265266702292727 | bayes_pls_golite062009 |
| exoribonuclease activity | 0.14466215642144 | bayes_pls_golite062009 |
| DNA binding | 0.119847375774469 | bayes_pls_golite062009 |
| exoribonuclease activity, producing 5'-phosphomonoesters | 0.0662718964590603 | bayes_pls_golite062009 |
| protein binding | 0.058257360610363 | bayes_pls_golite062009 |
|
Region A: Residues: [542-571] |
1 11 21 31 41 51
| | | | | |
1 QVETYKAKNY VLADSVSQEE EEIRTHNLGL
|
|
Region B: Residues: [644-706] |
1 11 21 31 41 51
| | | | | |
1 KFPNEFQSLS AKSSLNNEKT NDLAIIIPKI VPMGTITRRA VENAWLTASN AKANRIGSEL 60
61 KTQ
|
|
Region C: Residues: [723-886] |
1 11 21 31 41 51
| | | | | |
1 EELWIASLVG DSIFNVHGGT AIGWMCLEGT KNEGTDLHTK TAQILGCSRN EAKIFNYGRI 60
61 YGAGAKFASQ LLKRFNPSLT DEETKKIANK LYENTKGKTK RSKLFKKFWY GGSESILFNK 120
121 LESIAEQETP KTPVLGCGIT YSLMKKNLRA NSFLPSRINW AIQS
|
| Detection Method: | |
| Confidence: | 152.0 |
| Match: | 1d8yA_ |
| Description: | Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment) |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [572-643] |
1 11 21 31 41 51
| | | | | |
1 QCTGVLFKVP HPNGPTFNCT NLLTKSYNHF FEKGVLKSES ELAHQALQIN SSGSYWMSAR 60
61 ERIQSQFVVP SC
|
| Detection Method: | |
| Confidence: | 152.0 |
| Match: | 1d8yA_ |
| Description: | Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment) |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1012-1280] |
1 11 21 31 41 51
| | | | | |
1 NLDIDSKVSQ YAYNYREPVF EEYNKSYTPE FLKYFLAMQV QSDKRDVNRL EDEYLRECTS 60
61 KEYARDGNTA EYSLLDYIKD VEKGKRTKVR IMGSNFLDGT KNAKADQRIR LPVNMPDYPT 120
121 LHKIANDSAI PEKQLLENRR KKENRIDDEN KKKLTRKKNT TPMERKYKRV YGGRKAFEAF 180
181 YECANKPLDY TLETEKQFFN IPIDGVIDDV LNDKSNYKKK PSQARTASSS PIRKTAKAVH 240
241 SKKLPARKSS TTNRNLVELE RDITISREY
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
