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View Structure Prediction Details

Protein: YRM1
Organism: Saccharomyces cerevisiae
Length: 786 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YRM1.

Description E-value Query
Range
Subject
Range
YRM1_YEAST - Zinc finger transcription factor YRM1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YR...
YRM1 - Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; par...
0.0 [1..786] [1..786]
YGDC_SCHPO - Uncharacterized transcriptional regulatory protein C1773.12 OS=Schizosaccharomyces pombe (strain 972...
SPBC1773.12 - transcription factor
1.0E-80 [25..635] [5..553]
gi|14279690 - gi|14279690|gb|AAK58691.1|AF272849_1 nitrogen regulatory protein OTam [Aspergillus oryzae]
5.0E-69 [5..618] [35..630]
gi|2262187 - gi|2262187|gb|AAB63563.1| FacB [Aspergillus niger]
1.0E-68 [21..583] [14..564]
ACU15_NEUCR - Transcriptional activator protein acu-15 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS ...
ACU15_NEUCR, AC1... - Transcriptional activator protein acu-15 OS=Neurospora crassa GN=acu-15 PE=1 SV=2, (P87000) Transcri...
2.0E-68 [21..565] [14..549]

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Predicted Domain #1
Region A:
Residues: [1-100]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKRGSLQDR ASPSEETVKK AQKRRKPIKS CAFCRKRKLR CDQQKPMCST CKTRGRSGCL  60
   61 YTEKFTHKIE TKELFGSTPN IELLKRIEDL EKRLDDKELT 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 70.228787
Match: 1hwtD_
Description: Hap1 (Cyp1); HAP1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.56444258780502 bayes_pls_golite062009
DNA binding 4.26146437716972 bayes_pls_golite062009
nucleic acid binding 4.17369933547911 bayes_pls_golite062009
transcription factor activity 3.049435548132 bayes_pls_golite062009
sequence-specific DNA binding 2.98081393153291 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.93914501897006 bayes_pls_golite062009
binding 2.91929847152301 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 2.44382866473054 bayes_pls_golite062009
transcription activator activity 2.24483536326713 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [101-556]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKDVALSTSP FRNPYANFYY LQCKGSGRRI VYGPTSLRTH LSNDDNRFVN TYNQLWSKVK  60
   61 IERNRWKARH KWTMKPETQL LEGPPLEKTG SDILQQVCNV LPSFEQSSKI ITDFFNTELE 120
  121 TNEVSEVLDK TKIINDFTSS FLPSDELLPN GERRIEKLLP STKKNYYKIG VILMILCIRH 180
  181 FYKNTPEEIE KFLIMLTGLS TAKVYFIERA QFLLLKYYHR ELIWACGDDS HMISLVDLLC 240
  241 STAIMLGLHL NIREIYKNQE NIVGSMESLE NLWVWIILSD FNVSLNIGRC LAINSSYFQV 300
  301 DECENGERLP KNTNNYSSTV FFDQSNSCMG KLKRFLRLAR PMLDQIYDRS AFPDLAENCK 360
  361 KLRNFVETEF HPISYYTDSE LISKVPLCEI KVLAQVLNLL LTFYSLRYLI YKEKSVVLEN 420
  421 NILQTILVSF SLVINTTILC FNLDEKHFPE FFDHNC

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [557-786]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VHLPPFMALS LVYTNFLFPR ASTGFCAFLY HKLTLFEKGY YLSSNIKDQE VTDWDLSTLN  60
   61 IPLDKAMNLL TAFKIHSDIF AKWSNDNNKQ LRIIMARSYT FVINIALESI YRAVLEKVIK 120
  121 YRTEVENTWL QQLQDELNGS YSLTDNVNTP IDPSLSDLGV TSASPLAGNS PGLPPEEVRN 180
  181 NSENASHNNE TGPIETELAQ TISNEFWTAY NLGWEELMSQ PDYKYLFDTQ 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle