| Protein: | SKI7 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 747 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SKI7.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..747] | [1..747] |
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0.0 | [261..746] | [1..440] |
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0.0 | [261..746] | [1..440] |
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0.0 | [261..746] | [1..440] |
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0.0 | [261..746] | [1..440] |
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0.0 | [261..746] | [1..440] |
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0.0 | [261..746] | [1..438] |
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Region A: Residues: [1-70] |
1 11 21 31 41 51
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1 MSLLEQLARK RIEKSKGLLS ADQSHSTSKS ASLLERLHKN RETKDNNAET KRKDLKTLLA 60
61 KDKVKRSDFT
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| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.684 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.698 | a.64.1 | Saposin |
| View | Download | 0.719 | a.60.2 | RuvA domain 2-like |
| View | Download | 0.602 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.532 | a.159.1 | Protein serine/threonine phosphatase 2C, C-terminal domain |
| View | Download | 0.523 | a.2.3 | Chaperone J-domain |
| View | Download | 0.483 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.464 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.460 | a.156.1 | S13-like H2TH domain |
| View | Download | 0.382 | a.24.15 | FAD-dependent thiol oxidase |
| View | Download | 0.367 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.363 | d.58.17 | Metal-binding domain |
| View | Download | 0.349 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.348 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.339 | d.58.13 | Anticodon-binding domain of PheRS |
| View | Download | 0.330 | a.3.1 | Cytochrome c |
| View | Download | 0.328 | a.142.1 | PTS-regulatory domain, PRD |
| View | Download | 0.319 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.318 | a.144.1 | PABC (PABP) domain |
| View | Download | 0.318 | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.315 | a.5.6 | Hypothetical protein MTH1615 |
| View | Download | 0.309 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.304 | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.295 | a.39.1 | EF-hand |
| View | Download | 0.293 | a.4.1 | Homeodomain-like |
| View | Download | 0.292 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.291 | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.285 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.280 | a.64.1 | Saposin |
| View | Download | 0.274 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.273 | d.64.1 | eIF1-like |
| View | Download | 0.271 | a.164.1 | C-terminal domain of DFF45/ICAD (DFF-C domain) |
| View | Download | 0.270 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.265 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.257 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.247 | a.4.1 | Homeodomain-like |
| View | Download | 0.244 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.241 | a.77.1 | DEATH domain |
| View | Download | 0.240 | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.239 | a.1.1 | Globin-like |
| View | Download | 0.232 | a.159.2 | FF domain |
| View | Download | 0.232 | a.29.4 | RecG, N-terminal domain |
| View | Download | 0.226 | a.4.1 | Homeodomain-like |
| View | Download | 0.225 | a.28.1 | ACP-like |
| View | Download | 0.220 | a.17.1 | p8-MTCP1 |
| View | Download | 0.219 | a.39.1 | EF-hand |
| View | Download | 0.219 | a.74.1 | Cyclin-like |
| View | Download | 0.219 | d.50.2 | Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain |
| View | Download | 0.216 | a.112.1 | Description not found. |
| View | Download | 0.212 | a.163.1 | Crustacean CHH/MIH/GIH neurohormone |
| View | Download | 0.212 | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.208 | d.58.1 | 4Fe-4S ferredoxins |
| View | Download | 0.203 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
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Region A: Residues: [71-260] |
1 11 21 31 41 51
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1 PNQHSVSLSL KLSALKKSNS DLEKQGKSVT LDSKENELPT KRKSPDDKLN LEESWKAIKE 60
61 MNHYCFLKND PCINQTDDFA FTNFIIKDKK NSLSTSIPLS SQNSSFLSLK KHNNELLGIF 120
121 VPCNLPKTTR KVAIENFNRP SPDDIIQSAQ LNAFNEKLEN LNIKSVPKAE KKEPINLQTP 180
181 PTESIDIHSF
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| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
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Region A: Residues: [261-293] |
1 11 21 31 41 51
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1 IATHPLNLTC LFLGDTNAGK STLLGHLLYD LNE
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Region B: Residues: [337-516] |
1 11 21 31 41 51
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1 KVIQVENDLL PPSSTLTLID TPGSIKYFNK ETLNSILTFD PEVYVLVIDC NYDSWEKSLD 60
61 GPNNQIYEIL KVISYLNKNS ACKKHLIILL NKADLISWDK HRLEMIQSEL NYVLKENFQW 120
121 TDAEFQFIPC SGLLGSNLNK TENITKSKYK SEFDSINYVP EWYEGPTFFS QLYLLVEHNM 180
181
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| Detection Method: | |
| Confidence: | 1110.0 |
| Match: | 1f60A_ |
| Description: | Elongation factor eEF-1alpha, domain 2; Elongation factor eEF-1alpha, C-terminal domain; Elongation factor eEF-1alpha, N-terminal (G) domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ribonuclease activity | 4.3040603813219 | bayes_pls_golite062009 |
| hydrolase activity | 2.55157966585974 | bayes_pls_golite062009 |
| exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 1.44266227866728 | bayes_pls_golite062009 |
| binding | 1.41264401383678 | bayes_pls_golite062009 |
| exonuclease activity | 1.15670533472751 | bayes_pls_golite062009 |
| nuclease activity | 1.06224744208356 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| structural constituent of ribosome | 0.860102064846772 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 0.759324158861044 | bayes_pls_golite062009 |
| RNA binding | 0.707596564331465 | bayes_pls_golite062009 |
| nucleic acid binding | 0.625617128641089 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.569910969126728 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.568840867400671 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.568779924702229 | bayes_pls_golite062009 |
| nucleotide binding | 0.564275755355315 | bayes_pls_golite062009 |
| 0.40076293158639 | bayes_pls_golite062009 | |
| translation regulator activity | 0.29096092258568 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.274994961137851 | bayes_pls_golite062009 |
| translation termination factor activity | 0.269303802954244 | bayes_pls_golite062009 |
| translation release factor activity | 0.252222008028593 | bayes_pls_golite062009 |
| ATP binding | 0.1860481660648 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 0.152859582615242 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.147579541298736 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 0.138615225841109 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.133017653323467 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.113504049290503 | bayes_pls_golite062009 |
| structural molecule activity | 0.11239762372728 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.111293884322157 | bayes_pls_golite062009 |
| DNA binding | 0.0064778111446141 | bayes_pls_golite062009 |
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Region A: Residues: [294-336] |
1 11 21 31 41 51
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1 ISMSSMRELQ KKSSNLDPSS SNSFKVILDN TKTERENGFS MFK
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Region B: Residues: [517-638] |
1 11 21 31 41 51
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1 NKIETTLEEP FVGTILQSSV LQPIAEINYV SLKVLINSGY IQSGQTIEIH TQYEDFHYYG 60
61 IVSRMKNSKQ ILETNTKNNI SVGLNPDILE VLVKIHNTED FTKKQFHIRK GDIIIHSRKT 120
121 NT
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| Detection Method: | |
| Confidence: | 1110.0 |
| Match: | 1f60A_ |
| Description: | Elongation factor eEF-1alpha, domain 2; Elongation factor eEF-1alpha, C-terminal domain; Elongation factor eEF-1alpha, N-terminal (G) domain |
| Matching Structure (courtesy of the PDB): |
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Region A: Residues: [639-747] |
1 11 21 31 41 51
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1 LSPNLPNTLK LLALRLIKLS IQTHALSDPV DLGSELLLYH NLTHNAVKLV KILGTNDISI 60
61 NPNQSLIVEV EIIEPDFALN VIDSKYITNN IVLTSIDHKV IAVGRIACQ
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| Detection Method: | |
| Confidence: | 1110.0 |
| Match: | 1f60A_ |
| Description: | Elongation factor eEF-1alpha, domain 2; Elongation factor eEF-1alpha, C-terminal domain; Elongation factor eEF-1alpha, N-terminal (G) domain |
| Matching Structure (courtesy of the PDB): |
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