| Protein: | DNL4 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 944 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DNL4.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..944] | [1..944] |
|
|
0.0 | [7..936] | [2..906] |
|
|
0.0 | [1..939] | [1..910] |
|
|
0.0 | [73..938] | [1..840] |
|
|
0.0 | [9..938] | [11..923] |
|
|
0.0 | [30..936] | [6..904] |
|
|
0.0 | [9..862] | [11..845] |
|
|
0.0 | [10..833] | [11..806] |
|
|
0.0 | [13..873] | [4..859] |
|
Region A: Residues: [1-242] |
1 11 21 31 41 51
| | | | | |
1 MISALDSIPE PQNFAPSPDF KWLCEELFVK IHEVQINGTA GTGKSRSFKY YEIISNFVEM 60
61 WRKTVGNNIY PALVLALPYR DRRIYNIKDY VLIRTICSYL KLPKNSATEQ RLKDWKQRVG 120
121 KGGNLSSLLV EEIAKRRAEP SSKAITIDNV NHYLDSLSGD RFASGRGFKS LVKSKPFLHC 180
181 VENMSFVELK YFFDIVLKNR VIGGQEHKLL NCWHPDAQDY LSVISDLKVV TSKLYDPKVR 240
241 LK
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| DNA ligase activity | 10.0279903057926 | bayes_pls_golite062009 |
| ligase activity, forming phosphoric ester bonds | 9.92846900587219 | bayes_pls_golite062009 |
| DNA ligase (ATP) activity | 8.51283882444113 | bayes_pls_golite062009 |
| DNA ligase (NAD+) activity | 3.17397926295565 | bayes_pls_golite062009 |
| ligase activity | 2.36807839237461 | bayes_pls_golite062009 |
| catalytic activity | 2.15370807854636 | bayes_pls_golite062009 |
| binding | 1.82998145778732 | bayes_pls_golite062009 |
| protein binding | 1.38006517521813 | bayes_pls_golite062009 |
| nucleic acid binding | 1.06318697852063 | bayes_pls_golite062009 |
| DNA binding | 0.920391596538289 | bayes_pls_golite062009 |
|
Region A: Residues: [243-309] |
1 11 21 31 41 51
| | | | | |
1 DDDLSIKVGF AFAPQLAKKV NLSYEKICRT LHDDFLVEEK MDGERIQVHY MNYGESIKFF 60
61 SRRGIDY
|
| Detection Method: | |
| Confidence: | 8.04 |
| Match: | 1fviA |
| Description: | ATP-dependent DNA ligase; ATP-dependent DNA ligase, N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [310-421] |
1 11 21 31 41 51
| | | | | |
1 TYLYGASLSS GTISQHLRFT DSVKECVLDG EMVTFDAKRR VILPFGLVKG SAKEALSFNS 60
61 INNVDFHPLY MVFDLLYLNG TSLTPLPLHQ RKQYLNSILS PLKNIVEIVR SS
|
| Detection Method: | |
| Confidence: | 26.30103 |
| Match: | 1fviA_ |
| Description: | ATP-dependent DNA ligase; ATP-dependent DNA ligase, N-terminal domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [422-468] |
1 11 21 31 41 51
| | | | | |
1 RCYGVESIKK SLEVAISLGS EGVVLKYYNS SYNVASRNNN WIKVKPE
|
| Detection Method: | |
| Confidence: | 26.30103 |
| Match: | 1fviA_ |
| Description: | ATP-dependent DNA ligase; ATP-dependent DNA ligase, N-terminal domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [469-579] |
1 11 21 31 41 51
| | | | | |
1 YLEEFGENLD LIVIGRDSGK KDSFMLGLLV LDEEEYKKHQ GDSSEIVDHS SQEKHIQNSR 60
61 RRVKKILSFC SIANGISQEE FKEIDRKTRG HWKRTSEVAP PASILEFGSK I
|
| Detection Method: | |
| Confidence: | 26.30103 |
| Match: | 1fviA_ |
| Description: | ATP-dependent DNA ligase; ATP-dependent DNA ligase, N-terminal domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [580-733] |
1 11 21 31 41 51
| | | | | |
1 PAEWIDPSES IVLEIKSRSL DNTETNMQKY ATNCTLYGGY CKRIRYDKEW TDCYTLNDLY 60
61 ESRTVKSNPS YQAERSQLGL IRKKRKRVLI SDSFHQNRKQ LPISNIFAGL LFYVLSDYVT 120
121 EDTGIRITRA ELEKTIVEHG GKLIYNVILK RHSI
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [734-816] |
1 11 21 31 41 51
| | | | | |
1 GDVRLISCKT TTECKALIDR GYDILHPNWV LDCIAYKRLI LIEPNYCFNV SQKMRAVAEK 60
61 RVDCLGDSFE NDISETKLSS LYK
|
| Detection Method: | |
| Confidence: | 5.39794 |
| Match: | 1ik9C_ |
| Description: | CRYSTAL STRUCTURE OF A XRCC4-DNA LIGASE IV COMPLEX |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [817-944] |
1 11 21 31 41 51
| | | | | |
1 SQLSLPPMGE LEIDSEVRRF PLFLFSNRIA YVPRRKISTE DDIIEMKIKL FGGKITDQQS 60
61 LCNLIIIPYT DPILRKDCMN EVHEKIKEQI KASDTIPKIA RVVAPEWVDH SINENCQVPE 120
121 EDFPVVNY
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.318 | a.1.1 | Globin-like |
| View | Download | 0.428 | a.118.1 | ARM repeat |
| View | Download | 0.322 | a.7.1 | Spectrin repeat |
| View | Download | 0.309 | a.29.2 | Bromodomain |
| View | Download | 0.341 | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.265 | a.25.1 | Ferritin-like |
| View | Download | 0.258 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.247 | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.233 | a.79.1 | Antitermination factor NusB |
| View | Download | 0.233 | a.29.2 | Bromodomain |
| View | Download | 0.230 | a.25.1 | Ferritin-like |
| View | Download | 0.226 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.225 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
