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View Structure Prediction Details

Protein: UTP23
Organism: Saccharomyces cerevisiae
Length: 254 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UTP23.

Description E-value Query
Range
Subject
Range
gi|151945633 - gi|151945633|gb|EDN63874.1| SSU processome protein [Saccharomyces cerevisiae YJM789]
UTP23_YEAST - rRNA-processing protein UTP23 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UTP23 PE=1...
UTP23 - Essential nucleolar protein that is a component of the SSU (small subunit) processome involved in 40...
gi|207341292 - gi|207341292|gb|EDZ69389.1| YOR004Wp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190407345 - gi|190407345|gb|EDV10612.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
2.0E-75 [1..254] [1..254]
UTP23 - UTP23, small subunit (SSU) processome component, homolog (yeast)
3.0E-68 [1..217] [1..217]
UTP23_MOUSE - rRNA-processing protein UTP23 homolog OS=Mus musculus GN=Utp23 PE=2 SV=1
3.0E-65 [1..217] [1..218]
CG17652-PA, FBpp... - This gene is referred to in FlyBase by the symbol Dmel\CG17652 (CG17652, FBgn0031361). It is a prote...
1.0E-58 [1..237] [1..232]
UTP23_SCHPO - rRNA-processing protein utp23 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=utp23 PE=3 S...
SPCC18.12c - rRNA processing protein
4.0E-58 [1..219] [1..238]
CE27743 - status:Confirmed UniProt:Q95QS4 protein_id:AAK67218.1
2.0E-53 [1..227] [1..215]
gi|20197374, gi|... - gi|20197374|gb|AAC62883.2| expressed protein [Arabidopsis thaliana], gi|18407014|ref|NP_566068.1| un...
8.0E-49 [14..159] [51..193]

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Predicted Domain #1
Region A:
Residues: [1-198]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRQKRAKSYR KQLLVYSHTF KFREPYQVLV DNQLVLECNN SNFNLPSGLK RTLQADVKVM  60
   61 ITQCCIQALY ETRNDGAINL AKQFERRRCN HSFKDPKSPA ECIESVVNIS GANKHRYVVA 120
  121 SQDIDLRRKL RTVPGVPLIH LTRSVMVMEP LSTASAKASK ITEEQKLYKG LNDPNIEKLQ 180
  181 ESGDGSGKES ITKKRKLG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
nuclease activity 2.9643999717473 bayes_pls_golite062009
exonuclease activity 2.73966722455965 bayes_pls_golite062009
endodeoxyribonuclease activity 2.32240591300465 bayes_pls_golite062009
deoxyribonuclease activity 2.20319910135606 bayes_pls_golite062009
DNA binding 2.08813762501061 bayes_pls_golite062009
nucleic acid binding 1.94354032094901 bayes_pls_golite062009
flap endonuclease activity 1.93047867791632 bayes_pls_golite062009
binding 1.92045449238153 bayes_pls_golite062009
endonuclease activity 1.76157945742159 bayes_pls_golite062009
hydrolase activity 1.70203323769024 bayes_pls_golite062009
5'-3' exonuclease activity 1.66809858159343 bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.5104333947608 bayes_pls_golite062009
catalytic activity 1.37534898662234 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.24621366977274 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.0761952249864 bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters 0.756864776606945 bayes_pls_golite062009
exodeoxyribonuclease activity 0.74826759322705 bayes_pls_golite062009
protein binding 0.696235153462548 bayes_pls_golite062009
3'-5' exonuclease activity 0.50487165366129 bayes_pls_golite062009
5'-3' exodeoxyribonuclease activity 0.34527101309477 bayes_pls_golite062009
double-stranded DNA specific exodeoxyribonuclease activity 0.123105804280941 bayes_pls_golite062009
single-stranded DNA specific exodeoxyribonuclease activity 0.120278857913627 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [199-254]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKAPNPLSVK KKKKVNSPSD EVKDKEDTSK EKKKRRRRKH KSNTNVPVSN GTTAAQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle