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View Structure Prediction Details

Protein: FKH2
Organism: Saccharomyces cerevisiae
Length: 862 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FKH2.

Description E-value Query
Range
Subject
Range
gi|1098481, gi|2... - gi|2253173|emb|CAA95941.1| FKH2 [Saccharomyces cerevisiae], gi|1098481|gb|AAA99643.1| Ynl2403p
408.0 [0..1] [440..1]
gi|49527461, gi|... - gi|50291435|ref|XP_448150.1| unnamed protein product [Candida glabrata], gi|49527461|emb|CAG61101.1|...
gi|49527461 - gi|49527461|emb|CAG61101.1| unnamed protein product [Candida glabrata]
228.0 [0..26] [655..5]
MUC1 - mucin 1, cell surface associated
218.0 [0..154] [833..356]
gi|49644425 - gi|49644425|emb|CAG97997.1| KLLA0F04631p [Kluyveromyces lactis]
gi|49644425, gi|... - gi|50310539|ref|XP_455289.1| unnamed protein product [Kluyveromyces lactis], gi|49644425|emb|CAG9799...
212.0 [0..7] [683..33]
TCNA_TRYCR - Sialidase OS=Trypanosoma cruzi GN=TCNA PE=2 SV=1
203.0 [0..295] [861..578]
gi|109083400 - gi|109083400|ref|XP_001086449.1| PREDICTED: similar to forkhead box A1 [Macaca mulatta]
201.0 [0..202] [660..218]
fhl1 - fork head transcription factor Fhl1
FHL1_SCHPO - Fork head transcription factor 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=fhl1 PE=3...
200.0 [0..46] [688..2]
gi|2352801 - gi|2352801|gb|AAB69278.1| fork head 1 [Molgula oculata]
192.0 [0..228] [746..2]

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Predicted Domain #1
Region A:
Residues: [1-214]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSNFNEMN ELNMTQTNYG STKYTAQHHQ GVINAIISSL TAPDQPTTVS LQYSNDKNMA  60
   61 TEIQAYAKLS GPNWTYYVKD LEVSIGRNTD PLNSALQENS DGVKNSYRVN IDLGPAKVVS 120
  121 RKHAIIKYNM NIGGWELHIL GRNGAKVNFQ RTHNGPNNPP IRLSSGTLLD IGGTQMMFIL 180
  181 PDSDPVVAPI CIEHLMPNLI NMFGLEGNNN PLLR

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 12.16
Match:
Description: No description for 1g3gA was found.

Predicted Domain #2
Region A:
Residues: [215-337]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DIIKQSNYAK QRQLTSNQQI KGFKLYGSGG NAPFGSGANL GPSEQGIFNN NNNSKNKNGY  60
   61 FTSINPNYTA STTTSNTINP QAASPQGPPN TIIAANFVDS YKSSNAYPQA LDFTSDLSHD 120
  121 ENR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [338-430]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVKPPHSYAT MITQAILSSP EGVISLADIY KYISSNYAYY RFAKSGWQNS IRHNLSLNKA  60
   61 FEKVPRRPNE PGKGMKWRIS ESYQQEFLNK WNT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 217.9897
Match: 1d5vA
Description: Adipocyte-transcription factor FREAC-11 (s12, fkh-14)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [431-862]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKVGKIRRGS SVARQLQLHM AKFNSLPMEM DYRLSLNMAQ PPKRQLQSHN VLEPSNNNII  60
   61 EGFVQHVPSK GNLPASQQSQ PPVSHQNQSQ QPPPQEQRQE IQFTFADTQN RNIALARPIK 120
  121 TPQLQAPNSN ANLNQNNMKE YKESLHPPAI SISQMNRQSP NNALVSFTNA CANSKIINNI 180
  181 SDSADKSTNN NGGTKMNLPA ISTSSLDENG NLEPTTTTSS GNSNSVPQTG TTTSSLAANS 240
  241 LRLSQPYDTL LRSPTKAFHI TAMEAYTPER GSANRARSPL HSNSNNTNNN GANNSNLQTS 300
  301 GMENKQTGLV LDSNVLKSME SNNDNRRLTP STSKSQNVKS SPGVWNLLQF SSTNNTPAAD 360
  361 SGGNKRGFSI NPDIKAKENE NATSEKDSDS NSNDLETKDI NSSPLKNQGG STANAKELIL 420
  421 DTDGAKISII NN

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 11.22
Match:
Description: No description for 1i3qA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle