YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: CLN1
Organism: Saccharomyces cerevisiae
Length: 546 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CLN1.

Description E-value Query
Range
Subject
Range
CLN1 - G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S p...
CG11_YEAST - G1/S-specific cyclin CLN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CLN1 PE=1 SV=2
0.0 [1..546] [1..546]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-95 [4..342] [127..424]
CCN1_ANTMA - G2/mitotic-specific cyclin-1 OS=Antirrhinum majus PE=2 SV=1
3.0E-94 [4..353] [163..463]
gi|7271222 - gi|7271222|emb|CAB81558.1| cyclin B1 [Nicotiana tabacum]
9.0E-94 [4..340] [127..422]
gi|9502284 - gi|9502284|gb|AAF88072.1| cyclin [Cicer arietinum]
5.0E-93 [4..353] [163..465]
gi|1835260 - gi|1835260|emb|CAA99990.1| mitotic cyclin [Sesbania rostrata]
3.0E-92 [4..332] [158..440]
CCNB1_SOYBN - G2/mitotic-specific cyclin S13-6 OS=Glycine max PE=2 SV=1
7.0E-92 [4..332] [163..446]

Back

Predicted Domain #1
Region A:
Residues: [1-48]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNHSEVKTGL IVTAKQTYYP IELSNAELLT HYETIQEYHE EISQNVLV

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [197-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 INDYILNVDE NCLIQYELYK NQLQNNNSNG KEWSCKRKSQ SSDDSDATVE EHISSSPQST  60
   61 GLDGDTTTMD EDEELNSKIK LINLKRFLID LSCWQYNLLK FELYEICNGM FSIINKFTNQ 120
  121 DQGPFLSMPI GNDINSNTQT QVFSIIINGI VNSPPSLVEV YKEQYGIVPF ILQVKDYNLE 180
  181 LQKKLQLAST 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 133.09691
Match: 1vin__
Description: Cyclin A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cyclin-dependent protein kinase regulator activity 6.12919068656167 bayes_pls_golite062009
cyclin-dependent protein kinase activity 3.81462270101479 bayes_pls_golite062009
protein kinase regulator activity 2.90083336559452 bayes_pls_golite062009
kinase regulator activity 2.84789294954357 bayes_pls_golite062009
binding 2.4204867358489 bayes_pls_golite062009
transcription regulator activity 1.86024002251052 bayes_pls_golite062009
protein binding 1.47106731485576 bayes_pls_golite062009
nucleic acid binding 1.23878797237176 bayes_pls_golite062009
DNA binding 1.18961617410859 bayes_pls_golite062009
enzyme regulator activity 1.07025055509935 bayes_pls_golite062009
protein kinase activity 0.957590284872001 bayes_pls_golite062009
kinase activity 0.919118452831504 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.806564872314381 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.671643397144957 bayes_pls_golite062009
hydrolase activity 0.62079213929979 bayes_pls_golite062009
protein serine/threonine kinase activity 0.567809158275482 bayes_pls_golite062009
transcription factor activity 0.567104149291415 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.56301729141837 bayes_pls_golite062009
kinase binding 0.451409627821468 bayes_pls_golite062009
transcription factor binding 0.396734044657235 bayes_pls_golite062009
enzyme binding 0.145967754156613 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [49-196]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSSKTKPDIK LIDQQPEMNP HQTREAIVTF LYQLSVMTRV SNGIFFHAVR FYDRYCSKRV  60
   61 VLKDQAKLVV GTCLWLAAKT WGGCNHIINN VSIPTGGRFY GPNPRARIPR LSELVHYCGG 120
  121 SDLFDESMFI QMERHILDTL NWDVYEPM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 133.09691
Match: 1vin__
Description: Cyclin A
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [387-546]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDLTRKIAVN SRYFDQNASS SSVSSPSTYS SGTNYTPMRN FSAQSDNSVF STTNIDHSSP  60
   61 ITPHMYTFNQ FKNESACDSA ISVSSLPNQT QNGNMPLSSN YQNMMLEERN KENRIPNSSS 120
  121 AEIPQRAKFM TTGIFQNTGE LTNRASSISL SLRNHNSSQL 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle