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View Structure Prediction Details

Protein: UBX4
Organism: Saccharomyces cerevisiae
Length: 416 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UBX4.

Description E-value Query
Range
Subject
Range
UBX4_YEAST - UBX domain-containing protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UBX4 PE=...
UBX4 - UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p
0.0 [1..416] [1..416]
ASPSCR1 - alveolar soft part sarcoma chromosome region, candidate 1
3.0E-44 [152..413] [250..548]
ASPC1_MOUSE - Tether containing UBX domain for GLUT4 OS=Mus musculus GN=Aspscr1 PE=1 SV=1
2.0E-42 [130..413] [249..545]
PUX10_ARATH - Plant UBX domain-containing protein 10 OS=Arabidopsis thaliana GN=PUX10 PE=2 SV=1
1.0E-35 [126..353] [246..480]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-35 [126..353] [232..466]

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Predicted Domain #1
Region A:
Residues: [1-126]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPMVTVKYNF QLFKCKVSLN STLNDVLHQS IQFFQLHTSS NDWSLIHLDK PVPLDLPWRL  60
   61 LNLPTGVNLE LSKSSNFPVA NKTNREDIPF NTIKIRFQIP GRDSVVKEMP SDQPIAPILR 120
  121 QMSGAA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 2.11588141989606 bayes_pls_golite062009
protein binding 1.75262085947538 bayes_pls_golite062009
small conjugating protein ligase activity 1.64626529520014 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.03640529353043 bayes_pls_golite062009
acid-amino acid ligase activity 0.778769490362734 bayes_pls_golite062009
nucleic acid binding 0.406724367405638 bayes_pls_golite062009
hydrolase activity 0.266557627363523 bayes_pls_golite062009
DNA binding 0.102021710653816 bayes_pls_golite062009
transcription regulator activity 0.0672274772804511 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [127-225]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDDFKIQVFS KIIEFKTIKD ENLTLENLGI QEPSSVRLIF NNTSHSEGIS ANSAIHPKQT  60
   61 PPTMTNPETV ASLPPHELHK PSVFLPSDEP LAVIKDQIE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [226-416]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEEDYELTVE QAKKYQKMLS SKAGTLGGPI LTKRLREQSA NNLPKKNKAI SECLLRVKFP  60
   61 DRSHIQIAFK PNEDMRTVYN VVSQFLIDEN MPFTLNQSHP FKPLAKDDKK LLDDLEFGSK 120
  121 TMLLFETNSN SNGPLIKAHL LEDAQKITHE TRTTPSVNTI NKSNPQGPSD NATSIKKTLN 180
  181 RVPKWMKLSK K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.522879
Match: 1jruA_
Description: p47
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.19381585790185 bayes_pls_golite062009
protein binding 1.89134588490127 bayes_pls_golite062009
small conjugating protein ligase activity 1.83465130904364 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.16468510691469 bayes_pls_golite062009
acid-amino acid ligase activity 0.919595189902044 bayes_pls_golite062009
nucleic acid binding 0.383121378043805 bayes_pls_golite062009
hydrolase activity 0.247201449341942 bayes_pls_golite062009
DNA binding 0.0840213088061073 bayes_pls_golite062009
transcription regulator activity 0.0485636215870291 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle