| Protein: | IOC4 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 475 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IOC4.
| Description | E-value | Query Range |
Subject Range |
|
|
5.0E-79 | [1..475] | [1..475] |
|
|
2.0E-38 | [5..401] | [502..936] |
|
|
2.0E-37 | [3..392] | [37..428] |
|
Region A: Residues: [1-103] |
1 11 21 31 41 51
| | | | | |
1 MSEAIFQPTD IVLAKVKGFS AWPAMIIPNE LIPDNILKTK PVSVHKGKSG SDKKANEDID 60
61 ADMESEARDR EQSEEEEDIE DFGESEANPE KFIIYTPVLK FRK
|
| Detection Method: |  |
| Confidence: | 23.638272 |
| Match: | PF00855 |
| Description: | PWWP domain |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| binding | 3.45928671861254 | bayes_pls_golite062009 |
| transcription regulator activity | 3.24722861476275 | bayes_pls_golite062009 |
| histone methyltransferase activity | 2.55219533482531 | bayes_pls_golite062009 |
| histone binding | 2.26545558774373 | bayes_pls_golite062009 |
| DNA binding | 2.10892266989425 | bayes_pls_golite062009 |
| histone-lysine N-methyltransferase activity | 2.01216822303077 | bayes_pls_golite062009 |
| protein-lysine N-methyltransferase activity | 2.01216822303077 | bayes_pls_golite062009 |
| lysine N-methyltransferase activity | 2.01216822303077 | bayes_pls_golite062009 |
| nucleic acid binding | 1.96501079412108 | bayes_pls_golite062009 |
| protein binding | 1.84773537446909 | bayes_pls_golite062009 |
| protein methyltransferase activity | 1.7489342678155 | bayes_pls_golite062009 |
| transcription repressor activity | 1.38876191465165 | bayes_pls_golite062009 |
| transcription factor binding | 1.32624006699374 | bayes_pls_golite062009 |
| transcription factor activity | 1.19430233104619 | bayes_pls_golite062009 |
| methylated histone residue binding | 1.1690628420074 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.15814615779914 | bayes_pls_golite062009 |
| N-methyltransferase activity | 0.883512085043854 | bayes_pls_golite062009 |
| chromatin binding | 0.563534016927931 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.422700451906002 | bayes_pls_golite062009 |
| transcription activator activity | 0.23424395939437 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.0867039973523847 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.0205412614883955 | bayes_pls_golite062009 |
|
Region A: Residues: [104-418] |
1 11 21 31 41 51
| | | | | |
1 NDTLKSTYCV KFFCDDSYIW VKPMDMKILT SEDCRKWLSG KQRKNKKLIP AYEMAMRGKN 60
61 GIDIWEFVEY GSYGKPDEEE YVEEEEEENE PEKKAIRPTR SSSRQRQKRA SETEKSEGGN 120
121 SNKRKRVTRS TRQQAIDASE EEEEEEEEKV QEAVRKRPQR TKTKKVVVSK TKPNPKTKAK 180
181 KEKPKPPKPI KYHFEDDEDW SIVGLGPQDL SIEKTMDPIA KKLSQKKNLE KHVEIKLDLE 240
241 DKLAGINKLL CDVLCSAINQ AVSIKDDFEI ILDELQIALD TRGSRNEFIT IFQSNNSLLL 300
301 NFRILFNLRK RELNK
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [419-475] |
1 11 21 31 41 51
| | | | | |
1 WDLWDRFQDI FKHIYSYQFI PDTEDWQLEQ NMEIEEMDRE KPSFSEDVKE EESKVGA
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.450 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.450 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.440 | g.34.1 | HIV-1 VPU cytoplasmic domain |
| View | Download | 0.440 | g.34.1 | HIV-1 VPU cytoplasmic domain |
| View | Download | 0.357 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.319 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.319 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.314 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.255 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.251 | a.118.1 | ARM repeat |
| View | Download | 0.244 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.237 | a.4.1 | Homeodomain-like |
| View | Download | 0.235 | a.60.3 | C-terminal domain of RNA polymerase alpha subunit |
| View | Download | 0.231 | a.4.1 | Homeodomain-like |
| View | Download | 0.231 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.225 | a.164.1 | C-terminal domain of DFF45/ICAD (DFF-C domain) |
| View | Download | 0.215 | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.211 | d.48.1 | RecA protein, C-terminal domain |
| View | Download | 0.202 | a.4.6 | C-terminal effector domain of the bipartite response regulators |
