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View Structure Prediction Details

Protein: TAF4
Organism: Saccharomyces cerevisiae
Length: 388 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TAF4.

Description E-value Query
Range
Subject
Range
TAF4 - TFIID subunit (48 kDa), involved in RNA polymerase II transcription initiation; potential Cdc28p sub...
TAF4_YEAST - Transcription initiation factor TFIID subunit 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2...
0.0 [1..388] [1..388]
gi|25403330, gi|... - gi|6693034|gb|AAF24960.1|AC012375_23 T22C5.17 [Arabidopsis thaliana], pir||A86402 protein T22C5.17 [...
0.0 [15..386] [329..693]
taf4 - transcription factor TFIID complex subunit Taf4
TAF4_SCHPO - Transcription initiation factor TFIID subunit 4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 2484...
1.0E-78 [59..388] [1..365]
FBpp0311865, Taf... - The gene TBP-associated factor 4 is referred to in FlyBase by the symbol Dmel\Taf4 (CG5444, FBgn0010...
gi|345516 - gi|345516|pir||A45183 TBP-associated factor TFIID - fruit fly (Drosophila sp.)
7.0E-76 [23..385] [549..921]
gi|15375062 - gi|15375062|gb|AAK94779.1| TATA-binding protein associated factor TAFII135 [Mus musculus]
2.0E-70 [4..384] [244..659]
TAF4 - TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
5.0E-70 [6..385] [676..1083]
gi|14140138 - gi|14140138|emb|CAC39055.1| putative protein [Oryza sativa]
1.0E-68 [2..386] [257..684]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANSPKKPSD GTGVSASDTP KYQHTVPETK PAFNLSPGKA SELSHSLPSP SQIKSTAHVS  60
   61 STHNDAAGNT DDSVLPKNVS PTTNLRVESN GDTNNM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [97-318]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FSSPAGLALP KKDDKKKNKG TSKADSKDGK ASNSSGQNAQ QQSDPNKMQD VLFSAGIDVR  60
   61 EEEALLNSSI NASKSQVQTN NVKIPNHLPF LHPEQVSNYM RKVGKEQNFN LTPTKNPEIL 120
  121 DMMSSACENY MRDILTNAIV ISRHRRKAVK INSGRRSEVS AALRAIALIQ KKEEERRVKK 180
  181 RIALGLEKED YENKIDSEET LHRASNVTAG LRAGSKKQYG WL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.39794
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 9.25279783093877 bayes_pls_golite062009
DNA binding 4.49118409263799 bayes_pls_golite062009
nucleic acid binding 4.35201412176948 bayes_pls_golite062009
transcription regulator activity 4.08606081850613 bayes_pls_golite062009
transcription initiation factor activity 3.96621818094279 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.28941584139552 bayes_pls_golite062009
binding 3.27510691458843 bayes_pls_golite062009
transcription factor activity 2.51581622888695 bayes_pls_golite062009
transcription activator activity 1.25487495162413 bayes_pls_golite062009
transcription factor binding 1.15204005455906 bayes_pls_golite062009
transcription coactivator activity 1.1297723528047 bayes_pls_golite062009
nucleotidyltransferase activity 1.10331930589736 bayes_pls_golite062009
protein binding 1.07873333188144 bayes_pls_golite062009
transcription cofactor activity 1.01502031330902 bayes_pls_golite062009
transcription repressor activity 0.72554769377984 bayes_pls_golite062009
sequence-specific DNA binding 0.0852726470007639 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.0792897588268993 bayes_pls_golite062009
transcription corepressor activity 0.0736756545988504 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [319-388]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSSVNKPTSL GAKSSGKVAS DITARGESGL KFREAREEPG IVMRDLLFAL ENRRNSVQTI  60
   61 ISKGYAKIRD 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle