| Protein: | PIF1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 859 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PIF1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..859] | [1..857] |
|
|
0.0 | [127..808] | [70..830] |
|
|
7.0E-93 | [83..783] | [171..800] |
|
|
2.0E-92 | [83..783] | [171..800] |
|
Region A: Residues: [1-133] |
1 11 21 31 41 51
| | | | | |
1 MPKWIRSTLN HIIPRRPFIC SFNSFLLLKN VSHAKLSFSM SSRGFRSNNF IQAQLKHPSI 60
61 LSKEDLDLLS DSDDWEEPDC IQLETEKQEK KIITDIHKED PVDKKPMRDK NVMNFINKDS 120
121 PLSWNDMFKP SII
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.490 | a.40.1 | Calponin-homology domain, CH-domain |
| View | Download | 0.337 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.448 | c.25.1 | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| View | Download | 0.322 | d.20.1 | UBC-like |
| View | Download | 0.320 | c.55.1 | Actin-like ATPase domain |
| View | Download | 0.300 | d.32.1 | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |
| View | Download | 0.292 | d.32.1 | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |
| View | Download | 0.283 | a.40.1 | Calponin-homology domain, CH-domain |
| View | Download | 0.278 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.266 | c.2.1 | NAD(P)-binding Rossmann-fold domains |
|
Region A: Residues: [134-236] |
1 11 21 31 41 51
| | | | | |
1 QPPQLISENS FDQSSQKKSR STGFKNPLRP ALKKESSFDE LQNNSISQER SLEMINENEK 60
61 KKMQFGEKIA VLTQRPSFTE LQNDQDDSNL NPHNGVKVKI PIC
|
| Detection Method: | |
| Confidence: | 3.221849 |
| Match: | 1fts__ |
| Description: | Signal recognition particle receptor, FtsY; GTPase domain of the signal recognition particle receptor FtsY |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.5815673740955 | bayes_pls_golite062009 |
| nucleic acid binding | 2.18361843860268 | bayes_pls_golite062009 |
| DNA binding | 1.93283541470819 | bayes_pls_golite062009 |
| transcription regulator activity | 1.86711849769952 | bayes_pls_golite062009 |
| pyrophosphatase activity | 1.22434861137232 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 1.00145424382707 | bayes_pls_golite062009 |
| catalytic activity | 0.942640875796745 | bayes_pls_golite062009 |
| helicase activity | 0.930824665371921 | bayes_pls_golite062009 |
| transcription factor activity | 0.737538356360809 | bayes_pls_golite062009 |
| transcription repressor activity | 0.723025725174193 | bayes_pls_golite062009 |
| DNA helicase activity | 0.525155854231881 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 0.364091846246035 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 0.364091846246035 | bayes_pls_golite062009 |
| protein binding | 0.201869978778282 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.164280007805333 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 0.0142902906813618 | bayes_pls_golite062009 |
|
Region A: Residues: [237-515] |
1 11 21 31 41 51
| | | | | |
1 LSKEQESIIK LAENGHNIFY TGSAGTGKSI LLREMIKVLK GIYGRENVAV TASTGLAACN 60
61 IGGITIHSFA GIGLGKGDAD KLYKKVRRSR KHLRRWENIG ALVVDEISML DAELLDKLDF 120
121 IARKIRKNHQ PFGGIQLIFC GDFFQLPPVS KDPNRPTKFA FESKAWKEGV KMTIMLQKVF 180
181 RQRGDVKFID MLNRMRLGNI DDETEREFKK LSRPLPDDEI IPAELYSTRM EVERANNSRL 240
241 SKLPGQVHIF NAIDGGALED EELKERLLQN FLAPKELHL
|
| Detection Method: | |
| Confidence: | 37.69897 |
| Match: | 1uaaA_ |
| Description: | DEXX box DNA helicase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [516-634] |
1 11 21 31 41 51
| | | | | |
1 KVGAQVMMVK NLDATLVNGS LGKVIEFMDP ETYFCYEALT NDPSMPPEKL ETWAENPSKL 60
61 KAAMEREQSD GEESAVASRK SSVKEGFAKS DIGEPVSPLD SSVFDFMKRV KTDDEVVLE
|
| Detection Method: | |
| Confidence: | 37.69897 |
| Match: | 1uaaA_ |
| Description: | DEXX box DNA helicase |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [635-778] |
1 11 21 31 41 51
| | | | | |
1 NIKRKEQLMQ TIHQNSAGKR RLPLVRFKAS DMSTRMVLVE PEDWAIEDEN EKPLVSRVQL 60
61 PLMLAWSLSI HKSQGQTLPK VKVDLRRVFE KGQAYVALSR AVSREGLQVL NFDRTRIKAH 120
121 QKVIDFYLTL SSAESAYKQL EADE
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.435 | N/A | N/A | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.402 | 0.018 | telomere maintenance | d.32.1 | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |
| View | Download | 0.329 | 0.003 | telomere maintenance | c.34.1 | DFP DNA/pantothenate metabolism flavoprotein |
| View | Download | 0.375 | 0.003 | telomere maintenance | d.60.1 | Probable bacterial effector-binding domain |
| View | Download | 0.336 | 0.002 | telomere maintenance | b.64.1 | Mannose 6-phosphate receptor domain |
| View | Download | 0.325 | N/A | N/A | d.218.1 | Nucleotidyltransferase |
| View | Download | 0.297 | N/A | N/A | d.24.1 | Pili subunits |
| View | Download | 0.285 | N/A | N/A | d.162.1 | LDH C-terminal domain-like |
| View | Download | 0.278 | N/A | N/A | d.162.1 | LDH C-terminal domain-like |
| View | Download | 0.276 | N/A | N/A | c.3.1 | FAD/NAD(P)-binding domain |
| View | Download | 0.264 | N/A | N/A | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.255 | N/A | N/A | b.29.1 | Concanavalin A-like lectins/glucanases |
| View | Download | 0.249 | N/A | N/A | d.122.1 | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase |
| View | Download | 0.238 | N/A | N/A | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.218 | N/A | N/A | d.162.1 | LDH C-terminal domain-like |
| View | Download | 0.212 | N/A | N/A | b.55.1 | PH domain-like |
|
Region A: Residues: [779-859] |
1 11 21 31 41 51
| | | | | |
1 QVKKRKLDYA PGPKYKAKSK SKSNSPAPIS ATTQSNNGIA AMLQRHSRKR FQLKKESNSN 60
61 QVHSLVSDEP RGQDTEDHIL E
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.289 | a.3.1 | Cytochrome c |
| View | Download | 0.543 | a.64.1 | Saposin |
| View | Download | 0.315 | a.2.3 | Chaperone J-domain |
| View | Download | 0.533 | a.163.1 | Crustacean CHH/MIH/GIH neurohormone |
| View | Download | 0.289 | a.4.1 | Homeodomain-like |
| View | Download | 0.235 | a.4.3 | ARID-like |
| View | Download | 0.218 | a.7.6 | Ribosomal protein S20 |
