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View Structure Prediction Details

Protein: BAS1
Organism: Saccharomyces cerevisiae
Length: 811 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BAS1.

Description E-value Query
Range
Subject
Range
gi|151941639 - gi|151941639|gb|EDN60002.1| transcription factor [Saccharomyces cerevisiae YJM789]
BAS1_YEAST - Myb-like DNA-binding protein BAS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BAS1 P...
BAS1 - Myb-related transcription factor involved in regulating basal and induced expression of genes of the...
0.0 [1..811] [1..811]
gi|1872200, gi|1... - gi|1872200|gb|AAB49034.1| alternatively spliced product using exon 13A, gi|119568359|gb|EAW47974.1| ...
1.0E-80 [9..418] [5..419]
gi|1333884 - gi|1333884|emb|CAA26551.1| unnamed protein product [Mus musculus]
2.0E-79 [10..418] [12..431]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-78 [9..418] [5..419]
MYB_BOVIN - Transcriptional activator Myb OS=Bos taurus GN=MYB PE=2 SV=1
1.0E-77 [9..418] [5..419]

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Predicted Domain #1
Region A:
Residues: [1-113]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNISTKDIR KSKPKRGSGF DLLEVTESLG YQTHRKNGRN SWSKDDDNML RSLVNESAKE  60
   61 LGYENGLEDV KTIQQSNHLS KCIAWDVLAT RFKHTVRTSK DVRKRWTGSL DPN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 202.751666
Match: 1h88C_
Description: c-Myb, DNA-binding domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.41876985649951 bayes_pls_golite062009
nucleic acid binding 4.09724849396574 bayes_pls_golite062009
transcription factor activity 3.86239731611043 bayes_pls_golite062009
binding 3.55096238224843 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.16896789933192 bayes_pls_golite062009
sequence-specific DNA binding 2.32406445003946 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.73068440195944 bayes_pls_golite062009
chromatin binding 1.50301355818265 bayes_pls_golite062009
protein binding 1.44503155604344 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
transcription corepressor activity 0.12996981272574 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [114-164]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKKGKWTQEE DEQLLKAYEE HGPHWLSISM DIPGRTEDQC AKRYIEVLGP G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 202.751666
Match: 1h88C_
Description: c-Myb, DNA-binding domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [165-226]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKGRLREWTL EEDLNLISKV KAYGTKWRKI SSEMEFRPSL TCRNRWRKII TMVVRGQASE  60
   61 VI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 202.751666
Match: 1h88C_
Description: c-Myb, DNA-binding domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [227-459]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKAIKENKNI DMTDGKLRQH PIADSDIRSD STPNKEEQLQ LSQQNNPSLI KQDILNVKEN  60
   61 ESSKLPRLKD NDGPILNDSK PQALPPLKEI SAPPPIRMTQ VGQTHTSGSI RSKVSLPIEG 120
  121 LSQMNKQSPG GISDSPQTSL PPAFNPASLD EHMMNSNSIS DSPKHAYSTV KTREPNSSST 180
  181 QWKFTLKDGQ GLSISNGTID STKLVKELVD QAKKYSLKIS IHQHIHNHYV TST

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [460-811]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DHPVSSNTGL SNIGNINGNP LLMDSFPHMG RQLGNGLPGL NSNSDTFNPE YRTSLDNMDS  60
   61 DFLSRTPNYN AFSLEATSHN PADNANELGS QSNRETNSPS VFYPQANTLI PTNSTATNNE 120
  121 IIQGNVSANS MSPNFNGTNG KAPSSTASYT TSGSEMPPDV GPNRIAHFNY LPPTIRPHLG 180
  181 SSDATRGADL NKLLNPSPNS VRSNGSKTKK KEKRKSESSQ HHSSSSVTTN KFNHIDQSEI 240
  241 SRTTSRSDTP LRDEDGLDFW ETLRSLATTN PNPPVEKSAE NDGAKPQVVH QGIGSHTEDS 300
  301 SLGSHSGGYD FFNELLDKKA DTLHNEAKKT SEHDMTSGGS TDNGSVLPLN PS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle