YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: APL2
Organism: Saccharomyces cerevisiae
Length: 726 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for APL2.

Description E-value Query
Range
Subject
Range
APL2 - Beta-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; invol...
AP1B1_YEAST - AP-1 complex subunit beta-1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=APL2 PE=1 SV...
0.0 [1..726] [1..726]
AP2B1 - adaptor-related protein complex 2, beta 1 subunit
gi|149724034 - gi|149724034|ref|XP_001503976.1| PREDICTED: similar to beta-chain clathrin associated protein comple...
AP2B1_RAT - AP-2 complex subunit beta OS=Rattus norvegicus GN=Ap2b1 PE=1 SV=1
gi|73966773 - gi|73966773|ref|XP_867698.1| PREDICTED: similar to Adapter-related protein complex 2 beta 1 subunit ...
gi|114668040, gi... - gi|114668042|ref|XP_001174162.1| PREDICTED: adaptor-related protein complex 2, beta 1 subunit isofor...
gi|168277614 - gi|168277614|dbj|BAG10785.1| AP-2 complex subunit beta-1 [synthetic construct]
0.0 [25..726] [12..694]
AP2B1_MOUSE - AP-2 complex subunit beta OS=Mus musculus GN=Ap2b1 PE=1 SV=1
0.0 [25..726] [12..694]
AP1B1_RAT - AP-1 complex subunit beta-1 OS=Rattus norvegicus GN=Ap1b1 PE=1 SV=1
0.0 [20..726] [7..706]
apb-1 - status:Confirmed UniProt:Q9N4F3 protein_id:AAF36038.2
0.0 [20..685] [7..650]
gi|220952014 - gi|220952014|gb|ACL88550.1| Bap-PA [synthetic construct]
Bap-PA - The gene Ã?ŽÃ?’ Adaptin is referred to in FlyBase by the symbol Dmel\Bap (CG12532, FBgn001...
0.0 [20..642] [7..635]
APBLC_ARATH - Beta-adaptin-like protein C OS=Arabidopsis thaliana GN=BETAC-AD PE=1 SV=2
0.0 [20..665] [9..645]

Back

Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPLDKRIKK FLKDSIRIAP KISGKGELSE LRTGLVSQYP QTRKDAIKKT IQQMTLGKDV  60
   61 SSLFPDVLKN IATIDVEQKK LVYLYVMNYA ETHPELCILA VNT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1164.0
Match: 1gw5B_
Description: Adaptin beta subunit N-terminal fragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [104-210]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FITDAQDPNP LIRCMAIRTM SMIRVDKILE YIETPLRRTL HDDNAYVRKT AVICVAKLFQ  60
   61 LNKDLCVELG VVEDLVNALD DSNPLVIANA TAALIEIHNM DMDAVDL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1164.0
Match: 1gw5B_
Description: Adaptin beta subunit N-terminal fragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [211-345]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSLIQSHVSQ FLLALNECTE WARIIILGTL SEYSAKDSLE AQDIIDRVTA HLQHVNPAVV  60
   61 LATIKVIVRN LPQIEYSSNS LIMKRLSSAF VSLMSTPPEM QYVALKNIRI ILEKYPELLT 120
  121 KELRIFYVKF NDPLY

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [577-633]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPEVLEKLLM ELGTISSIYF KPDSNRRKGK KYVQNIVKGK HIEELESMAK NEISSKA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1164.0
Match: 1gw5B_
Description: Adaptin beta subunit N-terminal fragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [346-440]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VKLEKIDILV RLVDPSNLKQ CTLLLTELKE YAMEYEPEFV SRAIQALSQL GIKYAQESFV  60
   61 SKVLDILLEL LERQDTIKDD CCISLCDLLR HCPGN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1164.0
Match: 1gw5B_
Description: Adaptin beta subunit N-terminal fragment
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [441-576]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKMAKQVCAV FNTWSNPEVL LQSDIAKCNY VWLLGQHPNN FSDLESKINI FIENFVQEEA  60
   61 LTQMSLLMTI VRLHATLTGS MLQSVLELAT QQTHELDVRD MAMMYWRCLS MPNNESLVND 120
  121 LCQNKLPMIS NTLEKF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1164.0
Match: 1gw5B_
Description: Adaptin beta subunit N-terminal fragment
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [634-726]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDDVLLDFDE RDDVTNTNAG MLNTLTTLGD LDDLFDFGPS EDATQINTND TKAVQGLKEL  60
   61 KLGGDSNGIS SGGKNNPDVS GGNIVSQDLL DLF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle