| Protein: | UFD4 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1483 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UFD4.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1483] | [1..1483] |
|
|
0.0 | [52..1483] | [26..1502] |
|
|
0.0 | [641..1483] | [1046..1992] |
|
|
0.0 | [894..1482] | [437..956] |
|
|
0.0 | [894..1482] | [364..886] |
|
Region A: Residues: [1-72] |
1 11 21 31 41 51
| | | | | |
1 MSENNSHNLD EHESHSENSD YMMDTQVEDD YDEDGHVQGE YSYYPDEDED EHMLSSVGSF 60
61 EADDGEDDDN DY
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.332 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.348 | d.58.5 | GlnB-like |
| View | Download | 0.332 | a.37.1 | A DNA-binding domain in eukaryotic transcription factors |
| View | Download | 0.311 | d.58.5 | GlnB-like |
| View | Download | 0.305 | d.50.3 | PI-Pfui intein middle domain |
| View | Download | 0.276 | d.71.1 | Cell division protein MinE topological specificity domain |
| View | Download | 0.264 | d.58.12 | eEF-1beta-like |
| View | Download | 0.227 | d.58.14 | Ribosomal protein S6 |
| View | Download | 0.214 | b.43.3 | Translation proteins |
| View | Download | 0.201 | d.58.8 | Viral DNA-binding domain |
|
Region A: Residues: [73-158] |
1 11 21 31 41 51
| | | | | |
1 HHEDDSGLLY GYHRTQNGSD EDRNEEEDGL ERSHDNNEFG SNPLHLPDIL ETFAQRLEQR 60
61 RQTSEGLGQH PVGRTLPEIL SMIGGR
|
| Detection Method: | |
| Confidence: | 2.09691 |
| Match: | 1qgkB_ |
| Description: | STRUCTURE OF IMPORTIN BETA BOUND TO THE IBB DOMAIN OF IMPORTIN ALPHA |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.86831493830281 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.16002474842826 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 1.81334106667983 | bayes_pls_golite062009 |
| protein binding | 1.63705839411934 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 1.4929266246031 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 1.21098157405785 | bayes_pls_golite062009 |
| nucleic acid binding | 1.13208464017585 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 1.1051743850645 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 1.03004697855361 | bayes_pls_golite062009 |
| protein transporter activity | 0.942980596902738 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.820796192007653 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.520600504671387 | bayes_pls_golite062009 |
| kinase activity | 0.49215920455609 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.399777570162093 | bayes_pls_golite062009 |
| protein kinase activity | 0.304524178731686 | bayes_pls_golite062009 |
| transferase activity | 0.23030640245878 | bayes_pls_golite062009 |
| transcription regulator activity | 0.221086931523202 | bayes_pls_golite062009 |
| DNA binding | 0.171056781378569 | bayes_pls_golite062009 |
|
Region A: Residues: [159-294] |
1 11 21 31 41 51
| | | | | |
1 MERSAESSAR NERISKLIEN TGNASEDPYI AMESLKELSE NILMMNQMVV DRIIPMETLI 60
61 GNIAAILSDK ILREELELQM QACRCMYNLF EVCPESISIA VDEHVIPILQ GKLVEISYID 120
121 LAEQVLETVE YISRVH
|
| Detection Method: | |
| Confidence: | 113.0 |
| Match: | 1ejlI_ |
| Description: | Importin alpha |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [295-343] |
1 11 21 31 41 51
| | | | | |
1 GRDILKTGQL SIYVQFFDFL TIHAQRKAIA IVSNACSSIR TDDFKTIVE
|
| Detection Method: | |
| Confidence: | 113.0 |
| Match: | 1ejlI_ |
| Description: | Importin alpha |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [344-457] |
1 11 21 31 41 51
| | | | | |
1 VLPTLKPIFS NATDQPILTR LVNAMYGICG ALHGVDKFET LFSLDLIERI VQLVSIQDTP 60
61 LENKLKCLDI LTVLAMSSDV LSRELREKTD IVDMATRSFQ HYSKSPNAGL HETL
|
| Detection Method: | |
| Confidence: | 113.0 |
| Match: | 1ejlI_ |
| Description: | Importin alpha |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| proline-rich region binding | 2.77294348104858 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 2.59532734096591 | bayes_pls_golite062009 |
| binding | 2.42370909657521 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 2.41863405676058 | bayes_pls_golite062009 |
| transcription factor binding | 1.96854466908038 | bayes_pls_golite062009 |
| histone methyltransferase activity | 1.90194027965368 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 1.6967322982151 | bayes_pls_golite062009 |
| protein binding | 1.36920369713546 | bayes_pls_golite062009 |
| transcription regulator activity | 1.32260772865135 | bayes_pls_golite062009 |
| lysine N-methyltransferase activity | 1.14806422628668 | bayes_pls_golite062009 |
| protein-lysine N-methyltransferase activity | 1.14806422628668 | bayes_pls_golite062009 |
| histone-lysine N-methyltransferase activity | 1.14806422628668 | bayes_pls_golite062009 |
| protein methyltransferase activity | 1.121001087082 | bayes_pls_golite062009 |
| transcription activator activity | 1.06699689139974 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.9852373289585 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.91931537361124 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 0.568363753662296 | bayes_pls_golite062009 |
| transferase activity | 0.381275448590978 | bayes_pls_golite062009 |
| transcription repressor activity | 0.2295693429366 | bayes_pls_golite062009 |
| catalytic activity | 0.210712504691113 | bayes_pls_golite062009 |
| histone methyltransferase activity (H3-K36 specific) | 0.173723075520888 | bayes_pls_golite062009 |
|
Region A: Residues: [458-568] |
1 11 21 31 41 51
| | | | | |
1 IYVPNSLLIS ISRFIVVLFP PEDERILSAD KYTGNSDRGV ISNQEKFDSL VQCLIPILVE 60
61 IYTNAADFDV RRYVLIALLR VVSCINNSTA KAINDQLIKL IGSILAQKET A
|
| Detection Method: | |
| Confidence: | 113.0 |
| Match: | 1ejlI_ |
| Description: | Importin alpha |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [569-670] |
1 11 21 31 41 51
| | | | | |
1 SNANGTYSSE AGTLLVGGLS LLDLICKKFS ELFFPSIKRE GIFDLVKDLS VDFNNIDLKE 60
61 DGNENISLSD EEGDLHSSIE ECDEGDEEYD YEFTDMEIPD SV
|
| Detection Method: | |
| Confidence: | 113.0 |
| Match: | 1ejlI_ |
| Description: | Importin alpha |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [671-973] |
1 11 21 31 41 51
| | | | | |
1 KPKKISIHIF RTLSLAYIKN KGVNLVNRVL SQMNVEQEAI TEELHQIEGV VSILENPSTP 60
61 DKTEEDWKGI WSVLKKCIFH EDFDVSGFEF TSTGLASSIT KRITSSTVSH FILAKSFLEV 120
121 FEDCIDRFLE ILQSALTRLE NFSIVDCGLH DGGGVSSLAK EIKIKLVYDG DASKDNIGTD 180
181 LSSTIVSVHC IASFTSLNEF LRHRMVRMRF LNSLIPNLTS SSTEADREEE ENCLDHMRKK 240
241 NFDFFYDNEK VDMESTVFGV IFNTFVRRNR DLKTLWDDTH TIKFCKSLEG NNRESEAAEE 300
301 ANE
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [974-1092] |
1 11 21 31 41 51
| | | | | |
1 GKKLRDFYKK REFAQVDTGS SADILTLLDF LHSCGVKSDS FINSKLSAKL ARQLDEPLVV 60
61 ASGALPDWSL FLTRRFPFLF PFDTRMLFLQ CTSFGYGRLI QLWKNKSKGS KDLRNDEAL
|
| Detection Method: | |
| Confidence: | 3.09691 |
| Match: | 1i5hW_ |
| Description: | Ubiquitin ligase NEDD4 WWIII domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1093-1138] |
1 11 21 31 41 51
| | | | | |
1 QQLGRITRRK LRISRKTIFA TGLKILSKYG SSPDVLEIEY QEEAGT
|
| Detection Method: | |
| Confidence: | 323.0103 |
| Match: | 1c4zA_ |
| Description: | Ubiquitin-protein ligase E3a, Hect catalytic domain (E6ap) |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1139-1263] |
1 11 21 31 41 51
| | | | | |
1 GLGPTLEFYS VVSKYFARKS LNMWRCNSYS YRSEMDVDTT DDYITTLLFP EPLNPFSNNE 60
61 KVIELFGYLG TFVARSLLDN RILDFRFSKV FFELLHRMST PNVTTVPSDV ETCLLMIELV 120
121 DPLLA
|
|
Region B: Residues: [1318-1360] |
1 11 21 31 41 51
| | | | | |
1 IDQILGKGIE KQLKAFIEGF SKVFSYERML ILFPDELVDI FGR
|
| Detection Method: | |
| Confidence: | 323.0103 |
| Match: | 1c4zA_ |
| Description: | Ubiquitin-protein ligase E3a, Hect catalytic domain (E6ap) |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1264-1317] |
1 11 21 31 41 51
| | | | | |
1 KSLKYIVANK DDNMTLESLS LTFTVPGNDD IELIPGGCNK SLNSSNVEEY IHGV
|
|
Region B: Residues: [1361-1483] |
1 11 21 31 41 51
| | | | | |
1 VEEDWSMATL YTNLNAEHGY TMDSSIIHDF ISIISAFGKH ERRLFLQFLT GSPKLPIGGF 60
61 KSLNPKFTVV LKHAEDGLTA DEYLPSVMTC ANYLKLPKYT SKDIMRSRLC QAIEEGAGAF 120
121 LLS
|
| Detection Method: | |
| Confidence: | 323.0103 |
| Match: | 1c4zA_ |
| Description: | Ubiquitin-protein ligase E3a, Hect catalytic domain (E6ap) |
| Matching Structure (courtesy of the PDB): |
|
