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Protein Overview: UPL4_ARATH

General Information:
Name(s) found: UPL4_ARATH [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • E3 ubiquitin-protein ligase UPL4 OS=Arabidopsis thaliana GN=UPL4 PE=3 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 1502 amino acids

    Gene Ontology:
    Cellular Component: ubiquitin ligase complex [ISS]
    Biological Process: protein ubiquitination [ISS]
    Molecular Function: ubiquitin-protein ligase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENRGQKRME VVEELPADKR ACNSQDFRPS TSGSSVQAQA NDTNPGHENV DADMDTSSSA  60
   61 SPSSRSDEEE QEEQDKEDSD YGSCDSDEED PRQRVLQDYQ RQRSSGDHGK LKSLLLNLTG 120
  121 ETDPSGQLSR LTELCEVLSF STEESLSSVM ANMLSPVLVK LAKHENNADI MLLAIRAITY 180
  181 LCDVYPPSVE FLVRHDTIPA LCQRLLTIEY LDVAEQCLQA LEKISRDEPV ACLNAGAIMA 240
  241 VLSFIDFFST SIQRVAISTV VNICKQLSSE SPSPFMDAVP ILCTLLQYED RQLVENVAIC 300
  301 LTKIADQASE SPAMLDQLCR HGLINESTHL LNLNSRTTLS QPVYNGVIGM LRKLSSGSAL 360
  361 AFRTLYELNI GYSLKEIMST YDISHSVSST HPINACSNQV HEVLKLVIEL LPASPVEDNQ 420
  421 LASEKESFLV NQPDLLQQFG RDMLPVMIQV LNSGANVYVS YGCLSAIHKL TCLSKSGDIV 480
  481 ELLKNTNMSS VLAGILSRKD HHVIVVALQV AEVLLEKYRD TFLNSFIKEG VFFAIEALLS 540
  541 SDRGQQNQGS ADLSQKPVTK EIVKCLCQSF ERSLSSSSQT CKIEKDSVYV LATRIKEGFF 600
  601 GPEVFNSEKG LTDVLQNLKN LSVALSELMT VPIDAHVLHD EKFFSIWNQI MERLNGRESV 660
  661 STFEFIESGV VKSLASYLSN GLYQRKLSKG GPECDSLPFI GKRFEVFTRL LWSDGEATSS 720
  721 LLIQKLQNSL SSLENFPIVL SQFLKQKNSF AAIPNGRCTS YPCLKVRFLK AEGETSLRDY 780
  781 SQDFVTVDPL CYLDAVDQYL WPKVNIEPID SVEAKDQAIE CQSSQLQSTS ISCQAESSSP 840
  841 MEIDSESSDA SQLQGSQVED QTQLPGQQNA SSSETSSEKE DAVPRLLFRL EGLELDRSLT 900
  901 VYQAILLHKL KSESEATNDS KLSGPHNITY ERSAQLGDSR ENLFPPGSME DDEYRPFLSY 960
  961 LFTHRLALRL KGSSHPPYDI LFLLKSLEGM NRFLFHLISL ERINAFGEGR LENLDDLRVQ1020
 1021 VRPVPHSEFV SSKLTEKLEQ QLRDSFAVST CGLPPWFNDL MDSCPCLFSF EAKSKYFRLA1080
 1081 AFGSQKIRHH PQHLSSSNVH GEARPVTGSL PRKKFLACRE NILESAAKMM ELYGNQKVVI1140
 1141 EVEYSEEVGT GLGPTLEFYT LVSRAFQNPD LGMWRNDCSF IVGKPVEHSG VLASSSGLFP1200
 1201 RPWSGTSTTS DVLQKFVLLG TVVAKALQDG RVLDLPLSKA FYKLILGQEL SSFDIHFVDP1260
 1261 ELCKTLVELQ ALVRRKKLFA EAHGDSGAAK CDLSFHGTKI EDLCLEFALP GYTDYDLAPY1320
 1321 SANDMVNLDN LEEYIKGIVN ATVCNGIQKQ VEAFRSGFNQ VFSIEHLRIF NEEELETMLC1380
 1381 GECDLFSMNE VLDHIKFDHG YTSSSPPVEY LLQILHEFDR EQQRAFLQFV TGSPRLPHGG1440
 1441 LASLSPKLTI VRKHGSDSSD TDLPSVMTCA NYLKLPPYSS KEKMKEKLIY AITEGQGSFH1500
 1501 LS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..582] PSI-BLAST 98.221849 Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
    2 View Details [583..634] PSI-BLAST 19.0 AP1 clathrin adaptor core
    3 View Details [635..836] deduced N/A No confident structure predictions are available.
    4 View Details [837..914] deduced N/A No confident structure predictions are available.
    5 View Details [915..1023] deduced N/A No confident structure predictions are available.
    6 View Details [1024..1502] PSI-BLAST 110.0 Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.78

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle