| Protein: | VPS70 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 811 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VPS70.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..811] | [1..811] |
|
|
0.0 | [77..811] | [10..742] |
|
|
0.0 | [68..811] | [6..741] |
|
|
0.0 | [68..811] | [6..740] |
|
|
0.0 | [77..811] | [10..742] |
|
Region A: Residues: [1-124] |
1 11 21 31 41 51
| | | | | |
1 MRMIQRERKR EKEEGQLKER TVVNMADPDD NEAEATGLQQ YSGETTRDDN EESMNDSFTL 60
61 TSRNRGRSNT ISSIVSGYEI MKEHMDKEKF MYLILASLLL YMGFVAAFAP RTSLSRDFRR 120
121 FHSS
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.260 | a.39.1 | EF-hand |
| View | Download | 0.440 | a.174.1 | Double Clp-N motif |
| View | Download | 0.220 | a.90.1 | Transcription factor STAT-4 N-domain |
| View | Download | 0.211 | f.31.1 | Photosystem I reaction center subunit XI, PsaL |
| View | Download | 0.440 | a.174.1 | Double Clp-N motif |
| View | Download | 0.260 | a.39.1 | EF-hand |
| View | Download | 0.220 | a.90.1 | Transcription factor STAT-4 N-domain |
| View | Download | 0.211 | f.31.1 | Photosystem I reaction center subunit XI, PsaL |
|
Region A: Residues: [125-215] |
1 11 21 31 41 51
| | | | | |
1 RLTNAEVYRI YLNSLQQENR AKEHVYKYAG YMSNGASDSS TFKYTLDEFL DMGYKPKVEK 60
61 YYPWIGEPVD TNVAPLENGK VVYEASMIED R
|
|
Region B: Residues: [335-361] |
1 11 21 31 41 51
| | | | | |
1 SDTPGDPTTP GYPSKDSDTE HMSPVGR
|
|
Region C: Residues: [419-652] |
1 11 21 31 41 51
| | | | | |
1 YNIKEMSSVE VSIPGIFTEG EIIIGAHRDS LASSSAGDAN SGSAILLEIA RGMSKLLKHG 60
61 WKPLRPIKLI SWDGERSGLL GSTDYAEAHA AILRRRALVY LNLDNAISGT NFHCKANPLL 120
121 QDVIYEAAKL TEFNGHEDWS LFDHWKYTSN ATISLLDGLS SYTSFQYHLG VPAAHFQFNA 180
181 NDTSGAVYHS NSVFDSPTWL EKFTNSDYKL HNTMAMFVGL TTLMLSENEL ARFN
|
| Detection Method: | |
| Confidence: | 359.9897 |
| Match: | 1de4C_ |
| Description: | Transferrin receptor ectodomain, C-terminal domain; Transferrin receptor ectodomain, apical domain; Transferrin receptor ectodomain, protease-like domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| peptidase activity | 3.33010352069253 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 2.96046345079997 | bayes_pls_golite062009 |
| hydrolase activity | 2.61327242243519 | bayes_pls_golite062009 |
| exopeptidase activity | 1.70361627875478 | bayes_pls_golite062009 |
| catalytic activity | 1.3989281287879 | bayes_pls_golite062009 |
| metallopeptidase activity | 1.34087538226325 | bayes_pls_golite062009 |
| carboxypeptidase activity | 0.891655769761122 | bayes_pls_golite062009 |
| metalloexopeptidase activity | 0.619120257877893 | bayes_pls_golite062009 |
| signal transducer activity | 0.267328041739913 | bayes_pls_golite062009 |
| molecular transducer activity | 0.267328041739913 | bayes_pls_golite062009 |
| binding | 0.228948932725967 | bayes_pls_golite062009 |
| metallocarboxypeptidase activity | 0.180859448845431 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.137810390418952 | bayes_pls_golite062009 |
| receptor activity | 0.0721997980843692 | bayes_pls_golite062009 |
|
Region A: Residues: [216-334] |
1 11 21 31 41 51
| | | | | |
1 VKGDPASHAR KRQKGFHQYS KNGSVTARYV FCNYGSISDY KLLLKKNIDI EDKIHIVRSG 60
61 KILPGLKVKN AELYGASSVI IYTDPFDDGK VTEENGFLHY PYGPARNPSY IRRDSVNYF
|
|
Region B: Residues: [362-418] |
1 11 21 31 41 51
| | | | | |
1 VPRIPSVPMS ARDVQPILER LNGRGFQIGP GSNIKDFGSF TGPSSSIDKV HLHNELT
|
|
Region C: Residues: [653-811] |
1 11 21 31 41 51
| | | | | |
1 THVYLKKIYN WYIAWHSNLS SAFPQDDEVN SLAKRVLDLL KVATQEDSIQ FDQQNGILYK 60
61 ECREALPVWA FYKKIKSYIK LQRSNSKSKQ IDQLFITHRG LKDREWMKYS LLAPSKFEGS 120
121 VGEVLPGLHE GLADIDRNEV IQWLTILLSQ FSNVRYLLQ
|
| Detection Method: | |
| Confidence: | 359.9897 |
| Match: | 1de4C_ |
| Description: | Transferrin receptor ectodomain, C-terminal domain; Transferrin receptor ectodomain, apical domain; Transferrin receptor ectodomain, protease-like domain |
| Matching Structure (courtesy of the PDB): |
|
