| Protein: | CSN12 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 423 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CSN12.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..423] | [1..423] |
|
|
4.0E-94 | [23..420] | [40..393] |
|
|
7.0E-86 | [23..420] | [39..391] |
|
|
9.0E-85 | [27..415] | [95..418] |
|
Region A: Residues: [1-103] |
1 11 21 31 41 51
| | | | | |
1 MDVDIGCYFE EKRYDDKLLD FIRYDVKTPK KTKYILQRPT ATDEESVRLQ RFYQLGVDLK 60
61 LKYSKRRSLK KQGRIKNATE ELLRLANEQL KLFNRIVERE TNW
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.642 | a.24.3 | Cytochromes |
| View | Download | 0.604 | d.56.1 | GroEL-intermediate domain like |
| View | Download | 0.567 | a.7.1 | Spectrin repeat |
| View | Download | 0.541 | a.7.1 | Spectrin repeat |
| View | Download | 0.525 | a.7.7 | BAG domain |
| View | Download | 0.523 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.512 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.506 | a.74.1 | Cyclin-like |
| View | Download | 0.501 | a.118.8 | TPR-like |
| View | Download | 0.497 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.494 | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.492 | a.118.8 | TPR-like |
| View | Download | 0.479 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.476 | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.466 | a.24.12 | Outer surface protein C (OspC) |
| View | Download | 0.464 | a.47.2 | t-snare proteins |
| View | Download | 0.452 | a.7.1 | Spectrin repeat |
| View | Download | 0.450 | a.46.1 | Methionine synthase domain |
| View | Download | 0.449 | a.7.1 | Spectrin repeat |
| View | Download | 0.431 | a.39.1 | EF-hand |
| View | Download | 0.420 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.419 | c.23.4 | Succinyl-CoA synthetase domains |
| View | Download | 0.419 | a.7.1 | Spectrin repeat |
| View | Download | 0.419 | a.7.1 | Spectrin repeat |
| View | Download | 0.417 | c.59.1 | MurD-like peptide ligases, peptide-binding domain |
| View | Download | 0.415 | a.7.8 | GAT domain |
| View | Download | 0.415 | a.7.8 | GAT domain |
| View | Download | 0.410 | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.391 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.390 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.385 | a.24.3 | Cytochromes |
| View | Download | 0.376 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.370 | d.2.1 | Lysozyme-like |
| View | Download | 0.368 | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.365 | a.71.1 | Endoplasmic reticulum protein ERP29, C-domain |
| View | Download | 0.359 | a.60.10 | Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain |
| View | Download | 0.359 | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.358 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.352 | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.352 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.349 | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
| View | Download | 0.346 | c.36.1 | Thiamin diphosphate-binding fold (THDP-binding) |
| View | Download | 0.346 | c.55.3 | Ribonuclease H-like |
| View | Download | 0.342 | a.130.1 | Chorismate mutase II |
| View | Download | 0.341 | a.7.8 | GAT domain |
| View | Download | 0.341 | a.40.1 | Calponin-homology domain, CH-domain |
| View | Download | 0.338 | c.23.1 | CheY-like |
| View | Download | 0.338 | a.47.2 | t-snare proteins |
| View | Download | 0.332 | a.19.1 | Fertilization protein |
| View | Download | 0.330 | c.26.3 | UDP-glucose/GDP-mannose dehydrogenase C-terminal domain |
| View | Download | 0.330 | a.7.1 | Spectrin repeat |
| View | Download | 0.325 | f.31.1 | Photosystem I reaction center subunit XI, PsaL |
| View | Download | 0.317 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.314 | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.312 | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.312 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.311 | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.308 | c.23.1 | CheY-like |
| View | Download | 0.307 | c.20.1 | Initiation factor IF2/eIF5b, domain 3 |
| View | Download | 0.303 | a.47.2 | t-snare proteins |
| View | Download | 0.302 | d.68.3 | SirA-like |
| View | Download | 0.302 | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.301 | a.46.1 | Methionine synthase domain |
| View | Download | 0.295 | c.51.3 | B12-dependend dehydatases associated subunit |
| View | Download | 0.295 | a.26.1 | 4-helical cytokines |
| View | Download | 0.295 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.293 | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.292 | d.50.2 | Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain |
| View | Download | 0.289 | a.130.1 | Chorismate mutase II |
| View | Download | 0.289 | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.289 | d.232.1 | Mago nashi protein |
| View | Download | 0.288 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.288 | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.284 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.281 | d.95.2 | Homing endonucleases |
| View | Download | 0.279 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.279 | a.19.1 | Fertilization protein |
| View | Download | 0.278 | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.273 | a.60.10 | Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain |
| View | Download | 0.272 | a.130.1 | Chorismate mutase II |
| View | Download | 0.272 | a.46.1 | Methionine synthase domain |
| View | Download | 0.269 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.268 | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.265 | d.50.2 | Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain |
| View | Download | 0.264 | a.130.1 | Chorismate mutase II |
| View | Download | 0.262 | a.19.1 | Fertilization protein |
| View | Download | 0.258 | d.96.1 | Tetrahydrobiopterin biosynthesis enzymes-like |
| View | Download | 0.257 | c.102.1 | Cell-division inhibitor MinC, N-terminal domain |
| View | Download | 0.255 | d.68.6 | DNA-binding protein Sso10b (AlbA) |
| View | Download | 0.251 | d.68.7 | R3H domain |
| View | Download | 0.249 | a.156.1 | S13-like H2TH domain |
| View | Download | 0.249 | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.248 | a.19.1 | Fertilization protein |
| View | Download | 0.248 | a.26.1 | 4-helical cytokines |
| View | Download | 0.248 | a.47.2 | t-snare proteins |
| View | Download | 0.248 | a.24.3 | Cytochromes |
| View | Download | 0.245 | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.244 | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.244 | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.242 | c.49.1 | Pyruvate kinase, C-terminal domain |
| View | Download | 0.242 | a.90.1 | Transcription factor STAT-4 N-domain |
| View | Download | 0.240 | f.28.1 | Nonheme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| View | Download | 0.240 | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.238 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.238 | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.237 | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.236 | a.46.1 | Methionine synthase domain |
| View | Download | 0.235 | c.9.1 | Barstar (barnase inhibitor) |
| View | Download | 0.235 | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.235 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.233 | d.109.2 | C-terminal, gelsolin-like domain of Sec23/24 |
| View | Download | 0.233 | d.50.1 | dsRNA-binding domain-like |
| View | Download | 0.231 | b.36.1 | PDZ domain-like |
| View | Download | 0.230 | a.54.1 | Domain of early E2A DNA-binding protein, ADDBP |
| View | Download | 0.228 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.227 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.227 | c.23.12 | Formate/glycerate dehydrogenase catalytic domain-like |
| View | Download | 0.226 | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.225 | a.24.3 | Cytochromes |
| View | Download | 0.224 | d.19.1 | MHC antigen-recognition domain |
| View | Download | 0.224 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.223 | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.223 | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.222 | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.221 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.219 | a.19.1 | Fertilization protein |
| View | Download | 0.219 | a.39.1 | EF-hand |
| View | Download | 0.218 | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.217 | a.29.2 | Bromodomain |
| View | Download | 0.217 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.217 | a.46.1 | Methionine synthase domain |
| View | Download | 0.216 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.216 | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.214 | a.46.1 | Methionine synthase domain |
| View | Download | 0.213 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.208 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.207 | g.53.1 | TAZ domain |
| View | Download | 0.205 | a.24.3 | Cytochromes |
| View | Download | 0.204 | a.7.1 | Spectrin repeat |
| View | Download | 0.203 | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.203 | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
|
Region A: Residues: [104-423] |
1 11 21 31 41 51
| | | | | |
1 IIYPLWVMAK QLIRLANESS ELNKDSIEEC GRTIHRSFTI CLNDRNPRLN ENKKIGCYMF 60
61 ANLEFSIYHR LSNKDMIKNL VKVLESRVNA RDIPPLNKSL AMEHKSQVVL YNYYLGQYYG 120
121 CLENDHERGF FHLNEALLQC PMLYVESTGK FVLQGQMEKI MILLVPLALL TKRLYPHWDH 180
181 PVIAGVITRS KRLSQVYPTL VRSVISGNLS LYEATAASHE RFFLSQGLHV VITLLREVVF 240
241 TRLVQRCWQW GNDRKSIMPL KILLATKQHD SSANEDEEEQ LDALECRLAS AIASGLLRAY 300
301 LSHSNRCIVF SKKEPFPHSK
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [356-423] |
1 11 21 31 41 51
| | | | | |
1 DRKSIMPLKI LLATKQHDSS ANEDEEEQLD ALECRLASAI ASGLLRAYLS HSNRCIVFSK 60
61 KEPFPHSK
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| Detection Method: | |
| Confidence: | 1.96 |
| Match: | 1ufmA |
| Description: | Solution structure of the PCI domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 4.13436454849845 | bayes_pls_golite062009 |
| DNA binding | 3.77959139017704 | bayes_pls_golite062009 |
| nucleic acid binding | 3.61852605343839 | bayes_pls_golite062009 |
| binding | 3.37660003833383 | bayes_pls_golite062009 |
| transcription factor activity | 3.18366984273735 | bayes_pls_golite062009 |
| transcription repressor activity | 2.13838000453063 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.67826024217505 | bayes_pls_golite062009 |
| transcription activator activity | 1.36268391567196 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 1.01831614309793 | bayes_pls_golite062009 |
| protein binding | 0.726445167461826 | bayes_pls_golite062009 |
| RNA binding | 0.309381817803407 | bayes_pls_golite062009 |
| transcription factor binding | 0.0307736199991748 | bayes_pls_golite062009 |
