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View Structure Prediction Details

Protein: RAV1
Organism: Saccharomyces cerevisiae
Length: 1357 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RAV1.

Description E-value Query
Range
Subject
Range
gi|1197061 - gi|1197061|gb|AAA88735.1| ORF; putative [Saccharomyces cerevisiae]
0.0 [1..1016] [1..1016]
gi|16944675 - gi|16944675|emb|CAB99185.2| conserved hypothetical protein [Neurospora crassa]
0.0 [28..1211] [39..1290]
DMXL2 - Dmx-like 2
0.0 [790..1202] [1471..1915]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [790..1202] [1768..2259]
rav1 - RAVE complex subunit Rav1
RAV1_SCHPO - Regulator of V-ATPase in vacuolar membrane protein 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC...
0.0 [1..1197] [1..1238]

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Predicted Domain #1
Region A:
Residues: [1-98]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLNFLPGRP NATPQTACQA TWQNHTIFAY CSGNNLIILT NKFTRLQTIY TQSDCTAVDI  60
   61 NSQNGFIALS FHNRVLIYKP IHQIMQNPKW TQCCQLFH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.045757
Match: 1gg2B_
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.79788997337153 bayes_pls_golite062009
GTPase activity 1.66665311782591 bayes_pls_golite062009
transporter activity 1.21549336905926 bayes_pls_golite062009
protein binding 1.11897341394404 bayes_pls_golite062009
substrate-specific transporter activity 0.734793983890004 bayes_pls_golite062009
hydrolase activity 0.28424525033024 bayes_pls_golite062009
G-protein-coupled receptor binding 0.203853592066275 bayes_pls_golite062009
0.13986688456512 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [99-498]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDTPVNCLRW SSDNELAIGS DFLSFWKIKD NFGVYQPILQ WNQKQPKPVY NVIISQDSQL  60
   61 IVSIGKYDCN AKLWKRVSIV GEQAIFNLTM LPHPKPITAM RWKKEPDQVS KNNTASHALY 120
  121 TLCEDKVLRI WSCFEMEKNH TVQIWGEVPL SPTQKFCVII DNWIIRQTLS VKDSEIFDIS 180
  181 DSDIVILGSM TGEMEVLALN NLSQDPPKPM TKKTISHKKV KKATMLNDTR YLYLPEIQPY 240
  241 DNVKGKLSFL VHDLQGVIRH LLIDILQLIN NKTEDLSAAL EHKFTGHNKS VQKLVRSSDG 300
  301 EALLTTSRFS ENGVWYPQKL NHGVSLRLQN TIQTESPIKF AVVHELGKQV ICLLENGALQ 360
  361 AWECPTNRKE DSEQKQSYLR VETRLKEEKK IHPIVMLNTP 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.69897
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [499-827]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPKHSHERHF TALIFSDGSI KAFEVSLTRG IFEVKSDSLD IDGDDIYKIS IIDPVHQTFV  60
   61 SNRPLISLIT KKGLTRTYKA IVNYNDRHVQ WIKACEINTG IMNCTCIRGS STGKLCIVNS 120
  121 TGKVMSLWDL NRGVLEYEET FHNPIEDIDW TSTEYGQSIV SIGFTGYALL YTQLRYDYTN 180
  181 NTPSYLPIEK IDITAHTAHN IGDSVWMKNG TFVVASGNQF YIKDKSLDLT DPFTYQSIGS 240
  241 RKILSNDILH LSSVLNGPLP VYHPQFLIQA IYANKLQLVK ELLLRLFLAL RKLDFESQDV 300
  301 SNLDSNLGMD PLKYFIAKDR DYPVESFPD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [828-841]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PYPCFNKTVS LALT

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [853-989]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRHQQITLIT VIEAVDEVTK NENIVDYNGV RFLLGVKLFL SHKNIQKSIL MRDVSWALHS  60
   61 DNKEILLSSI DRHITSWNRA REYRIAYWIK EQDLVKKFED IAKYEFSKDD KRDPSRCAIF 120
  121 YLALKKKQIL LSLWKMA

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.54
Match: 1n1bA
Description: (+)-bornyl diphosphate synthase
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [842-852]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQLTKTTLPY L

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [990-1113]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGHPEQQKMV RFISNDFTVP RWRTAALKNA FVLLSKHRYM DAAVFFLLTD SLKDCVNVLC  60
   61 KQVHDMDLAI GVCRVYEGDN GPVLGELLTA QMLPETIKEN DRWKASFIYW KLRKQEVAIK 120
  121 ALLT

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.54
Match: 1n1bA
Description: (+)-bornyl diphosphate synthase
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [1114-1357]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APIDLENNSS IVDKEVCVNR SFLVEDPALL YLYNHLRNRN LKYFIGSLNV EAKIECTLIL  60
   61 RVTDILCRMG CNYLAVSLVK NWKFIERNSI PVQKLLKSPT KDRAYSAIGA MASEPISTAR 120
  121 MRPSLFDKFG SPSASDIESP NPKLPNSLLD DFLQPPPNST SSNSLAQSSS SAPRSILDEF 180
  181 VSPSYSQHKE NLTPKAPNDS VGETDNSENR KDKLSKDILD DLSSQKPQKP KKSAITKNLL 240
  241 DDFV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1199-1357]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ERNSIPVQKL LKSPTKDRAY SAIGAMASEP ISTARMRPSL FDKFGSPSAS DIESPNPKLP  60
   61 NSLLDDFLQP PPNSTSSNSL AQSSSSAPRS ILDEFVSPSY SQHKENLTPK APNDSVGETD 120
  121 NSENRKDKLS KDILDDLSSQ KPQKPKKSAI TKNLLDDFV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle