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View Structure Prediction Details

Protein: RFA3
Organism: Saccharomyces cerevisiae
Length: 122 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RFA3.

Description E-value Query
Range
Subject
Range
RFA3 - Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded D...
RFA3_YEAST - Replication factor A protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RFA3 PE=1...
8.0E-69 [1..122] [1..122]

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Predicted Domain #1
Region A:
Residues: [1-122]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASETPRVDP TEISNVNAPV FRIIAQIKSQ PTESQLILQS PTISSKNGSE VEMITLNNIR  60
   61 VSMNKTFEID SWYEFVCRNN DDGELGFLIL DAVLCKFKEN EDLSLNGVVA LQRLCKKYPE 120
  121 IY

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Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
telomeric DNA binding 6.80354805962079 bayes_pls_golite062009
single-stranded telomeric DNA binding 5.68297908219419 bayes_pls_golite062009
telomerase inhibitor activity 5.1433503909639 bayes_pls_golite062009
structure-specific DNA binding 3.21942642139833 bayes_pls_golite062009
single-stranded DNA binding 3.2177041772475 bayes_pls_golite062009
nucleic acid binding 3.06958664528424 bayes_pls_golite062009
binding 2.55343783977289 bayes_pls_golite062009
DNA binding 2.39520356118846 bayes_pls_golite062009
structural constituent of ribosome 2.05553707774342 bayes_pls_golite062009
structural molecule activity 1.91392288234828 bayes_pls_golite062009
DNA helicase activity 1.03434608237928 bayes_pls_golite062009
transcription regulator activity 0.786603442061911 bayes_pls_golite062009
DNA-dependent ATPase activity 0.633347054314125 bayes_pls_golite062009
translation regulator activity 0.370723767971907 bayes_pls_golite062009
nuclease activity 0.344602655860014 bayes_pls_golite062009
ribonuclease activity 0.327087435405429 bayes_pls_golite062009
double-stranded DNA binding 0.326586310136168 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.322367891458082 bayes_pls_golite062009
nucleotidyltransferase activity 0.285831998808043 bayes_pls_golite062009
DEAD/H-box RNA helicase binding 0.234313553803999 bayes_pls_golite062009
four-way junction helicase activity 0.149878585899218 bayes_pls_golite062009
exonuclease activity 0.123437412322173 bayes_pls_golite062009
sequence-specific DNA binding 0.112654475341878 bayes_pls_golite062009
protein binding 0.0856707433885143 bayes_pls_golite062009
transcription factor activity 0.0739391344707232 bayes_pls_golite062009
translation initiation factor activity 0.0214826254708589 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle