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View Structure Prediction Details

Protein: GZF3
Organism: Saccharomyces cerevisiae
Length: 551 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GZF3.

Description E-value Query
Range
Subject
Range
GZF3_YEAST - Protein GZF3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GZF3 PE=1 SV=1
GZF3 - GATA zinc finger protein and Dal80p homolog that negatively regulates nitrogen catabolic gene expres...
0.0 [1..551] [1..551]
TCNA_TRYCR - Sialidase OS=Trypanosoma cruzi GN=TCNA PE=2 SV=1
3.0E-45 [6..419] [625..1037]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-39 [74..180] [1..108]
gi|8648977 - gi|8648977|emb|CAB94842.1| GATA-4 zinc-finger transcription factor [Oryctolagus cuniculus]
4.0E-39 [73..186] [2..116]
gi|3702858 - gi|3702858|gb|AAC62961.1| GATA transcription factor [Strongylocentrotus purpuratus]
1.0E-37 [76..191] [2..119]
gi|18032000 - gi|18032000|gb|AAL32068.1| pannier-like protein [Calliphora vicina]
6.0E-35 [3..341] [49..399]
gi|119112909, gi... - ref|XP_307949.1| ENSANGP00000006261 [Anopheles gambiae], gi|119112909|ref|XP_307949.3| AGAP002235-P...
gi|15420800 - gi|15420800|gb|AAK97462.1|AF395080_1 zinc finger transcription factor pannier [Anopheles gambiae]
2.0E-33 [2..330] [44..369]
gi|7381420 - gi|7381420|gb|AAF61481.1|AF184154_1 zinc finger DNA binding protein pannier [Ceratitis capitata]
3.0E-33 [3..189] [42..223]
gi|603164 - gi|603164|gb|AAA67886.1| BmGATA beta isoform 1
6.0E-33 [63..205] [59..200]

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Predicted Domain #1
Region A:
Residues: [1-123]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASQATTLRG YNIRKRDNVF EPKSSENLNS LNQSEEEGHI GRWPPLGYEA VSAEQKSAVQ  60
   61 LRESQAGASI SNNMNFKAND KSFSTSTAGR MSPDTNSLHH ILPKNQVKNN GQTMDANCNN 120
  121 NVS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.362 a.24.17 Group V grass pollen allergen
View Download 0.305 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.362 a.24.17 Group V grass pollen allergen
View Download 0.305 a.71.1 Endoplasmic reticulum protein ERP29, C-domain

Predicted Domain #2
Region A:
Residues: [124-192]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDANVPVCKN CLTSTTPLWR RDEHGAMLCN ACGLFLKLHG KPRPISLKTD VIKSRNRKSN  60
   61 TNHAHNLDN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 173.68867
Match: 4gatA_
Description: Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.00967542385368 bayes_pls_golite062009
DNA binding 3.60745514727532 bayes_pls_golite062009
nucleic acid binding 3.47256374293954 bayes_pls_golite062009
binding 2.96409924710655 bayes_pls_golite062009
transcription factor activity 2.90769972671972 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.40923942043513 bayes_pls_golite062009
transcription repressor activity 1.88834375049208 bayes_pls_golite062009
sequence-specific DNA binding 1.62841402245495 bayes_pls_golite062009
transcription activator activity 1.62405765585032 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 1.49515149729803 bayes_pls_golite062009
protein binding 1.39455913713025 bayes_pls_golite062009
transcription factor binding 1.38523780690867 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.26452462867497 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.68943696300126 bayes_pls_golite062009
transcription cofactor activity 0.58115018700114 bayes_pls_golite062009
catalytic activity 0.101795606736461 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [193-478]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FRNQTLIAEL KGDCNIESSG RKANRVTSED KKKKSSQLLM GTSSTAKISK KPKTESKERS  60
   61 DSHLSATKLE VLMSGDCSRP NLKPKLPKQD TAIYQEKLLT FPSYTDVKEY SNSAHQSAFI 120
  121 KERSQFNAAS FPLNASHSVT SKTGADSPQL PHLSMLLGSL SSTSISNNGS EIVSNCNNGI 180
  181 ASTAATLAPT SSRTTDSNPS EVPNQIRSTM SSPDIISAKR NDPAPLSFHM ASINDMLETR 240
  241 DRAISNVKTE TTPPHFIPFL QSSKAPCISK ANSQSISNSV SSSDVS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [479-551]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRKFENHPAK DLGDQLSTKL HKEEEIIKLK TRINELELVT DLYRRHINEL DGKCRALEER  60
   61 LQRTVKQEGN KGG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.716 0.061 regulation of nitrogen utilization a.77.1 DEATH domain
View Download 0.712 0.053 regulation of nitrogen utilization a.60.1 SAM/Pointed domain
View Download 0.807 0.028 regulation of nitrogen utilization a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.581 0.003 regulation of nitrogen utilization a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.697 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.549 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.530 N/A N/A a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.516 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.502 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.499 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.498 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.487 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.483 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.478 N/A N/A a.77.1 DEATH domain
View Download 0.471 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.468 N/A N/A a.118.1 ARM repeat
View Download 0.464 N/A N/A a.60.11 Hypothetical protein YjbJ
View Download 0.455 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.450 N/A N/A a.118.11 Cytochrome c oxidase subunit E
View Download 0.449 N/A N/A a.64.1 Saposin
View Download 0.448 N/A N/A a.64.2 Bacteriocin AS-48
View Download 0.434 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.433 N/A N/A a.159.2 FF domain
View Download 0.428 N/A N/A a.77.1 DEATH domain
View Download 0.422 N/A N/A a.65.1 Annexin
View Download 0.407 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.407 N/A N/A a.64.2 Bacteriocin AS-48
View Download 0.398 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.396 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.384 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.382 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.371 N/A N/A a.4.1 Homeodomain-like
View Download 0.369 N/A N/A a.4.1 Homeodomain-like
View Download 0.368 N/A N/A d.58.49 YajQ-like
View Download 0.368 N/A N/A a.23.5 Hemolysin expression modulating protein HHA
View Download 0.365 N/A N/A a.65.1 Annexin
View Download 0.358 N/A N/A c.9.1 Barstar (barnase inhibitor)
View Download 0.356 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.350 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.346 N/A N/A a.65.1 Annexin
View Download 0.343 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.343 N/A N/A d.120.1 Cytochrome b5
View Download 0.341 N/A N/A a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.340 N/A N/A a.50.1 Anaphylotoxins (complement system)
View Download 0.336 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.334 N/A N/A a.61.1 Retroviral matrix proteins
View Download 0.333 N/A N/A a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.331 N/A N/A a.23.5 Hemolysin expression modulating protein HHA
View Download 0.331 N/A N/A a.118.1 ARM repeat
View Download 0.328 N/A N/A d.68.3 SirA-like
View Download 0.327 N/A N/A a.64.1 Saposin
View Download 0.321 N/A N/A a.64.2 Bacteriocin AS-48
View Download 0.321 N/A N/A a.65.1 Annexin
View Download 0.316 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.315 N/A N/A d.50.3 PI-Pfui intein middle domain
View Download 0.314 N/A N/A a.4.1 Homeodomain-like
View Download 0.311 N/A N/A a.64.2 Bacteriocin AS-48
View Download 0.310 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.309 N/A N/A a.118.11 Cytochrome c oxidase subunit E
View Download 0.309 N/A N/A a.112.1 Description not found.
View Download 0.308 N/A N/A a.4.1 Homeodomain-like
View Download 0.307 N/A N/A a.16.1 S15/NS1 RNA-binding domain
View Download 0.304 N/A N/A a.4.7 Ribosomal protein L11, C-terminal domain
View Download 0.301 N/A N/A a.4.8 Ribosomal protein S18
View Download 0.301 N/A N/A a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.298 N/A N/A a.50.1 Anaphylotoxins (complement system)
View Download 0.297 N/A N/A a.3.1 Cytochrome c
View Download 0.296 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.294 N/A N/A a.153.1 Nuclear receptor coactivator interlocking domain
View Download 0.294 N/A N/A c.10.2 L domain-like
View Download 0.292 N/A N/A d.195.1 YopH tyrosine phosphatase N-terminal domain
View Download 0.291 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.290 N/A N/A a.4.1 Homeodomain-like
View Download 0.290 N/A N/A a.60.11 Hypothetical protein YjbJ
View Download 0.286 N/A N/A a.77.1 DEATH domain
View Download 0.284 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.283 N/A N/A a.39.1 EF-hand
View Download 0.278 N/A N/A a.60.11 Hypothetical protein YjbJ
View Download 0.277 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.275 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.274 N/A N/A a.85.1 Hemocyanin, N-terminal domain
View Download 0.272 N/A N/A a.118.11 Cytochrome c oxidase subunit E
View Download 0.271 N/A N/A a.65.1 Annexin
View Download 0.268 N/A N/A a.64.1 Saposin
View Download 0.266 N/A N/A d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.264 N/A N/A a.3.1 Cytochrome c
View Download 0.257 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.257 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.256 N/A N/A a.3.1 Cytochrome c
View Download 0.254 N/A N/A a.60.11 Hypothetical protein YjbJ
View Download 0.254 N/A N/A a.60.2 RuvA domain 2-like
View Download 0.252 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.252 N/A N/A a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.251 N/A N/A a.4.8 Ribosomal protein S18
View Download 0.251 N/A N/A d.58.17 Metal-binding domain
View Download 0.249 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.247 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.246 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.243 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.242 N/A N/A a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.240 N/A N/A c.9.1 Barstar (barnase inhibitor)
View Download 0.239 N/A N/A a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.238 N/A N/A a.6.1 Putative DNA-binding domain
View Download 0.235 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.234 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.233 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.233 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.232 N/A N/A a.17.1 p8-MTCP1
View Download 0.231 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.231 N/A N/A a.159.1 Protein serine/threonine phosphatase 2C, C-terminal domain
View Download 0.230 N/A N/A a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.226 N/A N/A a.46.1 Methionine synthase domain
View Download 0.225 N/A N/A a.156.1 S13-like H2TH domain
View Download 0.223 N/A N/A a.29.2 Bromodomain
View Download 0.223 N/A N/A a.77.1 DEATH domain
View Download 0.223 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.223 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.222 N/A N/A a.61.1 Retroviral matrix proteins
View Download 0.222 N/A N/A a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.219 N/A N/A a.144.1 PABC (PABP) domain
View Download 0.218 N/A N/A a.3.1 Cytochrome c
View Download 0.217 N/A N/A a.29.2 Bromodomain
View Download 0.214 N/A N/A a.28.2 Colicin E immunity proteins
View Download 0.214 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.213 N/A N/A a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.212 N/A N/A a.142.1 PTS-regulatory domain, PRD
View Download 0.210 N/A N/A a.30.1 ROP protein
View Download 0.209 N/A N/A a.157.1 Skp1 dimerisation domain-like
View Download 0.209 N/A N/A a.118.11 Cytochrome c oxidase subunit E
View Download 0.208 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.208 N/A N/A a.20.1 PGBD-like
View Download 0.207 N/A N/A a.46.1 Methionine synthase domain
View Download 0.205 N/A N/A a.46.1 Methionine synthase domain
View Download 0.204 N/A N/A d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.204 N/A N/A a.1.1 Globin-like
View Download 0.203 N/A N/A a.20.1 PGBD-like
View Download 0.202 N/A N/A a.140.1 LEM domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle