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View Structure Prediction Details

Protein: UTP10
Organism: Saccharomyces cerevisiae
Length: 1769 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UTP10.

Description E-value Query
Range		 Subject
Range
HEAT1_MACFA - HEAT repeat-containing protein 1 (Fragment) OS=Macaca fascicularis GN=HEATR1 PE=2 SV=2
 0.0 [831..1767] [1..957]
UTP10_YEAST - U3 small nucleolar RNA-associated protein 10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...
UTP10 - Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is ...
 0.0 [1..1769] [1..1769]
HEATR1 - HEAT repeat containing 1
gi|168278405 - gi|168278405|dbj|BAG11082.1| HEAT repeat-containing protein 1 [synthetic construct]
 0.0 [713..1767] [1067..2143]
UTP10_SCHPO - U3 small nucleolar RNA-associated protein 10 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) ...
utp10 - U3 snoRNP-associated protein Utp10
 0.0 [2..1768] [3..1648]
gi|17862936 - gi|17862936|gb|AAL39945.1| SD03723p [Drosophila melanogaster]
 0.0 [748..1768] [665..1690]
toe-1 - status:Partially_confirmed UniProt:Q23495 protein_id:AAA83581.1
 0.0 [824..1764] [606..1643]
gi|18043996 - gi|18043996|gb|AAH19693.1| Heatr1 protein [Mus musculus]
 0.0 [1436..1767] [9..348]

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Predicted Domain #1
Region A:
Residues: [1-186] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLSDQLAQ VASNNATVAL DRKRRQKLHS ASLIYNSKTA ATQDYDFIFE NASKALEELS  60
   61 QIEPKFAIFS RTLFSESSIS LDRNVQTKEE IKDLDNAINA YLLLASSKWY LAPTLHATEW 120
  121 LVRRFQIHVK NTEMLLLSTL NYYQTPVFKR ILSIIKLPPL FNCLSNFVRS EKPPTALTMI 180
  181 KLFNDM

[Run NCBI BLAST on this sequence.]

Detection Method: Pcons
Confidence: 2.7
Match: 1b3uA
Description: Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [187-253] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFLKLYTSYL DQCIKHNATY TNQLLFTTCC FINVVAFNSN NDEKLNQLVP ILLEISAKLL  60
   61 ASKSKDC

[Run NCBI BLAST on this sequence.]

Detection Method: Pcons
Confidence: 2.7
Match: 1b3uA
Description: Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [254-401] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QIAAHTILVV FATALPLKKT IILAAMETIL SNLDAKEAKH SALLTICKLF QTLKGQGNVD  60
   61 QLPSKIFKLF DSKFDTVSIL TFLDKEDKPV CDKFITSYTR SIARYDRSKL NIILSLLKKI 120
  121 RLERYEVRLI ITDLIYLSEI LEDKSQLV

[Run NCBI BLAST on this sequence.]

Detection Method: Pcons
Confidence: 2.7
Match: 1b3uA
Description: Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [402-606] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELFEYFISIN EDLVLKCLKS LGLTGELFEI RLTTSLFTNA DVNTDIVKQL SDPVETTKKD  60
   61 TASFQTFLDK HSELINTTNV SMLTETGERY KKVLSLFTEA IGKGYKASSF LTSFFTTLES 120
  121 RITFLLRVTI SPAAPTALKL ISLNNIAKYI NSIEKEVNIF TLVPCLICAL RDASIKVRTG 180
  181 VKKILSLIAK RPSTKHYFLS DKLYG

[Run NCBI BLAST on this sequence.]

Detection Method: Pcons
Confidence: 2.7
Match: 1b3uA
Description: Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [607-663] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENVTIPMLNP KDSEAWLSGF LNEYVTENYD ISRILTPKRN EKVFLMFWAN QALLIPS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
RNA binding 3.36069436734718 bayes_pls_golite062009
binding 2.96084803796407 bayes_pls_golite062009
nucleic acid binding 2.69616509670156 bayes_pls_golite062009
protein binding 2.66176697577398 bayes_pls_golite062009
transcription regulator activity 2.19067997822967 bayes_pls_golite062009
DNA binding 1.96172460362671 bayes_pls_golite062009
structural molecule activity 1.49650156618775 bayes_pls_golite062009
transcription activator activity 1.47146260606784 bayes_pls_golite062009
mRNA binding 1.35186555044783 bayes_pls_golite062009
transcription factor activity 1.21493607378314 bayes_pls_golite062009
transcription factor binding 8.79739237675814E-4 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [664-818] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PYAKTVLLDN LNKSPTYASS YSSLFEEFIS HYLENRSSWE KSCIANKTNF EHFERSLVNL  60
   61 VSPKEKQSFM IDFVLSALNS DYEQLANIAA ERLISIFASL NNAQKLKIVQ NIVDSSSNVE 120
  121 SSYDTVGVLQ SLPLDSDIFV SILNQNSISN EMDQT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [819-1769] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFSKRRRRRS STSKNAFLKE EVSQLAELHL RKLTIILEAL DKVRNVGSEK LLFTLLSLLS  60
   61 DLETLDQDGG LPVLYAQETL ISCTLNTITY LKEHGCTELT NVRADILVSA IRNSASPQVQ 120
  121 NKLLLVIGSL ATLSSEVILH SVMPIFTFMG AHSIRQDDEF TTKVVERTIL TVVPALIKNS 180
  181 KGNEKEEMEF LLLSFTTALQ HVPRHRRVKL FSTLIKTLDP VKALGSFLFL IAQQYSSALV 240
  241 NFKIGEARIL IEFIKALLVD LHVNEELSGL NDLLDIIKLL TSSKSSSEKK KSLESRVLFS 300
  301 NGVLNFSESE FLTFMNNTFE FINKITEETD QDYYDVRRNL RLKVYSVLLD ETSDKKLIRN 360
  361 IREEFGTLLE GVLFFINSVE LTFSCITSQE NEEASDSETS LSDHTTEIKE ILFKVLGNVL 420
  421 QILPVDEFVN AVLPLLSTST NEDIRYHLTL VIGSKFELEG SEAIPIVNNV MKVLLDRMPL 480
  481 ESKSVVISQV ILNTMTALVS KYGKKLEGSI LTQALTLATE KVSSDMTEVK ISSLALITNC 540
  541 VQVLGVKSIA FYPKIVPPSI KLFDASLADS SNPLKEQLQV AILLLFAGLI KRIPSFLMSN 600
  601 ILDVLHVIYF SREVDSSIRL SVISLIIENI DLKEVLKVLF RIWSTEIATS NDTVAVSLFL 660
  661 STLESTVENI DKKSATSQSP IFFKLLLSLF EFRSISSFDN NTISRIEASV HEISNSYVLK 720
  721 MNDKVFRPLF VILVRWAFDG EGVTNAGITE TERLLAFFKF FNKLQENLRG IITSYFTYLL 780
  781 EPVDMLLKRF ISKDMENVNL RRLVINSLTS SLKFDRDEYW KSTSRFELIS VSLVNQLSNI 840
  841 ENSIGKYLVK AIGALASNNS GVDEHNQILN KLIVEHMKAS CSSNEKLWAI RAMKLIYSKI 900
  901 GESWLVLLPQ LVPVIAELLE DDDEEIEREV RTGLVKVVEN VLGEPFDRYL D

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle