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View Structure Prediction Details

Protein: YAP1801
Organism: Saccharomyces cerevisiae
Length: 637 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YAP1801.

Description E-value Query
Range
Subject
Range
AP18A_YEAST - Clathrin coat assembly protein AP180A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YA...
YAP1801 - Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1802p, member...
0.0 [1..637] [1..637]
gi|15079267, gi|... - gi|74189804|dbj|BAE36872.1| unnamed protein product [Mus musculus], gi|15079267|gb|AAH11470.1| Pical...
0.0 [2..627] [20..651]
PICAL_RAT - Phosphatidylinositol-binding clathrin assembly protein OS=Rattus norvegicus GN=Picalm PE=1 SV=1
0.0 [2..627] [20..636]
CAP9_ARATH - Putative clathrin assembly protein At1g14910 OS=Arabidopsis thaliana GN=At1g14910 PE=2 SV=2
0.0 [3..604] [31..611]
unc-11 - status:Confirmed UniProt:Q9XZI6 protein_id:AAK68212.1
0.0 [2..512] [35..539]

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Predicted Domain #1
Region A:
Residues: [1-122]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTYFKLVKG ATKIKSAPPK QKYLDPILLG TSNEEDFYEI VKGLDSRIND TAWTIVYKSL  60
   61 LVVHLMIREG SKDVALRYYS RNLEFFDIEN IRGSNGSASG DMRALDRYDN YLKVRCREFG 120
  121 KI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [167-192]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALIKNKYTQY DLSNELIIFG FKLLIQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 298.519517
Match: 1hf8A_
Description: Clathrin assembly lymphoid myeloid leukaemia protein, Calm
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
clathrin binding 2.70535896247543 bayes_pls_golite062009
binding 2.34501465852339 bayes_pls_golite062009
protein binding 1.7891964555817 bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate binding 1.20269437433936 bayes_pls_golite062009
phosphoinositide binding 0.87586037360588 bayes_pls_golite062009
phospholipid binding 0.84481265656013 bayes_pls_golite062009
lipid binding 0.176990783274449 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [123-166]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKDYVRDGYR TLKLNSGNYG SSRNKQHSIN IALDHVESLE VQIQ

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [193-271]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLLALYNALN EGIITLLESF FELSHHNAER TLDLYKTFVD LTEHVVRYLK SGKTAGLKIP  60
   61 VIKHITTKLV RSLEEHLIE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 298.519517
Match: 1hf8A_
Description: Clathrin assembly lymphoid myeloid leukaemia protein, Calm
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [272-338]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDKTHNTFVP VDSSQGSAGA VVAKSTAQER LEQIREQKRI LEAQLKNEQV AISPALTTVT  60
   61 AAQSYNP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.332 0.921 clathrin binding a.39.1 EF-hand
View Download 0.306 0.921 clathrin binding a.4.1 Homeodomain-like
View Download 0.297 0.921 clathrin binding a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.429 0.921 clathrin binding a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.322 0.921 clathrin binding a.5.6 Hypothetical protein MTH1615
View Download 0.264 0.921 clathrin binding a.60.12 DNA polymerase beta-like, second domain
View Download 0.246 0.921 clathrin binding a.144.1 PABC (PABP) domain
View Download 0.239 0.921 clathrin binding a.112.1 Description not found.
View Download 0.237 0.921 clathrin binding a.32.1 Transcription factor IIA (TFIIA), alpha-helical domain
View Download 0.237 0.921 clathrin binding a.2.3 Chaperone J-domain
View Download 0.224 0.921 clathrin binding g.53.1 TAZ domain
View Download 0.213 0.921 clathrin binding d.15.1 Ubiquitin-like
View Download 0.210 0.921 clathrin binding a.16.1 S15/NS1 RNA-binding domain
View Download 0.207 0.921 clathrin binding d.58.11 EF-G/eEF-2 domains III and V
View Download 0.206 0.921 clathrin binding a.112.1 Description not found.

Predicted Domain #4
Region A:
Residues: [339-637]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FGTDSSMHTN IPMAVANQTQ QIANNPFVSQ TQPQVMNTPT AHTEPANLNV PEYAAVQHTV  60
   61 NFNPVQDAGV SAQQTGYYSI NNHLTPTFTG AGFGGYSVSQ DTTAASNQQV SHSQTGSNNP 120
  121 FALHNAATIA TGNPAHENVL NNPFSRPNFD EQNTNMPLQQ QIISNPFQNQ TYNQQQFQQQ 180
  181 KMPLSSINSV MTTPTSMQGS MNIPQRFDKM EFQAHYTQNH LQQQQQQQQQ QQQQQQQQPQ 240
  241 QGYYVPATAG ANPVTNITGT VQPQNFPFYP QQQPQPEQSQ TQQPVLGNQY ANNLNLIDM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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Created and Maintained by: Michael Riffle