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Protein Overview: AP18A_YEAST

General Information:
Name(s) found: AP18A_YEAST [Swiss-Prot]
Description(s) found:
  • Clathrin coat assembly protein AP180A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YAP1801 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 637 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTYFKLVKG ATKIKSAPPK QKYLDPILLG TSNEEDFYEI VKGLDSRIND TAWTIVYKSL  60
   61 LVVHLMIREG SKDVALRYYS RNLEFFDIEN IRGSNGSASG DMRALDRYDN YLKVRCREFG 120
  121 KIKKDYVRDG YRTLKLNSGN YGSSRNKQHS INIALDHVES LEVQIQALIK NKYTQYDLSN 180
  181 ELIIFGFKLL IQDLLALYNA LNEGIITLLE SFFELSHHNA ERTLDLYKTF VDLTEHVVRY 240
  241 LKSGKTAGLK IPVIKHITTK LVRSLEEHLI EDDKTHNTFV PVDSSQGSAG AVVAKSTAQE 300
  301 RLEQIREQKR ILEAQLKNEQ VAISPALTTV TAAQSYNPFG TDSSMHTNIP MAVANQTQQI 360
  361 ANNPFVSQTQ PQVMNTPTAH TEPANLNVPE YAAVQHTVNF NPVQDAGVSA QQTGYYSINN 420
  421 HLTPTFTGAG FGGYSVSQDT TAASNQQVSH SQTGSNNPFA LHNAATIATG NPAHENVLNN 480
  481 PFSRPNFDEQ NTNMPLQQQI ISNPFQNQTY NQQQFQQQKM PLSSINSVMT TPTSMQGSMN 540
  541 IPQRFDKMEF QAHYTQNHLQ QQQQQQQQQQ QQQQQQPQQG YYVPATAGAN PVTNITGTVQ 600
  601 PQNFPFYPQQ QPQPEQSQTQ QPVLGNQYAN NLNLIDM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..122]
    [167..192]    		 PSI-BLAST 298.519517 Clathrin assembly lymphoid myeloid leukaemia protein, Calm
    2 View Details [123..166]
    [193..271]    		 PSI-BLAST 298.519517 Clathrin assembly lymphoid myeloid leukaemia protein, Calm
    3 View Details [272..338] deduced N/A Confident ab initio structure predictions are available.
    4 View Details [339..637] MSA 43.388997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • clathrin binding
    		•  2.70535896247543 bayes_pls_golite062009
  • binding
    		•  2.34501465852339 bayes_pls_golite062009
  • protein binding
    		•  1.7891964555817 bayes_pls_golite062009
  • phosphatidylinositol-4,5-bisphosphate binding
    		•  1.20269437433936 bayes_pls_golite062009
  • phosphoinositide binding
    		•  0.87586037360588 bayes_pls_golite062009
  • phospholipid binding
    		•  0.84481265656013 bayes_pls_golite062009
  • lipid binding
    		•  0.176990783274449 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle