






| Protein: | HSE1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 452 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HSE1.
| Description | E-value | Query Range |
Subject Range |
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9.0E-89 | [1..452] | [1..452] |
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1.0E-72 | [4..440] | [5..460] |
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3.0E-70 | [4..440] | [5..460] |
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2.0E-69 | [4..439] | [5..457] |
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3.0E-64 | [2..420] | [3..424] |
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4.0E-56 | [5..374] | [6..367] |
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2.0E-51 | [5..440] | [7..499] |
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Region A: Residues: [1-78] |
1 11 21 31 41 51
| | | | | |
1 MSSSAIKIRN ALLKATDPKL RSDNWQYILD VCDLVKEDPE DNGQEVMSLI EKRLEQQDAN 60
61 VILRTLSLTV SLAENCGS
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| Detection Method: | |
| Confidence: | 132.594777 |
| Match: | 1elkA_ |
| Description: | Tom1 protein |
Matching Structure (courtesy of the PDB):![]() |
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Region A: Residues: [79-146] |
1 11 21 31 41 51
| | | | | |
1 RLRQEISSKN FTSLLYALIE SHSVHITLKK AVTDVVKQLS DSFKDDPSLR AMGDLYDKIK 60
61 RKAPYLVQ
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| Detection Method: | |
| Confidence: | 132.594777 |
| Match: | 1elkA_ |
| Description: | Tom1 protein |
Matching Structure (courtesy of the PDB):![]() |
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Region A: Residues: [147-207] |
1 11 21 31 41 51
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1 PNVPEKHNMS TQADNSDDEE LQKALKMSLF EYEKQKKLQE QEKESAEVLP QQQQQHQQQN 60
61 Q
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Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| binding | 2.47621789723131 | bayes_pls_golite062009 |
| protein binding | 2.10925438883926 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.29637592432055 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 1.02097165614658 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 0.938262449967509 | bayes_pls_golite062009 |
| transporter activity | 0.781252315942763 | bayes_pls_golite062009 |
| hydrolase activity | 0.539213162060111 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.523669943250984 | bayes_pls_golite062009 |
| actin binding | 0.4786890657602 | bayes_pls_golite062009 |
| nucleic acid binding | 0.476094076158571 | bayes_pls_golite062009 |
| structural molecule activity | 0.236653863910566 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.207376833349132 | bayes_pls_golite062009 |
| transcription regulator activity | 0.151103447043301 | bayes_pls_golite062009 |
| DNA binding | 0.143439914163001 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 0.125965304296204 | bayes_pls_golite062009 |
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Region A: Residues: [208-303] |
1 11 21 31 41 51
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1 APAHKIPAQT VVRRVRALYD LTTNEPDELS FRKGDVITVL EQVYRDWWKG ALRGNMGIFP 60
61 LNYVTPIVEP SKEEIEKEKN KEAIVFSQKT TIDQLH
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| Detection Method: | |
| Confidence: | 137.94696 |
| Match: | 1griA_ |
| Description: | Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2) |
Matching Structure (courtesy of the PDB):![]() |
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Region A: Residues: [304-452] |
1 11 21 31 41 51
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1 NSLNAASKTG NSNEVLQDPH IGDMYGSVTP LRPQVTRMLG KYAKEKEDML SLRQVLANAE 60
61 RSYNQLMDRA ANAHISPPVP GPALYAGMTH ANNTPVMPPQ RQSYQSNEYS PYPSNLPIQH 120
121 PTNSANNTPQ YGYDLGYSVV SQPPPGYEQ
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| Detection Method: | |
| Confidence: | 137.94696 |
| Match: | 1griA_ |
| Description: | Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2) |
Matching Structure (courtesy of the PDB):![]() |
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