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Protein Overview: gi|123997931, gi...

General Information:
Name(s) found: gi|123997931 [NCBI NR]
gi|123983224 [NCBI NR]
Description(s) found:
Found 2 descriptions.
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  • gi|123997931|gb|ABM86567.1| signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 [synthetic construct] [NCBI NR]
  • gi|123983224|gb|ABM83353.1| signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 [synthetic construct] [NCBI NR]
    • Organism: synthetic construct
    Length: 525 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLFTANPFE QDVEKATNEY NTTEDWSLIM DICDKVGSTP NGAKDCLKAI MKRVNHKVPH  60
   61 VALQALTLLG ACVANCGKIF HLEVCSRDFA TEVRAVIKNK AHPKVCEKLK SLMVEWSEEF 120
  121 QKDPQFSLIS ATIKSMKEEG ITFPPAGSQT VSAAAKNGTS SNKNKEDEDI AKAIELSLQE 180
  181 QKQQHTETKS LYPSSEIQLN NKVARKVRAL YDFEAVEDNE LTFKHGEIII VLDDSDANWW 240
  241 KGENHRGIGL FPSNFVTTNL NIETEAAAVD KLNVIDDDVE EIKKSEPEPV YIDEDKMDRA 300
  301 LQVLQSIDPT DSKPDSQDLL DLEDICQQMG PMIDEKLEEI DRKHSELSEL NVKVLEALEL 360
  361 YNKLVNEAPV YSVYSKLHPP AHYPPASSGV PMQTYPVQSH GGNYMGQSIH QVTVAQSYSL 420
  421 GPDQIGPLRS LPPNVNSSVT AQPAQTSYLS TGQDTVSNPT YMNQNSNLQS ATGTTAYTQQ 480
  481 MGMSVDMSSY QNTTSNLPQL AGFPVTVPAH PVAQQHTNYH QQPLL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..75] PSI-BLAST 40.69897 The solution structure of the VHS domain of human Signal transducing adaptor molecule 2
    2 View Details [76..161] FFAS03 3.67 The solution structure of the VHS domain of human Signal transducing adaptor molecule 2
    3 View Details [162..262] PSI-BLAST 12.09691 Solution structure of the SH3 domain of the Signal transducing adaptor molecule 2
    4 View Details [263..370] PSI-BLAST 10.522879 NMR ENSEMBLE OF BLK SH2 DOMAIN, 20 STRUCTURES
    5 View Details [371..465] FFAS03 1.06 Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP
    6 View Details [466..525] MSA 3.161995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  3.12724619324809 bayes_pls_golite062009
  • protein binding
    		•  2.14586566310919 bayes_pls_golite062009
  • molecular adaptor activity
    		•  1.33740973673697 bayes_pls_golite062009
  • SH3/SH2 adaptor activity
    		•  1.2323381312171 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.02097165614658 bayes_pls_golite062009
  • signal transducer activity
    		•  0.999269271132931 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.999269271132931 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.938262449967509 bayes_pls_golite062009
  • protein binding, bridging
    		•  0.83823250804321 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.540818657754841 bayes_pls_golite062009
  • hydrolase activity
    		•  0.539213162060111 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.476094076158571 bayes_pls_golite062009
  • DNA binding
    		•  0.281643350069021 bayes_pls_golite062009
  • phosphoprotein binding
    		•  0.16798254471727 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.125965304296204 bayes_pls_golite062009
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle