| Protein: | CWC22 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 577 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CWC22.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..577] | [1..577] |
|
|
0.0 | [1..490] | [399..912] |
|
|
0.0 | [1..492] | [171..687] |
|
|
0.0 | [1..495] | [103..618] |
|
|
0.0 | [1..494] | [342..855] |
|
|
0.0 | [1..480] | [173..677] |
|
Region A: Residues: [1-226] |
1 11 21 31 41 51
| | | | | |
1 MSTATIQDED IKFQRENWEM IRSHVSPIIS NLTMDNLQES HRDLFQVNIL IGRNIICKNV 60
61 VDFTLNKQNG RLIPALSALI ALLNSDIPDI GETLAKELML MFVQQFNRKD YVSCGNILQC 120
121 LSILFLYDVI HEIVILQILL LLLEKNSLRL VIAVMKICGW KLALVSKKTH DMIWEKLRYI 180
181 LQTQELSSTL RESLETLFEI RQKDYKSGSQ GLFILDPTSY TVHTHS
|
| Detection Method: |  |
| Confidence: | 45.0 |
| Match: | 1hu3A_ |
| Description: | Eukaryotic initiation factor eIF4G |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| RNA binding | 4.20683443264388 | bayes_pls_golite062009 |
| mRNA binding | 2.49094746544717 | bayes_pls_golite062009 |
| binding | 2.47395644967726 | bayes_pls_golite062009 |
| nucleic acid binding | 1.64539435934931 | bayes_pls_golite062009 |
| structural molecule activity | 1.39201458088376 | bayes_pls_golite062009 |
| transcription regulator activity | 1.06250847754412 | bayes_pls_golite062009 |
| protein binding | 1.04044934052933 | bayes_pls_golite062009 |
| DNA binding | 0.946847037737779 | bayes_pls_golite062009 |
| RNA cap binding | 0.66277586901495 | bayes_pls_golite062009 |
| transcription factor activity | 0.362911773502049 | bayes_pls_golite062009 |
|
Region A: Residues: [227-300] |
1 11 21 31 41 51
| | | | | |
1 YIVSDEDEAN KELGNFEKCE NFNELTMAFD TLRQKLLINN TSDTNEGSNS QLQIYDMTST 60
61 NDVEFKKKIY LVLK
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.648 | a.4.1 | Homeodomain-like |
| View | Download | 0.550 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.472 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.550 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.545 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.455 | f.28.1 | Nonheme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| View | Download | 0.430 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.422 | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.413 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.385 | d.88.1 | SRF-like |
| View | Download | 0.372 | d.230.1 | N-terminal, heterodimerisation domain of RBP4 (RpoE) |
| View | Download | 0.364 | a.3.1 | Cytochrome c |
| View | Download | 0.337 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.325 | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.308 | a.4.1 | Homeodomain-like |
| View | Download | 0.302 | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.293 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.292 | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.283 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.282 | a.2.2 | Ribosomal protein L29 (L29p) |
| View | Download | 0.266 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.264 | d.225.1 | Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| View | Download | 0.263 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.254 | d.52.1 | Alpha-lytic protease prodomain |
| View | Download | 0.250 | a.4.1 | Homeodomain-like |
| View | Download | 0.249 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.235 | a.2.2 | Ribosomal protein L29 (L29p) |
| View | Download | 0.234 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.220 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.219 | a.74.1 | Cyclin-like |
| View | Download | 0.208 | a.181.1 | Antibiotic binding domain of TipA-like multidrug resistance regulators |
| Term | Confidence | Notes |
| RNA binding | 4.05046860305563 | bayes_pls_golite062009 |
| binding | 2.36800795249393 | bayes_pls_golite062009 |
| mRNA binding | 2.35042158577052 | bayes_pls_golite062009 |
| nucleic acid binding | 1.59410102249793 | bayes_pls_golite062009 |
| structural molecule activity | 1.3916221897201 | bayes_pls_golite062009 |
| transcription regulator activity | 1.08645493064764 | bayes_pls_golite062009 |
| DNA binding | 0.956143892328242 | bayes_pls_golite062009 |
| protein binding | 0.914877292844892 | bayes_pls_golite062009 |
| transcription factor activity | 0.371244009721798 | bayes_pls_golite062009 |
| RNA cap binding | 0.357520253345298 | bayes_pls_golite062009 |
|
Region A: Residues: [301-514] |
1 11 21 31 41 51
| | | | | |
1 SSLSGDEAAH KLLKLKIANN LKKSVVDIII KSSLQESTFS KFYSILSERM ITFHRSWQTA 60
61 YNETFEQNYT QDIEDYETDQ LRILGKFWGH LISYEFLPMD CLKIIKLTEE ESCPQGRIFI 120
121 KFLFQELVNE LGLDELQLRL NSSKLDGMFP LEGDAEHIRY SINFFTAIGL GLLTEDMRSR 180
181 LTIIQEVEDA EEEEKKLREE EELEKLRKKA RESQ
|
| Detection Method: | |
| Confidence: | 7.46 |
| Match: | 1h6kA |
| Description: | CBP80, 80KDa nuclear cap-binding protein |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [515-577] |
1 11 21 31 41 51
| | | | | |
1 PTQGPKIHES RLFLQKDTRE NSRSRSPFTV ETRKRARSRT PPRGSRNHRN RSRTPPARRQ 60
61 RHR
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
