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View Structure Prediction Details

Protein: PET54
Organism: Saccharomyces cerevisiae
Length: 293 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PET54.

Description E-value Query
Range
Subject
Range
PET54_SACBA - Protein PET54 OS=Saccharomyces bayanus GN=PET54 PE=3 SV=1
0.0 [1..293] [1..294]
PET54_YEAST - Protein PET54 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PET54 PE=1 SV=1
PET54 - Mitochondrial inner membrane protein that binds to the 5' UTR of the COX3 mRNA to activate its trans...
0.0 [1..293] [1..293]

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Predicted Domain #1
Region A:
Residues: [1-293]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKASSKAIKL VLDHLKSTGR VLGSVESGNS ATISEKTASV NKQQQLQEKK PSVLQYRSYN  60
   61 PYLVKEDFLS ILPENLYKKR GQFTNELDFQ LMKVRDPKYF QFKDQYYLFF NDYNSLTEYI 120
  121 KLTKHSRINK IRVKMTPLAQ PLPTLLTKLQ RYSKNLYNAF RSSEQYFEGL NEKVDVSGEF 180
  181 TTNQLRSILD SVEEIENKSV LVWNIPTKLR SHDILNYFWF YNIRSSFKIY WDDEMKRNLR 240
  241 FISFENSHDA YRFKRNYHGL LAKELLTLSE KGDAADYSLE MDDSKILIEH LSE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [136-293]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPLAQPLPTL LTKLQRYSKN LYNAFRSSEQ YFEGLNEKVD VSGEFTTNQL RSILDSVEEI  60
   61 ENKSVLVWNI PTKLRSHDIL NYFWFYNIRS SFKIYWDDEM KRNLRFISFE NSHDAYRFKR 120
  121 NYHGLLAKEL LTLSEKGDAA DYSLEMDDSK ILIEHLSE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.19
Match: 2cqdA
Description: Solution Structure of the RNA recognition motif in RNA-binding region containing protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 3.6649737847299 bayes_pls_golite062009
RNA binding 3.54132281875185 bayes_pls_golite062009
mRNA binding 3.12096544084441 bayes_pls_golite062009
binding 3.05100551329453 bayes_pls_golite062009
2.65416081536729 bayes_pls_golite062009
transcription regulator activity 1.20182415212933 bayes_pls_golite062009
DNA binding 1.06738888024145 bayes_pls_golite062009
protein binding 1.05805521997665 bayes_pls_golite062009
structural molecule activity 0.767649718525223 bayes_pls_golite062009
poly-pyrimidine tract binding 0.761573507268535 bayes_pls_golite062009
single-stranded RNA binding 0.470675891495223 bayes_pls_golite062009
transcription factor activity 0.273768131383019 bayes_pls_golite062009
translation regulator activity 0.246220338604608 bayes_pls_golite062009
mRNA 3'-UTR binding 0.23733335659183 bayes_pls_golite062009
transcription factor binding 0.0848709019823142 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.0127733116412899 bayes_pls_golite062009
snRNA binding 0.00892689194659768 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle